Transient cerebellar alterations during development prior to obvious motor phenotype in a mouse model of spinocerebellar ataxia type 6

Early hyperactivity and precocious maturation of corticostriatal circuits in Shank3B−/− mice

(2016) Rui T Peixoto et al.   NATURE NEUROSCIENCE

Developmental change in the contribution of voltage-gated Ca2+ channels to the pacemaking of deep cerebellar nuclei neurons

(2016) K. Alviña et al.   NEUROSCIENCE

4-aminopyridine reverses ataxia and cerebellar firing deficiency in a mouse model of spinocerebellar ataxia type 6

(2016) Sriram Jayabal et al.   Scientific Reports

In vivo analysis of Purkinje cell firing properties during postnatal mouse development

(2015) Marife Arancillo et al.   JOURNAL OF NEUROPHYSIOLOGY

Spinocerebellar Ataxia Type 6 Protein Aggregates Cause Deficits in Motor Learning and Cerebellar Plasticity

(2015) M. D. Mark et al.   JOURNAL OF NEUROSCIENCE

Neuronal Atrophy Early in Degenerative Ataxia Is a Compensatory Mechanism to Regulate Membrane Excitability

(2015) J. M. Dell'Orco et al.   JOURNAL OF NEUROSCIENCE

Neuronal morphometry directly from bitmap images

(2014) Tiago A Ferreira et al.   NATURE METHODS

Cell Types, Network Homeostasis, and Pathological Compensation from a Biologically Plausible Ion Channel Expression Model

(2014) Timothy O’Leary et al.   NEURON

A behavioural study of neuroglobin-overexpressing mice under normoxic and hypoxic conditions

(2013) Wendy Van Leuven et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Second Cistron in CACNA1A Gene Encodes a Transcription Factor Mediating Cerebellar Development and SCA6

(2013) Xiaofei Du et al.   CELL

Synapse elimination in the developing cerebellum

(2013) Kouichi Hashimoto et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Loss of the small heat shock protein αA-crystallin does not lead to detectable defects in early zebrafish lens development

(2013) Mason Posner et al.   EXPERIMENTAL EYE RESEARCH

Quantitative Localization of Cav2.1 (P/Q-Type) Voltage-Dependent Calcium Channels in Purkinje Cells: Somatodendritic Gradient and Distinct Somatic Coclustering with Calcium-Activated Potassium Channels

(2013) D. W. Indriati et al.   JOURNAL OF NEUROSCIENCE

Purkinje Cell Ataxin-1 Modulates Climbing Fiber Synaptic Input in Developing and Adult Mouse Cerebellum

(2013) B. A. Ebner et al.   JOURNAL OF NEUROSCIENCE

The Knockout of Secretin in Cerebellar Purkinje Cells Impairs Mouse Motor Coordination and Motor Learning

(2013) Li Zhang et al.   NEUROPSYCHOPHARMACOLOGY

Clinical characteristics of patients with spinocerebellar ataxias 1, 2, 3 and 6 in the US; a prospective observational study

(2013) Tetsuo Ashizawa et al.   Orphanet Journal of Rare Diseases

Selective Positive Modulator of Calcium-Activated Potassium Channels Exerts Beneficial Effects in a Mouse Model of Spinocerebellar Ataxia Type 2

(2012) Adebimpe W. Kasumu et al.   CHEMISTRY & BIOLOGY

Disruption of Purkinje cell function prior to huntingtin accumulation and cell loss in an animal model of Huntington Disease

(2012) S.E. Dougherty et al.   EXPERIMENTAL NEUROLOGY

Changes in Purkinje cell firing and gene expression precede behavioral pathology in a mouse model of SCA2

(2012) S. T. Hansen et al.   HUMAN MOLECULAR GENETICS

GABAergic Inhibition Regulates Developmental Synapse Elimination in the Cerebellum

(2012) Hisako Nakayama et al.   NEURON

Development of Purkinje cell degeneration in a knockin mouse model reveals lysosomal involvement in the pathogenesis of SCA6

(2012) T. Unno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of the cerebellum: from gene expression patterns to circuit maps

(2012) Joshua J. White et al.   Wiley Interdisciplinary Reviews-Developmental Biology

The metamorphosis of the developing cerebellar microcircuit

(2011) Ingrid van Welie et al.   CURRENT OPINION IN NEUROBIOLOGY

Aminopyridines Correct Early Dysfunction and Delay Neurodegeneration in a Mouse Model of Spinocerebellar Ataxia Type 1

(2011) R. Hourez et al.   JOURNAL OF NEUROSCIENCE

Mutant PKC  in Spinocerebellar Ataxia Type 14 Disrupts Synapse Elimination and Long-Term Depression in Purkinje Cells In Vivo

(2011) A. N. Shuvaev et al.   JOURNAL OF NEUROSCIENCE

Early Changes in Cerebellar Physiology Accompany Motor Dysfunction in the Polyglutamine Disease Spinocerebellar Ataxia Type 3

(2011) V. G. Shakkottai et al.   JOURNAL OF NEUROSCIENCE

Lobule-specific membrane excitability of cerebellar Purkinje cells

(2011) Chang-Hee Kim et al.   JOURNAL OF PHYSIOLOGY-LONDON

RhoE Deficiency Produces Postnatal Lethality, Profound Motor Deficits and Neurodevelopmental Delay in Mice

(2011) Enric Mocholí et al.   PLoS One

Postsynaptic P/Q-type Ca2+ channel in Purkinje cell mediates synaptic competition and elimination in developing cerebellum

(2011) K. Hashimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Therapeutic Mode of Action of 4-Aminopyridine in Cerebellar Ataxia

(2010) K. Alvina et al.   JOURNAL OF NEUROSCIENCE

Abnormalities in Metabolic Network Activity Precede the Onset of Motor Symptoms in Parkinson's Disease

(2010) C. C. Tang et al.   JOURNAL OF NEUROSCIENCE

Changes of motor abilities during ontogenetic development in Lurcher mutant mice

(2010) V. Markvartová et al.   NEUROSCIENCE

Motor coordination impairment in aged heterozygous rolling Nagoya, Cav2.1 mutant mice

(2009) Eiki Takahashi et al.   BRAIN RESEARCH

Traveling waves in developing cerebellar cortex mediated by asymmetrical Purkinje cell connectivity

(2009) Alanna J Watt et al.   NATURE NEUROSCIENCE

Activity-dependent plasticity of developing climbing fiber–Purkinje cell synapses

(2009) L.W.J. Bosman et al.   NEUROSCIENCE

Spinocerebellar ataxia type 6 knockin mice develop a progressive neuronal dysfunction with age-dependent accumulation of mutant CaV2.1 channels

(2008) K. Watase et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA