Article
Plant Sciences
Marie Kratka, Jakub Smerda, Katerina Lojdova, Petr Bures, Frantisek Zedek
Summary: The centromere drive model explains an evolutionary process caused by centromeric repeats expansion, resulting in preferential segregation of an expanded centromere. The histone protein CenH3 plays a key role in adaptive evolution to counter the detrimental effects of centromere drive. Holocentric chromosomes may prevent centromere drive through their unique kinetochore structure.
FRONTIERS IN PLANT SCIENCE
(2021)
Review
Genetics & Heredity
Hyung Jun Kim, Chenshu Liu, Abby F. Dernburg
Summary: This article summarizes the connections established between chromosomes and cytoplasmic motors via a nuclear envelope bridge during the early meiotic prophase, known as a LINC complex, and the promotion of chromosome and nuclear motions. While the molecular architecture of these connections has been illuminated in diverse organisms, important questions remain regarding their contributions to meiotic processes.
Article
Plant Sciences
Chiara Di Dio, Heidi Serra, Pierre Sourdille, James D. Higgins
Summary: During meiosis, ASYNAPSIS 1 (ASY1) promotes inter-homolog recombination, synapsis, and crossover formation. Decreased chiasmata and delayed meiotic prophase I progression were observed in asy1 hypomorphic mutants, while asy1 null mutants showed arrested development. On the other hand, the ectopic recombination between non-homologous chromosomes increased in these mutants. Therefore, asy1 mutants can be used to enhance recombination between wheat wild relatives and elite varieties for accelerating the introgression of important agronomic traits.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Ecology
Maria Ayelen Toscani, Maria Ines Pigozzi, Alba G. Papeschi, Maria Jose Bressa
Summary: Heteropteran insects exhibit diverse meiotic processes, making them suitable models to study chromosome behavior during cell division. Histone modifications serve as markers for distinguishing non-chiasmatic sex chromosomes from chiasmatic autosomal chromosomes. These findings provide insights into the mechanisms of chromosome behavior during meiosis in Heteroptera.
FRONTIERS IN ECOLOGY AND EVOLUTION
(2022)
Article
Plant Sciences
Aretuza Sousa, Veit Schubert, Susanne S. Renner
Summary: The study identified different types of sex chromosomes in liverworts, investigated their recombination environments using molecular cytogenetics and super-resolution microscopy, and found that the heteromorphic sex chromosomes in Frullania dilatata are distinct from autosomes and each other. The similarity between the U chromosomes suggests they may have originated from a non-disjunction event.
Article
Cell Biology
Eliana Ayarza, Gabriel Cavada, Tamara Arevalo, Alam Molina, Soledad Berrios
Summary: Robertsonian translocation is the most common chromosomal rearrangement in mammals, contributing to speciation in natural populations. In Mus musculus domesticus, Rb translocations lead to reduced chromosome numbers, with the metacentric Rb chromosome preferentially segregating in meiosis. However, our study found no evidence for preferential inheritance or random distribution of Rb chromosomes in M. domesticus.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Cell Biology
Laia Marin-Gual, Laura Gonzalez-Rodelas, Maria M. Garcias, Lukas Kratochvil, Nicole Valenzuela, Arthur Georges, Paul D. Waters, Aurora Ruiz-Herrera
Summary: This study compares the regulation of meiotic prophase I in reptiles by examining four species. The results show that meiosis progression is highly conserved in reptiles, with telomeres clustering forming the bouquet, promoting homologous pairing and synapsis. Low levels of meiotic double strand breaks were also detected in all taxa, providing new insights into reptile meiosis.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Ana Gil-Fernandez, Sergey Matveevsky, Marta Martin-Ruiz, Marta Ribagorda, Maria Teresa Parra, Alberto Viera, Julio S. Rufas, Oxana Kolomiets, Irina Bakloushinskaya, Jesus Page
Summary: Sex determination in mammals is typically based on XX in females and XY in males. However, Ellobius tancrei deviates from this norm, with both males and females having a pair of XX chromosomes that exhibit differential behavior in meiosis. While the male meiosis shows limited synapsis between the X chromosomes, leaving the central region completely unsynapsed, female meiosis experiences delayed synapsis in the central region. Recombination in the sex chromosomes is restricted in both sexes, with male meiosis showing differentiation of one of the sex chromosomes into a neo-Y and female meiosis lacking recombination in the central X chromosome region. These findings provide insights into the origin and evolution of sex chromosomes.
Review
Genetics & Heredity
Paul A. Saunders, Frederic Veyrunes
Summary: Therian mammals possess some of the oldest and most conserved sex-determining systems known, with deviations from the standard XX/XY constitution often leading to sterility or poor fertility. Some rodents, however, have unusual sex-determining systems, such as fertile XY females or species that have lost their Y chromosome, providing unique natural models for studying sex determination evolution in mammals and vertebrates.
Review
Cell Biology
Lexy von Diezmann, Ofer Rog
Summary: Crossover interference is a crucial process in sexual reproduction, but the molecular mechanisms behind it are still debated. Recent research has shed light on how signaling proteins regulate the formation of crossovers, providing new insights into this complex process. These findings contribute to a better understanding of how crossover interference is implemented in meiotic chromosomes.
JOURNAL OF CELL SCIENCE
(2021)
Review
Cell Biology
Mireia Sole, Alvaro Pascual, Ester Anton, Joan Blanco, Zaida Sarrate
Summary: Meiosis involves important events such as homologous chromosomal pairing, synapsis, recombination, and segregation, which contribute to reducing ploidy level and increasing genetic diversity. In most sexually reproducing eukaryotes, homologous chromosome pairing relies on mechanisms associated with DNA double-strand break repair and other pre-break formation processes. This article discusses various strategies used by model organisms for DSB-independent pairing, including chromosome clustering, nuclear and chromosome movements, specific proteins, non-coding RNA, and DNA sequences involvement.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2023)
Review
Ecology
Laura Ross, Andrew J. Mongue, Christina N. Hodson, Tanja Schwander
Summary: Reproduction is a key feature that distinguishes living organisms from inorganic matter, and the strategies for successful reproduction vary greatly among different organisms. In animals, the most common form of reproduction involves separate male and female sexes. However, fully symmetric reproduction, where both parents contribute equally to the offspring's genome, is the extreme end of a continuum towards complete asymmetry. This review explores the diversity of animal reproductive systems and suggests potential evolutionary routes towards increased levels of asymmetry.
ANNUAL REVIEW OF ECOLOGY EVOLUTION AND SYSTEMATICS
(2022)
Article
Genetics & Heredity
Ana Gil-Fernandez, Marta Ribagorda, Marta Martin-Ruiz, Pablo Lopez-Jimenez, Tamara Laguna, Rocio Gomez, Maria Teresa Parra, Alberto Viera, Frederic Veyrunes, Jesus Page
Summary: X and Y chromosomes in mammals differ in size and gene content due to an evolutionary process, with the Y chromosome undergoing differentiation and degeneration. The pseudoautosomal region (PAR) allows partial synapsis and reciprocal recombination of the sex chromosomes during meiosis, ensuring their segregation. The African pygmy mouse Mus mattheyi has completely differentiated sex chromosomes, with delayed pairing and unique protein dynamics, suggesting potential impact on sex chromosome divergence and transmission.
Article
Agronomy
Bowei Cai, Tai Wang, Fang Yue, Arrashid Harun, Bin Zhu, Wei Qian, Xianhong Ge, Zaiyun Li
Summary: Different digenomic autoallohexaploids with different copies of subgenomes were synthesized and their cytological behavior was analyzed. These autoallohexaploids showed variations in pollen fertility and seed-sets, and produced both euploid and aneuploid progenies. Aberrant pairings and segregations were observed in the subgenomes, and the regularity of meiosis was negatively associated with genome affinities.
THEORETICAL AND APPLIED GENETICS
(2022)
Article
Mathematics
Edward Hanson
Summary: This paper introduces a specific type of linear transformation pairs called Leonard pairs in a vector space and discusses the parameters used to describe these pairs. Two different characterizations of Leonard pairs are provided in the paper.
LINEAR & MULTILINEAR ALGEBRA
(2021)
Editorial Material
Multidisciplinary Sciences
Juliette Mathieu, Jean-Rene Huynh
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2017)
Article
Developmental Biology
Marie Clemot, Anahi Molla-Herman, Juliette Mathieu, Jean-Rene Huynh, Nathalie Dostatni
Article
Genetics & Heredity
Talia Hatkevich, Vincent Boudreau, Thomas Rubin, Paul S. Maddox, Jean-Rene Huynh, Jeff Sekelsky
Review
Cell Biology
Thomas Rubin, Nicolas Macaisne, Jean-Rene Huynh
Article
Biochemistry & Molecular Biology
Soline Chanet, Jean-Rene Huynh
Article
Genetics & Heredity
Anahi Molla-Herman, Margarita T. Angelova, Maud Ginestet, Clement Carre, Christophe Antoniewski, Jean-Rene Huynh
FRONTIERS IN GENETICS
(2020)
Article
Multidisciplinary Sciences
Juliette Mathieu, Pascale Michel-Hissier, Virginie Boucherit, Jean-Rene Huynh
Summary: The deubiquitinase USP8 plays a crucial role in regulating cell division in Drosophila, as it can transform incomplete divisions into complete divisions and vice versa. This process is mediated through the deubiquitination of ESCRT-III proteins CHMP2B and Shrub/CHMP4. Our findings highlight the importance of ubiquitination in controlling different types of cell division.
Article
Multidisciplinary Sciences
Adel Al Jord, Gaelle Letort, Soline Chanet, Feng-Ching Tsai, Christophe Antoniewski, Adrien Eichmuller, Christelle Da Silva, Jean-Rene Huynh, Nir S. Gov, Raphael Voituriez, Marie-Emilie Terret, Marie-Helene Verlhac
Summary: Cells can regulate the function of nuclear condensates through the use of cytoplasmic forces generated by cytoskeletal motors. This finding has implications for understanding and studying diseases associated with nuclear condensates.
NATURE COMMUNICATIONS
(2022)
Article
Multidisciplinary Sciences
Thomas Rubin, Nicolas Macaisne, Ana Maria Valles, Clara Guilleman, Isabelle Gaugue, Laurine Dal Toe, Jean-Rene Huynh
Summary: In Drosophila males, although meiosis differs significantly from females, similar molecular mechanisms are used to ensure proper pairing of centromeres.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Multidisciplinary Sciences
Catriona Munro, Hugo Cadis, Sophie Pagnotta, Evelyn Houliston, Jean-Rene Huynh
Summary: During meiosis, DNA recombination mediated by Spo11 enzyme triggers double-strand breaks (DSBs), which lead to the shuffling of genetic information between maternal and paternal chromosomes. In a study on the jellyfish Clytia hemisphaerica, they found that knocking down the Spo11 gene resulted in the failure of germ cells to assemble synaptonemal complexes and chiasmata, leading to the presence of unassociated homologous chromosome pairs and aneuploid but fertilizable eggs. This study provides significant evolutionary perspectives on meiosis regulation, as Clytia belongs to the sister clade of classical animal model species.
Review
Cell Biology
Ana Maria Valles, Jean-Rene Huynh
METHODS IN CELL BIOLOGY, VOL 158
(2020)
Article
Genetics & Heredity
Maelle Devilliers, Damien Garrido, Mickael Poidevin, Thomas Rubin, Arnaud Le Rouzic, Jacques Montagne
Summary: The study demonstrates the use of fruit flies as a powerful model to study the link between growth and metabolism, showing that TORC1 and Ilp signaling can independently regulate overgrowth, and that cell-autonomous metabolic defects may trigger local compensatory pathways.
