Review
Biochemistry & Molecular Biology
Sarah Monserrat Lomeli Martinez, Nadia Guadalupe Carrillo Contreras, Juan Ramon Gomez Sandoval, Jose Sergio Zepeda Nuno, Juan Carlos Gomez Mireles, Juan Jose Varela Hernandez, Ana Esther Mercado-Gonzalez, Ruben Alberto Bayardo Gonzalez, Adrian Fernando Gutierrez-Maldonado
Summary: This article reviews the epidemiology, etiopathogenesis, clinical manifestations, and management of pyogenic granuloma (PG). It emphasizes the importance of accurate diagnosis for effective treatment and provides details on personalized treatment approaches.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Dermatology
Katharina Strobel, Katja Maurus, Henning Hamm, Sabine Roth, Matthias Goebeler, Andreas Rosenwald, Marion Wobser
Summary: This study investigates the molecular profile of sporadic pyogenic granuloma and identifies novel oncogenic mutations in key genes of the mitogen-activated protein kinase pathway. The results provide evidence that activated mitogen-activated protein kinase signalling is a key driver in the pathogenesis of pyogenic granuloma.
ACTA DERMATO-VENEREOLOGICA
(2022)
Article
Dermatology
Jing Li, Changhua Wu, Dan Song, Liang Wang, Lei Guo
Summary: The study demonstrates that sclerotherapy with 1.0% polidocanol is an effective treatment for pediatric PG, with early treatment associated with a more favorable outcome. The procedure resulted in complete excision of PG with inconspicuous scars, well-tolerated, and no observed recurrence, allergic reactions, cutaneous necrosis, or pigmentary changes.
DERMATOLOGIC SURGERY
(2021)
Article
Pathology
Laura Nordio, Cristiano Stefanello, Stefania Gasparini
Summary: Oral fibroepithelial polyps (FEPs) are common benign lesions that develop slowly in sites of local irritation or trauma. This study analyzed FEPs in 21 dogs and found that they commonly occur under or lateral to the tongue. The lesions are characterized by a thick fibrovascular stalk and hyperplastic squamous epithelium with frequent inflammation and ulceration. Surgical excision of FEPs resulted in no recurrence. Chronic irritation may play a causative role in the pathogenesis of FEPs in dogs.
VETERINARY PATHOLOGY
(2023)
Review
Medicine, General & Internal
Yuheng Yang, Xiaoping Ye, Binjie Fu, Zhui Li, Yangyang Feng, Yu Zhao, Hong Liu
Summary: Preoperative diagnosis of IVPG is challenging, and a combination of multiple imaging examinations is necessary to exclude differential diagnoses. Surgical excision resulted in complication-free postoperative follow-up for the patient.
Article
Dentistry, Oral Surgery & Medicine
Nieves Roman-Quesada, Beatriz Gonzalez-Navarro, Keila Izquierdo-Gomez, Enric Jane-Salas, Antonio Mari-Roig, Albert Estrugo-Devesa, Jose Lopez-Lopez
Summary: The study aimed to evaluate the recurrence of peripheral giant cell granuloma and pyogenic granuloma associated with dental implants. Results showed that tissue excision is the main therapeutic approach, with a high recurrence rate (34.4%) which often requires explantation of the associated implant.
Review
Dermatology
Ying-Hua Song, Dan Chen, Shuang Deng, Wei-Na Cai, Liang Zhang
Summary: This case report presents a successful experience of using superficial radiation therapy to treat the recurrent neoplasm in a 27-year-old female patient.
DERMATOLOGIC THERAPY
(2023)
Review
Emergency Medicine
Christopher E. Gaw, James R. Treat, Eron Y. Friedlaender, Jeannine Del Pizzo
Summary: This article explores the management of actively bleeding pyogenic granulomas in acute care settings, offering various therapeutic strategies available to emergency physicians, such as direct pressure and topical vasoconstrictors.
JOURNAL OF EMERGENCY MEDICINE
(2022)
Article
Ophthalmology
Rey Nemoto, Yoshihiko Usui, Hiroyuki Komatsu, Kinya Tsubota, Risa Sugawara, Toshitaka Nagao, Hiroshi Goto
Summary: This study evaluated the immunophenotypic profiles of infiltrating cells in surgically excised tissues of chalazion and chalazion-associated pyogenic granuloma. The findings showed a similar immunophenotypic profile in both conditions, with predominant T cell infiltration and CD4 T cells dominating over CD8 cells.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2023)
Article
Dermatology
Abd El-Aziz Ibrahim El-Taweel, Abdul-Aziz Abdul-Salam Ahmed Al-Refaie, Khalid Hamdy Awad Salem, Rehab Mohammed Salem
Summary: The study found that the topical use of propranolol 1% and timolol 0.5% creams shows potential in treating pyogenic granulomas, especially in younger patients. While 40% of lesions did not change in size in the beta-blocker treated groups, they all reported a decreased bleeding tendency, and no recurrence was reported in patients with complete resolution after three months of follow-up.
JOURNAL OF COSMETIC DERMATOLOGY
(2021)
Article
Pathology
Adam L. Booth, Lysandra Voltaggio, Rebecca Waters, John Goldblum, Michael M. Feely, Diana Agostini-Vulaj, Maryam Pezhouh, Raul S. Gonzalez
Summary: This study describes the clinical and pathological features of lobular capillary hemangioma (LCH) in the gastrointestinal (GI) tract. LCHs in the GI tract often manifest as colorectal polyps, typically small in size and can be multifocal. Follow-up information showed no same-site recurrence in the patients.
AMERICAN JOURNAL OF CLINICAL PATHOLOGY
(2023)
Article
Surgery
Kodai Nagakari, Akikazu Yago, Yu Ohkura, Daisuke Tomita, Shusuke Haruta, Yutaka Takazawa, Masaki Ueno
Summary: This case report presents a rare case of intestinal intussusception and progressive anemia caused by pyogenic granuloma of the ileum, successfully treated with laparoscopic-assisted small bowel resection. Surgeons should consider the possibility of tumor in similar cases and complete surgical resection is crucial for management.
SURGICAL CASE REPORTS
(2021)
Article
Medicine, General & Internal
Eder Luna-Ceron, Ana K. Gomez-Gutierrez, Cinthia Gonzalez-Hernandez, Michelle Gatica-Torres
Summary: Benign vascular neoplasms are common clinical problems in primary care, with pyogenic granulomas being one of the most common benign vascular lesions in young adults. The development of pyogenic granulomas is associated with triggers such as retinoid treatment, biological agents, invasive cutaneous therapies, and trauma. Cases of pyogenic granulomas within vascular malformations like port wine stains are rare, with occurrences reported during pregnancy or after cryotherapy or pulsated laser therapy.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Dong Hyeon Kim, Hee Jung Lee, Jin Young Kim, Hye Ra Jung
Summary: Umbilical polyps and granulomas in children can be differentiated based on their ultrasonographic features, with polyps showing deep-seated nodules with cyst formation and granulomas showing superficial hypervascular solid nodules. These findings can aid in clinical diagnosis and management.
Review
Medicine, General & Internal
Mohammad S. Bin Dlaim, Ghadah A. Alhussein, Raneem S. Alqahtani, Leenah T. Almanea
Summary: Ocular pyogenic granuloma is a benign vascular tumor commonly found in children. Treatment options include steroids, timolol, surgery, cryotherapy, and electrocautery. In this case, a giant pyogenic granuloma in a 13-year-old girl regressed completely after timolol treatment, demonstrating it as a potential noninvasive alternative to surgery.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
