G1 checkpoint is compromised in mouse ESCs due to functional uncoupling of p53-p21Waf1 signaling

Genome-wide profiling reveals stimulus-specific functions of p53 during differentiation and DNA damage of human embryonic stem cells

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Distinct Regulatory Mechanisms and Functions for p53-Activated and p53-Repressed DNA Damage Response Genes in Embryonic Stem Cells

(2012) Mangmang Li et al.   MOLECULAR CELL

MicroRNAs Regulate p21Waf1/Cip1 Protein Expression and the DNA Damage Response in Human Embryonic Stem Cells

(2012) Dasa Dolezalova et al.   STEM CELLS

Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation

(2012) Hao-Ming Chang et al.   Nature Communications

p53 Regulates Cell Cycle and MicroRNAs to Promote Differentiation of Human Embryonic Stem Cells

(2012) Abhinav K. Jain et al.   PLOS BIOLOGY

Activation of DNA damage response signaling in mouse embryonic stem cells

(2011) Ilya A. Chuykin et al.   CELL CYCLE

Two-phase dynamics of p53 in the DNA damage response

(2011) X.-P. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of p53 in embryonic stem cells

(2010) Valeriya Solozobova et al.   EXPERIMENTAL CELL RESEARCH

Nuclear accumulation and activation of p53 in embryonic stem cells after DNA damage

(2009) Valeriya Solozobova et al.   BMC CELL BIOLOGY

Survival responses of human embryonic stem cells to DNA damage

(2009) Tera M. Filion et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

(2009) Rosa M. Marión et al.   NATURE

Suppression of induced pluripotent stem cell generation by the p53–p21 pathway

(2009) Hyenjong Hong et al.   NATURE

Ionizing Radiation Induces Ataxia Telangiectasia Mutated-Dependent Checkpoint Signaling and G2But Not G1Cell Cycle Arrest in Pluripotent Human Embryonic Stem Cells

(2009) Olga Momčilović et al.   STEM CELLS

Small-Molecule Inhibitors of the MDM2-p53 Protein-Protein Interaction to Reactivate p53 Function: A Novel Approach for Cancer Therapy

(2008) Sanjeev Shangary et al.   Annual Review of Pharmacology and Toxicology

Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells

(2008) T Maimets et al.   ONCOGENE

p53 is required for etoposide-induced apoptosis of human embryonic stem cells

(2007) C. Grandela et al.   Stem Cell Research

Downregulation of Multiple Stress Defense Mechanisms During Differentiation of Human Embryonic Stem Cells

(2007) Gabriele Saretzki et al.   STEM CELLS