Activin A inhibits BMP-signaling by binding ACVR2A and ACVR2B

Sotatercept in patients with osteolytic lesions of multiple myeloma

(2014) Kudrat M. Abdulkadyrov et al.   BRITISH JOURNAL OF HAEMATOLOGY

The role of bone morphogenetic proteins in myeloma cell survival

(2014) Toril Holien et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Transforming growth factor-β superfamily ligand trap ACE-536 corrects anemia by promoting late-stage erythropoiesis

(2014) Rajasekhar N V S Suragani et al.   NATURE MEDICINE

Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin

(2014) O E Olsen et al.   Blood Cancer Journal

Activins bind and signal via bone morphogenetic protein receptor type II (BMPR2) in immortalized gonadotrope-like cells

(2013) Carlis A. Rejon et al.   CELLULAR SIGNALLING

Bone marrow monocyte-/macrophage-derived activin A mediates the osteoclastogenic effect of IL-3 in multiple myeloma

(2013) R Silbermann et al.   LEUKEMIA

Activin, neutrophils, and inflammation: just coincidence?

(2013) Paschalis Sideras et al.   Seminars in Immunopathology

Circulating activin-A is elevated in patients with advanced multiple myeloma and correlates with extensive bone involvement and inferior survival; no alterations post-lenalidomide and dexamethasone therapy

(2012) E. Terpos et al.   ANNALS OF ONCOLOGY

The yin and yang of Activin A

(2011) S. Sozzani et al.   BLOOD

Bone morphogenetic proteins induce apoptosis in multiple myeloma cells by Smad-dependent repression of MYC

(2011) T Holien et al.   LEUKEMIA

New insights into the mechanisms of activin action and inhibition

(2011) Kelly L. Walton et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease

(2010) S. Vallet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BMP-2/4 and BMP-6/7 Differentially Utilize Cell Surface Receptors to Induce Osteoblastic Differentiation of Human Bone Marrow-derived Mesenchymal Stem Cells

(2008) Karen Lavery et al.   JOURNAL OF BIOLOGICAL CHEMISTRY