Conformational change of α-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson’s disease

Structures of α-synuclein filaments from human brains with Lewy pathology

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Hierarchical chemical determination of amyloid polymorphs in neurodegenerative disease

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Seeded assembly in vitro does not replicate the structures of α‐synuclein filaments from multiple system atrophy

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Challenges in the diagnosis of Parkinson's disease

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Novel tau filament fold in corticobasal degeneration

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Amyloid structure determination in RELION-3.1

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Structures of α-synuclein filaments from multiple system atrophy

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Parkinson’s disease-related phosphorylation at Tyr39 rearranges α-synuclein amyloid fibril structure revealed by cryo-EM

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Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules

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α-Synuclein strains target distinct brain regions and cell types

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Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy

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Cellular milieu imparts distinct pathological α-synuclein strains in α-synucleinopathies

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Cryo-EM structure of alpha-synuclein fibrils

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Amyloid fibril structure of α-synuclein determined by cryo-electron microscopy

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Structures of filaments from Pick’s disease reveal a novel tau protein fold

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Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel

(2018) Binsen Li et al.   Nature Communications

Tau filaments from multiple cases of sporadic and inherited Alzheimer’s disease adopt a common fold

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Helical reconstruction in RELION

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Cryo-EM structures of tau filaments from Alzheimer’s disease

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AlphaLISA detection of alpha-synuclein in the cerebrospinal fluid and its potential application in Parkinson’s disease diagnosis

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Development of a Biochemical Diagnosis of Parkinson Disease by Detection of α-Synuclein Misfolded Aggregates in Cerebrospinal Fluid

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Validation of the rapid eye movement sleep behavior disorder screening questionnaire in China

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CTFFIND4: Fast and accurate defocus estimation from electron micrographs

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MDS clinical diagnostic criteria for Parkinson's disease

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Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

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Prion-like spreading of pathological α-synuclein in brain

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Structural and functional characterization of two alpha-synuclein strains

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Neuropathology underlying clinical variability in patients with synucleinopathies

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Epidemiology and etiology of Parkinson’s disease: a review of the evidence

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Can Parkinson's disease pathology be propagated from one neuron to another?

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Features and development ofCoot

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Targeted Amino-Terminal Acetylation of Recombinant Proteins in E. coli

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Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

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