Periodic mesoporous organosilica for chromatographic stationary phases: From synthesis strategies to applications

Periodic mesoporous organosilica (PMO) materials with organic functionalities in mesoporous frame-works have received a lot of attention in multiple fields. This particular review focuses on the improvement of chromatographic separation benefitting from the superiority of PMO stationary phases, including packed columns and monolithic columns. To understand the correlation between PMO chro-matographic stationary phase compositions and chromatographic performance, we summarize the functional bridges, synthesis methods, and modification methods. The research directions for further development of a more highly efficient PMO chromatographic column are outlooked.(c) 2022 Elsevier B.V. All rights reserved.

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This review article focuses on the application of periodic mesoporous organosilica (PMO) materials with organic functionalities in chromatographic separation, including packed columns and monolithic columns. The correlation between PMO chromatographic stationary phase compositions and chromatographic performance is discussed by summarizing the functional bridges, synthesis methods, and modification methods. The research directions for further development of a more highly efficient PMO chromatographic column are also outlined.