Renal extracellular vesicles: from physiology to clinical application

Vasopressin Regulates Extracellular Vesicle Uptake by Kidney Collecting Duct Cells

(2016) W. Oosthuyzen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Deubiquitylation of Protein Cargo Is Not an Essential Step in Exosome Formation

(2016) Alyssa R. Huebner et al.   MOLECULAR & CELLULAR PROTEOMICS

Isolation of urinary extracellular vesicles from Tamm- Horsfall protein–depleted urine and their application in the development of a lectin-exosome-binding assay

(2016) Maja Kosanović et al.   BIOTECHNIQUES

Cells release subpopulations of exosomes with distinct molecular and biological properties

(2016) Eduard Willms et al.   Scientific Reports

AKI Recovery Induced by Mesenchymal Stromal Cell-Derived Extracellular Vesicles Carrying MicroRNAs

(2015) F. Collino et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Exosome isolation: a microfluidic road-map

(2015) A. Liga et al.   LAB ON A CHIP

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

Urinary tract infections: epidemiology, mechanisms of infection and treatment options

(2015) Ana L. Flores-Mireles et al.   NATURE REVIEWS MICROBIOLOGY

Ectosomes and exosomes: shedding the confusion between extracellular vesicles

(2015) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

Microfluidic isolation of cancer-cell-derived microvesicles from hetergeneous extracellular shed vesicle populations

(2014) Steven M. Santana et al.   BIOMEDICAL MICRODEVICES

Double-stranded DNA in exosomes: a novel biomarker in cancer detection

(2014) Basant Kumar Thakur et al.   CELL RESEARCH

Biogenesis and secretion of exosomes

(2014) Joanna Kowal et al.   CURRENT OPINION IN CELL BIOLOGY

Exosomal ATF3 RNA Attenuates Pro-Inflammatory Gene MCP-1 Transcription in Renal Ischemia-Reperfusion

(2014) Hsi-Hsien Chen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Identification of Biomarkers for PKD1 Using Urinary Exosomes

(2014) M. C. Hogan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Human Urinary Exosomes as Innate Immune Effectors

(2014) T. F. Hiemstra et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Discovery of an integrative network of microRNAs and transcriptomics changes for acute kidney injury

(2014) Chan Gyu Lee et al.   KIDNEY INTERNATIONAL

Microfluidic device (ExoChip) for on-chip isolation, quantification and characterization of circulating exosomes

(2014) Shailender Singh Kanwar et al.   LAB ON A CHIP

Rationale of Mesenchymal Stem Cell Therapy in Kidney Injury

(2014) Susanne V. Fleig et al.   NEPHRON CLINICAL PRACTICE

Rapid Isolation of Extracellular Vesicles from Cell Culture and Biological Fluids Using a Synthetic Peptide with Specific Affinity for Heat Shock Proteins

(2014) Anirban Ghosh et al.   PLoS One

Urinary extracellular microvesicles: Isolation methods and prospects for urinary proteome

(2014) Danqi Wang et al.   PROTEOMICS

Sorting it out: Regulation of exosome loading

(2014) Carolina Villarroya-Beltri et al.   SEMINARS IN CANCER BIOLOGY

Human liver stem cells and derived extracellular vesicles improve recovery in a murine model of acute kidney injury

(2014) Maria Sanchez et al.   Stem Cell Research & Therapy

Endogenous RNAs Modulate MicroRNA Sorting to Exosomes and Transfer to Acceptor Cells

(2014) Mario Leonardo Squadrito et al.   Cell Reports

Post-Translational Modifications of Exosomal Proteins

(2014) Olga Moreno-Gonzalo et al.   Frontiers in Immunology

Use and Isolation of Urinary Exosomes as Biomarkers for Diabetic Nephropathy

(2014) Luca Musante et al.   Frontiers in Endocrinology

Bioinspired Exosome-Mimetic Nanovesicles for Targeted Delivery of Chemotherapeutics to Malignant Tumors

(2013) Su Chul Jang et al.   ACS Nano

A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy

(2013) Yanhua Tian et al.   BIOMATERIALS

Antigen-specific, antibody-coated, exosome-like nanovesicles deliver suppressor T-cell microRNA-150 to effector T cells to inhibit contact sensitivity

(2013) Krzysztof Bryniarski et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies

(2013) Johnny C. Akers et al.   JOURNAL OF NEURO-ONCOLOGY

Quantification of human urinary exosomes by nanoparticle tracking analysis

(2013) Wilna Oosthuyzen et al.   JOURNAL OF PHYSIOLOGY-LONDON

A New Look at Tubulointerstitial Communication with Exosomes

(2013) H. Okada   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Subfractionation, characterization, and in-depth proteomic analysis of glomerular membrane vesicles in human urine

(2013) Marie C. Hogan et al.   KIDNEY INTERNATIONAL

Characterization and deep sequencing analysis of exosomal and non-exosomal miRNA in human urine

(2013) Lesley Cheng et al.   KIDNEY INTERNATIONAL

Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma

(2013) Hina Kalra et al.   PROTEOMICS

Urinary Exosomes as a Source of Kidney Dysfunction Biomarker in Renal Transplantation

(2013) S. Alvarez et al.   TRANSPLANTATION PROCEEDINGS

Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

(2013) Carolina Villarroya-Beltri et al.   Nature Communications

Exosomes released by human umbilical cord mesenchymal stem cells protect against cisplatin-induced renal oxidative stress and apoptosis in vivo and in vitro

(2013) Ying Zhou et al.   Stem Cell Research & Therapy

The Complete Exosome Workflow Solution: From Isolation to Characterization of RNA Cargo

