Allosteric autoregulation of DNA binding via a DNA-mimicking protein domain: a biophysical study of ZNF410–DNA interaction using small angle X-ray scattering

Development of a double shmiR lentivirus effectively targeting both BCL11A and ZNF410 for enhanced induction of fetal hemoglobin to treat β-hemoglobinopathies

(2022) Boya Liu et al.   MOLECULAR THERAPY

HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription

(2022) Peng Huang et al.   NATURE GENETICS

A Zinc Finger Transcription Factor Faithfully Dedicated to Only a Single Target Gene in Erythroid Cells

(2021) Juhyun Kim et al.   MOLECULAR CELL

Targeting ZNF410 as a potential β-hemoglobinopathy therapy

(2021) Laxminath Tumburu et al.   NATURE GENETICS

ZNF410 represses fetal globin by singular control of CHD4

(2021) Divya S. Vinjamur et al.   NATURE GENETICS

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

X‐ray scattering reveals disordered linkers and dynamic interfaces in complexes and mechanisms for DNA double‐strand break repair impacting cell and cancer biology

(2021) Michal Hammel et al.   PROTEIN SCIENCE

A Bacteriophage DNA Mimic Protein Employs a Non-specific Strategy to Inhibit the Bacterial RNA Polymerase

(2021) Zhihao Wang et al.   Frontiers in Microbiology

Structural insights into glucocorticoid receptor function

(2021) Filipp Frank et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Recent advances in small-angle scattering and its expanding impact in structural biology

(2021) Jill Trewhella   STRUCTURE

HRI-regulated transcription factor ATF4 activates BCL11A transcription to silence fetal hemoglobin expression

(2020) Peng Huang et al.   BLOOD

ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression

(2020) Xianjiang Lan et al.   MOLECULAR CELL

The complex relationship between TFEB transcription factor phosphorylation and subcellular localization

(2018) Rosa Puertollano et al.   EMBO JOURNAL

Structure–function analyses of the bacterial zinc metalloprotease effector protein GtgA uncover key residues required for deactivating NF-κB

(2018) Elliott Jennings et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New paradigm of functional regulation by DNA mimic proteins: Recent updates

(2018) Hao-Ching Wang et al.   IUBMB LIFE

SAXSMoW 2.0: Online calculator of the molecular weight of proteins in dilute solution from experimental SAXS data measured on a relative scale

(2018) Vassili Piiadov et al.   PROTEIN SCIENCE

Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA

(2017) Hideharu Hashimoto et al.   MOLECULAR CELL

Disabling Cas9 by an anti-CRISPR DNA mimic

(2017) Jiyung Shin et al.   Science Advances

The p53 Pathway: Origins, Inactivation in Cancer, and Emerging Therapeutic Approaches

(2016) Andreas C. Joerger et al.   Annual Review of Biochemistry

deepTools2: a next generation web server for deep-sequencing data analysis

(2016) Fidel Ramírez et al.   NUCLEIC ACIDS RESEARCH

FoXS, FoXSDock and MultiFoXS: Single-state and multi-state structural modeling of proteins and their complexes based on SAXS profiles

(2016) Dina Schneidman-Duhovny et al.   NUCLEIC ACIDS RESEARCH

Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin

(2016) T. Masuda et al.   SCIENCE

A practical guide to small angle X-ray scattering (SAXS) of flexible and intrinsically disordered proteins

(2015) Alexey G. Kikhney et al.   FEBS LETTERS

Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry

(2015) Weixing Zhao et al.   MOLECULAR CELL

The NuRD architecture

(2013) Hillary F. Allen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Accurate assessment of mass, models and resolution by small-angle scattering

(2013) Robert P. Rambo et al.   NATURE

Conformational changes in DNA-binding proteins: Relationships with precomplex features and contributions to specificity and stability

(2013) Munazah Andrabi et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

How Random are Intrinsically Disordered Proteins? A Small Angle Scattering Perspective

(2012) Veronique Receveur-Brechot et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

NF-κB regulation: lessons from structures

(2012) Gourisankar Ghosh et al.   IMMUNOLOGICAL REVIEWS

Identifying ChIP-seq enrichment using MACS

(2012) Jianxing Feng et al.   Nature Protocols

Characterizing flexible and intrinsically unstructured biological macromolecules by SAS using the Porod-Debye law

(2011) Robert P. Rambo et al.   BIOPOLYMERS

Structural studies of NF-κB signaling

(2010) Chao Zheng et al.   CELL RESEARCH

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Structure and flexibility within proteins as identified through small angle X-ray scattering

(2009) M. Pelikan et al.   GENERAL PHYSIOLOGY AND BIOPHYSICS

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY