Article
Mathematics, Applied
Lucia M. Wagner, Sara M. Clifton
Summary: Since the introduction of electronic cigarettes to the U.S. market in 2007, vaping prevalence has increased significantly in adult and adolescent populations. Concerns have been raised by the U.S. government and health professionals about the attraction of e-cigarettes to young non-smokers. A dynamical systems model was developed to analyze the competition between traditional and electronic cigarettes, predicting changes in smoking prevalence and determining the conditions under which e-cigarettes may benefit or harm society's public health.
Article
Plant Sciences
Jasmina Kurepa, Timothy E. Shull, Anne Fisher, Colin Fisher, Huihua Ji, Jan A. Smalle
Summary: The study found that different varieties of tobacco accumulate TSNAs at different levels during curing, with NCBH 129LC containing higher levels of TSNAs. Further experiments showed that NCBH 129LC had significantly higher hydrogen peroxide levels than KT 204LC, as well as more oxidatively damaged and glutathionylated proteins.
JOURNAL OF PLANT PHYSIOLOGY
(2021)
Editorial Material
Critical Care Medicine
Adam Edward Lang, Aleksandra Yakhkind
Summary: In December 2019, a US Army training battalion in Virginia decided to ban tobacco and nicotine products after surveying trainee soldiers. The implementation process involved careful planning and data collection to address nicotine dependence and improve the health of soldiers. The intervention model offers comprehensive resources and therapy for long-term quitting.
Article
Psychology, Clinical
Jasmina Mallet, Ophelia Godin, Yecodji Dansou, Nicolas Mazer, Claire Scognamiglio, Fabrice Berna, Laurent Boyer, Delphine Capdevielle, Isabelle Chereau, Thierry D'Amato, Julien Dubreucq, Guillaume Fond, Sylvain Leigner, Pierre-Michel Llorca, David Misdrahi, Christine Passerieux, Romain Rey, Baptiste Pignon, Mathieu Urbach, Benoit Schorr, Franck Schuerhoff, Le Strat Yann, Caroline Dubertret
Summary: This study is one of the largest to date and provides strong evidence that chronic smoking is associated with cognitive impairment in schizophrenia patients. This goes against the self-medication hypothesis and suggests that ex-smokers may represent a specific subgroup.
PSYCHOLOGICAL MEDICINE
(2023)
Review
Surgery
Sukriti Mohan, Jamil S. Samaan, Kamran Samakar
Summary: The association between smoking and postoperative weight loss outcomes in bariatric surgery patients is not significant based on current evidence. However, more robust studies are needed to confirm this relationship due to the variability in study designs and analyses.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Review
Biochemistry & Molecular Biology
Yupeng Li, Stephen S. Hecht
Summary: NNK and NNN are tobacco-specific nitrosamines that have been identified as carcinogens for humans. Significant progress has been made in understanding their metabolism, DNA adduct formation, carcinogenicity, and mutagenicity over the past 20 years. This review aims to provide an update on the carcinogenicity and mechanisms of metabolism and DNA interactions of NNK and NNN.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Medicine, Research & Experimental
Pamela M. Lai, Mako Araga, Ana Hamilton, Marianna Armogida
Summary: Cigarette smoking is a significant public health issue. Nicotine replacement therapy (NRT) is an effective treatment to aid in quitting smoking. The prototype mini lozenge was found to be bioequivalent to a commercially available mini lozenge.
ADVANCES IN THERAPY
(2021)
Review
Substance Abuse
Neal L. Benowitz, Evangelia Liakoni
Summary: This narrative review discusses the impact of cigarette smoking and other tobacco/nicotine products on cardiovascular disease, highlighting the importance of rapid risk reduction after quitting smoking. In addition to cigarette smoking, the review also examines the effects of other combustible tobacco products, smokeless tobacco, electronic nicotine delivery systems, and second-hand smoke on cardiovascular health.
Article
Plant Sciences
Lucien Bovet, Prisca Campanoni, Jian Lu, Aurore Hilfiker, Samuel Kleinhans, Helene Laparra, Joanne Schwaar, Ramsey S. Lewis, Yuki Matsuba, Hong Ma, Ralph E. Dewey, Simon Goepfert
Summary: This study found that suppressing expression or knocking-out the CLCNt2 gene can directly impact the reduction of leaf nitrate and TSNAs, without altering biomass. This provides a possibility for breeding new commercial tobacco varieties with reduced TSNA levels.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Psychology, Clinical
John A. Cunningham, Vladyslav Kushnir, Peter Selby, Laurie Zawertailo, Rachel F. Tyndale, Scott T. Leatherdale, Alexandra Godinho, Christina Schell
Summary: This secondary analysis of a randomized trial of mailed nicotine patches found that purchasing additional NRT was not associated with long-term success in tobacco cessation. Current smokers continue to show interest in NRT for quitting smoking.
ADDICTIVE BEHAVIORS
(2021)
Article
Health Care Sciences & Services
Jaimee L. Heffner, Scott Coggeshall, Chelle L. Wheat, Paul Krebs, Laura C. Feemster, Deborah E. Klein, Linda Nici, Hannah Johnson, Steven B. Zeliadt
Summary: This study evaluated smoking cessation treatment receipt and 1-year post-screening cessation outcomes in the Veterans Health Administration. Findings showed that only a small percentage of veterans who received tobacco treatment were able to quit smoking, and treatment and cessation were influenced by various factors.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2022)
Article
Environmental Sciences
Lianjie Hou, Qin He, Yu Wang, Xixi Feng, Yali Mi, Shuang Li, Jie Feng Deng, Guojun Zhao
Summary: This study found that nicotine can induce macrophage pyroptosis by increasing the expression of LINC01272, which competitively binds with miR-515, reducing the inhibitory effect of miR-515 on its target gene KLF6. This finding is important for understanding the mechanism of nicotine-induced atherosclerosis.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Review
Public, Environmental & Occupational Health
Alireza Jafari, Abdolhalim Rajabi, Mahdi Gholian-Aval, Nooshin Peyman, Mehrsadat Mahdizadeh, Hadi Tehrani
Summary: This systematic review and meta-analysis revealed a high prevalence of cigarette smoking among women worldwide, with a pooled prevalence of 28% for ever smoking and 17% for current smoking. Educational programs are crucial for reducing smoking prevalence among women.
ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE
(2021)
Review
Psychiatry
Anna Grunze, Sergey Mosolov, Heinz Grunze, Christoph Born
Summary: This narrative review examines the epidemiology, consequences, and treatment options of tobacco use disorder (TUD) and nicotine dependence (ND) in individuals with bipolar disorder (BD). The study found that smoking rates are 2-3 times higher in individuals with BD compared to community samples. Smoking has a detrimental impact on both mental and physical health as well as mortality in individuals with BD. Treatment options include pharmacological interventions and psychosocial interventions.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Substance Abuse
Lauren Arancini, Ron Borland, Michael Le Grande, Mohammadreza Mohebbi, Seetal Dodd, Olivia M. Dean, Michael Berk, Ann McNeill, Geoffrey T. Fong, K. Michael Cummings
Summary: The study found that older smokers were more likely to smoke daily and less likely to attempt and succeed in quitting smoking. Younger smokers were more likely to achieve at least 30 days of abstinence, but the age effect disappeared when controlling for heaviness of smoking. Significant interactions were found between age and intention when predicting quit attempts, and age and heaviness of smoking when predicting quit success.
Article
Neurosciences
Suzanne M. de la Monte, Ming Tong, Irio Schiano, John Didsbury
JOURNAL OF ALZHEIMERS DISEASE
(2017)
Article
Public, Environmental & Occupational Health
Chukwuemeka N. Okafor, Natalie E. Kelso, Vaughn Bryant, Larry E. Burrell, Maria Jose Miguez, Assawin Gongvatana, Karen T. Tashima, Suzanne de la Monte, Robert L. Cook, Ronald A. Cohen
PSYCHOLOGY HEALTH & MEDICINE
(2017)
Article
Pathology
John E. Donahue, Evgeny Yakirevich, Shan Zhong, Diana O. Treaba, Nelli S. Lakis, Siraj M. Ali, Suzanne M. de la Monte, Shamlal Mangray
PEDIATRIC AND DEVELOPMENTAL PATHOLOGY
(2018)
Article
Substance Abuse
Suzanne M. de la Monte, Jared Kay, Emine B. Yalcin, Jillian J. Kril, Donna Sheedy, Greg T. Sutherland
Meeting Abstract
Pharmacology & Pharmacy
Rohitash Jamwal, Benjamin J. Barlock, Sravani Adusumalli, Ken Ogasawara, Suzanne M. De La Monte, Fatemeh Akhlaghi
DRUG METABOLISM AND PHARMACOKINETICS
(2018)
Review
Neurosciences
Suzanne M. de la Monte, Ming Tong, Jack R. Wands
JOURNAL OF ALZHEIMERS DISEASE
(2018)
Article
Pediatrics
David E. Mandelbaum, Amanda Arsenault, Barbara S. Stonestreet, Stefan Kostadinov, Suzanne M. De La Monte
JOURNAL OF PEDIATRICS
(2018)
Article
Geriatrics & Gerontology
Brian R. Ott, Richard N. Jones, Lori A. Daiello, Suzanne M. de la Monte, Edward G. Stopa, Conrad E. Johanson, Charles Denby, Paula Grammas
FRONTIERS IN AGING NEUROSCIENCE
(2018)
Article
Biochemistry & Molecular Biology
Suzanne M. de la Monte, Ming Tong, Andrew J. Hapel
Summary: Neuroinflammation may serve as a pathogenic mediator and biomarker of neurodegeneration in the transition between mild cognitive impairment (MCI) and early-stage Alzheimer's disease (AD). This study suggests that early management of MCI/AD neuroinflammation should involve both anti-inflammatory and pro-neuroprotective strategies.
Article
Nutrition & Dietetics
Emine B. Yalcin, Ming Tong, Camilla Homans, Suzanne M. de la Monte
Summary: Chronic heavy alcohol exposure can cause alcoholic liver disease, but it can be improved by using the serine palmitoyltransferase inhibitor myriocin, which may regulate the composition of hepatic phospholipids containing docosahexaenoic acid and arachidonic acid.
NUTRITION AND METABOLIC INSIGHTS
(2022)
Article
Pediatrics
Sonja Chen, Fouad Zakkat, Salwa Khedrt, Shamlal Mangrayt, Lauren Massingham, Suzanne M. de la Monte
JOURNAL OF PEDIATRIC NEUROLOGY
(2020)
Article
Medicine, Research & Experimental
Suzanne M. de la Monte, Gina M. Gallucci, Amy Lin, Ming Tong, Xiaodi Chen, Barbara S. Stonestreet
Meeting Abstract
Substance Abuse
C. C. Smith, M. B. O'Rourke, M. Padula, S. M. De La Monte, D. L. Sheedy, J. J. Kril, G. T. Sutherland
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
(2018)
Meeting Abstract
Clinical Neurology
Suzanne de la Monte, Ming Tong, Gina Gallucci, Emine Yalcin, Edward Stopa, Miles Miller, Jared Kay
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
(2018)
Article
Substance Abuse
Emine B. Yalcin, Tory McLean, Ming Tong, Suzanne M. de la Monte