(2013) Jeoffrey Schageman et al.   Biomed Research International

Kidney Protection and Regeneration Following Acute Injury: Progress Through Stem Cell Therapy

(2012) Florian E. Tögel et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Rab27a Supports Exosome-Dependent and -Independent Mechanisms That Modify the Tumor Microenvironment and Can Promote Tumor Progression

(2012) A. Bobrie et al.   CANCER RESEARCH

Calcium-phosphate microprecipitates mimic microparticles when examined with flow cytometry

(2012) Michael C. Larson et al.   CYTOMETRY PART A

The Long and Short of MicroRNAs in the Kidney

(2012) J. Ho et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

TGF- 1-Containing Exosomes from Injured Epithelial Cells Activate Fibroblasts to Initiate Tissue Regenerative Responses and Fibrosis

(2012) F. T. Borges et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Microparticles and microRNAs of endothelial progenitor cells ameliorate acute kidney injury

(2012) Markus Bitzer et al.   KIDNEY INTERNATIONAL

Microvesicles derived from endothelial progenitor cells protect the kidney from ischemia–reperfusion injury by microRNA-dependent reprogramming of resident renal cells

(2012) Vincenzo Cantaluppi et al.   KIDNEY INTERNATIONAL

Comparison of protein, microRNA, and mRNA yields using different methods of urinary exosome isolation for the discovery of kidney disease biomarkers

(2012) M. Lucrecia Alvarez et al.   KIDNEY INTERNATIONAL

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

Therapeutic potential of mesenchymal stem cell-derived microvesicles

(2012) L. Biancone et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Microvesicles Derived from Mesenchymal Stem Cells Enhance Survival in a Lethal Model of Acute Kidney Injury

(2012) Stefania Bruno et al.   PLoS One

Biochemical and Physical Characterisation of Urinary Nanovesicles following CHAPS Treatment

(2012) Luca Musante et al.   PLoS One

Urinary exosomes: A reservoir for biomarker discovery and potential mediators of intrarenal signalling

(2012) James W. Dear et al.   PROTEOMICS

Application of systems biology principles to protein biomarker discovery: Urinary exosomal proteome in renal transplantation

(2012) Trairak Pisitkun et al.   Proteomics Clinical Applications

Exosomal transmission of functional aquaporin 2 in kidney cortical collecting duct cells

(2011) Jonathan M. Street et al.   JOURNAL OF PHYSIOLOGY-LONDON

More on: calibration for the measurement of microparticles: needs, interests, and limitations of calibrated polystyrene beads for flow cytometry-based quantification of biological microparticles

(2011) F. MULLIER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Exosomes and the kidney: prospects for diagnosis and therapy of renal diseases

(2011) Bas W.M. van Balkom et al.   KIDNEY INTERNATIONAL

Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain

(2011) Xiaoying Zhuang et al.   MOLECULAR THERAPY

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

Mesenchymal stem cells in kidney inflammation and repair

(2011) ANDREA F. WISE et al.   NEPHROLOGY

Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury

(2011) S. Gatti et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Urinary Exosomes

(2011) Irena Dimov et al.   TheScientificWorldJOURNAL

Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences

(2011) Leonora Balaj et al.   Nature Communications

Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

(2011) María Mittelbrunn et al.   Nature Communications

Biliary exosomes influence cholangiocyte regulatory mechanisms and proliferation through interaction with primary cilia

(2010) Anatoliy I. Masyuk et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes

(2010) H. Sheldon et al.   BLOOD

Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A–C

(2010) Chieh Hsu et al.   JOURNAL OF CELL BIOLOGY

Microvesicles: mediators of extracellular communication during cancer progression

(2010) V. Muralidharan-Chari et al.   JOURNAL OF CELL SCIENCE

Therapeutic Applications of Mesenchymal Stem Cells to Repair Kidney Injury

(2010) Hiroshi Asanuma et al.   JOURNAL OF UROLOGY

Exosomes/microvesicles as a mechanism of cell-to-cell communication

(2010) Giovanni Camussi et al.   KIDNEY INTERNATIONAL

Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome

(2010) Ilse M. Rood et al.   KIDNEY INTERNATIONAL

Tamm-Horsfall protein and urinary exosome isolation

(2010) Patricia Fernández-Llama et al.   KIDNEY INTERNATIONAL

Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease

(2010) Kevin C. Miranda et al.   KIDNEY INTERNATIONAL

A Novel Nanoparticle Drug Delivery System: The Anti-inflammatory Activity of Curcumin Is Enhanced When Encapsulated in Exosomes

(2010) Dongmei Sun et al.   MOLECULAR THERAPY

ARF6-Regulated Shedding of Tumor Cell-Derived Plasma Membrane Microvesicles

(2009) Vandhana Muralidharan-Chari et al.   CURRENT BIOLOGY

Astrocytes and Glioblastoma cells release exosomes carrying mtDNA

(2009) Michele Guescini et al.   JOURNAL OF NEURAL TRANSMISSION

Characterization of PKD Protein-Positive Exosome-Like Vesicles

(2009) M. C. Hogan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Rab27a and Rab27b control different steps of the exosome secretion pathway

(2009) Matias Ostrowski et al.   NATURE CELL BIOLOGY

Multipotent mesenchymal stromal cell therapy in renal disease and kidney transplantation

(2009) M. E.J. Reinders et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Shedding microvesicles: artefacts no more

(2009) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

Large-Scale Proteomics and Phosphoproteomics of Urinary Exosomes

(2008) P. A. Gonzales et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY