Using physiologically based models for clinical translation: predictive modelling, data interpretation or something in-between?

The relative role of patient physiology and device optimisation in cardiac resynchronisation therapy: A computational modelling study

(2016) Andrew Crozier et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Estimation of passive and active properties in the human heart using 3D tagged MRI

(2015) Liya Asner et al.   Biomechanics and Modeling in Mechanobiology

Beneficial Effect on Cardiac Resynchronization From Left Ventricular Endocardial Pacing Is Mediated by Early Access to High Conduction Velocity Tissue

(2015) Eoin R. Hyde et al.   Circulation-Arrhythmia and Electrophysiology

Differentiating Electromechanical From Non–Electrical Substrates of Mechanical Discoordination to Identify Responders to Cardiac Resynchronization TherapyCLINICAL PERSPECTIVE

(2015) Joost Lumens et al.   Circulation-Cardiovascular Imaging

Epigenetic Profiling Identifies Novel Genes for Ascending Aortic Aneurysm Formation with Bicuspid Aortic Valves

(2015) Asad A Shah   HEART SURGERY FORUM

Improving the Stability of Cardiac Mechanical Simulations

(2015) Sander Land et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

3D harmonic phase tracking with anatomical regularization

(2015) Yitian Zhou et al.   MEDICAL IMAGE ANALYSIS

Towards Personalized Cardiology: Multi-Scale Modeling of the Failing Heart

(2015) Elham Kayvanpour et al.   PLoS One

Verification of cardiac mechanics software: benchmark problems and solutions for testing active and passive material behaviour

(2015) Sander Land et al.   PROCEEDINGS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Uncertainty quantification of fast sodium current steady-state inactivation for multi-scale models of cardiac electrophysiology

(2015) Pras Pathmanathan et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Diagnostic accuracy and discrimination of ischemia by fractional flow reserve CT using a clinical use rule: Results from the Determination of Fractional Flow Reserve by Anatomic Computed Tomographic Angiography study

(2015) Angus G. Thompson et al.   Journal of Cardiovascular Computed Tomography

Virtual Electrophysiological Study of Atrial Fibrillation in Fibrotic Remodeling

(2015) Kathleen S. McDowell et al.   PLoS One

Images as drivers of progress in cardiac computational modelling

(2014) Pablo Lamata et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Cardiac Resynchronization Therapy in Patients With Heart Failure and a QRS Complex

(2013) Bernard Thibault et al.   CIRCULATION

Feasibility of image-based simulation to estimate ablation target in human ventricular arrhythmia

(2013) Hiroshi Ashikaga et al.   HEART RHYTHM

Comparative Electromechanical and Hemodynamic Effects of Left Ventricular and Biventricular Pacing in Dyssynchronous Heart Failure

(2013) Joost Lumens et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Computational Fluid Dynamics Applied to Cardiac Computed Tomography for Noninvasive Quantification of Fractional Flow Reserve

(2013) Charles A. Taylor et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A vision and strategy for the virtual physiological human: 2012 update

(2013) P. Hunter et al.   Interface Focus

Ensuring reliability of safety-critical clinical applications of computational cardiac models

(2013) Pras Pathmanathan et al.   Frontiers in Physiology

Preterm Heart in Adult Life

(2012) Adam J. Lewandowski et al.   CIRCULATION

Confirmation of Novel Noninvasive High-Density Electrocardiographic Mapping With Electrophysiology Study

(2012) Ivan Cakulev et al.   Circulation-Arrhythmia and Electrophysiology

The Role of Physiologically Based Pharmacokinetic Modeling in Regulatory Review

(2012) S-M Huang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Best Practice in the Use of Physiologically Based Pharmacokinetic Modeling and Simulation to Address Clinical Pharmacology Regulatory Questions

(2012) P Zhao et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Quality Metrics for High Order Meshes: Analysis of the Mechanical Simulation of the Heart Beat

(2012) Pablo Lamata et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Mortality from ischaemic heart disease by country, region, and age: Statistics from World Health Organisation and United Nations

(2012) Judith A. Finegold et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Diagnostic Accuracy of Fractional Flow Reserve From Anatomic CT Angiography

(2012) James K. Min et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A finite-element approach to the direct computation of relative cardiovascular pressure from time-resolved MR velocity data

(2012) Sebastian B.S. Krittian et al.   MEDICAL IMAGE ANALYSIS

The estimation of patient-specific cardiac diastolic functions from clinical measurements

(2012) Jiahe Xi et al.   MEDICAL IMAGE ANALYSIS

Analyses of the Redistribution of Work following Cardiac Resynchronisation Therapy in a Patient Specific Model

(2012) Steven Alexander Niederer et al.   PLoS One

The Cardiac Atlas Project—an imaging database for computational modeling and statistical atlases of the heart

(2011) Carissa G. Fonseca et al.   BIOINFORMATICS

Reproducible computational biology experiments with SED-ML - The Simulation Experiment Description Markup Language

(2011) Dagmar Waltemath et al.   BMC Systems Biology

Cost-effectiveness of transcatheter aortic valve replacement in patients ineligible for conventional aortic valve replacement

(2011) Maureen Watt et al.   HEART

Incompressible Deformation Estimation Algorithm (IDEA) From Tagged MR Images

(2011) Xiaofeng Liu et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Patient-specific electromechanical models of the heart for the prediction of pacing acute effects in CRT: A preliminary clinical validation

(2011) M. Sermesant et al.   MEDICAL IMAGE ANALYSIS

Biophysical Modeling to Simulate the Response to Multisite Left Ventricular Stimulation Using a Quadripolar Pacing Lead

(2011) STEVEN A. NIEDERER et al.   PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY

Verification of cardiac tissue electrophysiology simulators using an N-version benchmark

(2011) S. A. Niederer et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Efficient probabilistic model personalization integrating uncertainty on data and parameters: Application to Eikonal-Diffusion models in cardiac electrophysiology

(2011) Ender Konukoglu et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Coupled personalization of cardiac electrophysiology models for prediction of ischaemic ventricular tachycardia

(2011) J. Relan et al.   Interface Focus

euHeart: personalized and integrated cardiac care using patient-specific cardiovascular modelling

(2011) N. Smith et al.   Interface Focus

Simulating Human Cardiac Electrophysiology on Clinical Time-Scales

(2011) Steven Niederer et al.   Frontiers in Physiology

Length-dependent tension in the failing heart and the efficacy of cardiac resynchronization therapy

(2010) Steven A. Niederer et al.   CARDIOVASCULAR RESEARCH

Applications of Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation During Regulatory Review

(2010) P Zhao et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Wave-Direction and Conduction-Velocity Analysis From Intracardiac Electrograms–A Single-Shot Technique

(2010) Frank M Weber et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Evaluation of a multi-atlas based method for segmentation of cardiac CTA data: a large-scale, multicenter, and multivendor study

(2010) H. A. Kirişli et al.   MEDICAL PHYSICS

A vision and strategy for the virtual physiological human in 2010 and beyond

(2010) P. Hunter et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Three-Wall Segment (TriSeg) Model Describing Mechanics and Hemodynamics of Ventricular Interaction

(2009) Joost Lumens et al.   ANNALS OF BIOMEDICAL ENGINEERING

Mathematical Modeling of Electrocardiograms: A Numerical Study

(2009) Muriel Boulakia et al.   ANNALS OF BIOMEDICAL ENGINEERING

A meta-analysis of cardiac electrophysiology computational models

(2009) S. A. Niederer et al.   EXPERIMENTAL PHYSIOLOGY

A subject-specific technique for respiratory motion correction in image-guided cardiac catheterisation procedures

(2009) A.P. King et al.   MEDICAL IMAGE ANALYSIS

FieldML: concepts and implementation

(2009) G. R. Christie et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Coupling multi-physics models to cardiac mechanics

(2009) D.A. Nordsletten et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

The CellML Model Repository

(2008) C. M. Lloyd et al.   BIOINFORMATICS

Automatic Model-Based Segmentation of the Heart in CT Images

(2008) O. Ecabert et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Myocardial deformation recovery from cine MRI using a nearly incompressible biventricular model

(2008) A BISTOQUET et al.   MEDICAL IMAGE ANALYSIS