Apoptotic effects of high-dose rapamycin occur in S-phase of the cell cycle

Molecular damage in cancer: an argument for mTOR-driven aging

(2016) Mikhail V. Blagosklonny   Aging-US

eIF4E-mediated translational control of cancer incidence

(2015) Peter B. Bitterman et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Rapamycin-induced G1 cell cycle arrest employs both TGF-β and Rb pathways

(2015) Amrita Chatterjee et al.   CANCER LETTERS

Abstract A113: Chronic stress promotes lymph node metastasis through beta-adrenergic regulation of lymphangiogenesis

(2015) Caroline P. Le et al.   MOLECULAR CANCER RESEARCH

Tumor promoter-induced cellular senescence: cell cycle arrest followed by geroconversion

(2015) Olga V. Leontieva et al.   Oncotarget

Synchronization of the cell cycle using Lovastatin

(2014) Sonia JavanMoghadam-Kamrani et al.   CELL CYCLE

Phosphatidylinositol 3-Kinase (PI3K) and Phosphatidylinositol 3-Kinase-Related Kinase (PIKK) Inhibitors: Importance of the Morpholine Ring

(2014) Martin Andrs et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mutant Ras Elevates Dependence on Serum Lipids and Creates a Synthetic Lethality for Rapamycin

(2014) D. Salloum et al.   MOLECULAR CANCER THERAPEUTICS

Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus

(2014) Pengda Liu et al.   NATURE

Blocking anaplerotic entry of glutamine into the TCA cycle sensitizes K-Ras mutant cancer cells to cytotoxic drugs

(2014) M Saqcena et al.   ONCOGENE

Inhibition of S6 kinase suppresses the apoptotic effect of eIF4E ablation by inducing TGF-β-dependent G1 cell cycle arrest

(2013) Paige Yellen et al.   CANCER LETTERS

mTOR kinase inhibitors as potential cancer therapeutic drugs

(2013) Shi-Yong Sun   CANCER LETTERS

Glutamine and cancer: cell biology, physiology, and clinical opportunities

(2013) Christopher T. Hensley et al.   JOURNAL OF CLINICAL INVESTIGATION

The Translational Landscape of the Mammalian Cell Cycle

(2013) Craig R. Stumpf et al.   MOLECULAR CELL

Amino Acids and mTOR Mediate Distinct Metabolic Checkpoints in Mammalian G1 Cell Cycle

(2013) Mahesh Saqcena et al.   PLoS One

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

mTOR-Dependent Cell Survival Mechanisms

(2012) C.-M. Hung et al.   Cold Spring Harbor Perspectives in Biology

High-dose rapamycin induces apoptosis in human cancer cells by dissociating mTOR complex 1 and suppressing phosphorylation of 4E-BP1

(2011) Paige Yellen et al.   CELL CYCLE

Phosphatidic acid signaling to mTOR: Signals for the survival of human cancer cells

(2009) David A. Foster   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer

(2009) R J DeBerardinis et al.   ONCOGENE

eIF4E, the mRNA cap-binding protein: from basic discovery to translational researchThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB — Systems and Chemical Biology, and has undergone the Journal's usual peer review process.

(2008) Nahum Sonenberg   Biochemistry and Cell Biology

Regulation of mTORC1 and mTORC2 Complex Assembly by Phosphatidic Acid: Competition with Rapamycin

(2008) A. Toschi et al.   MOLECULAR AND CELLULAR BIOLOGY