Review
Chemistry, Analytical
H. K. Melvin Ng, G. K. Lim, C. P. Leo
Summary: Carbon dots (CDs) are nanomaterials with photoluminescence properties useful for detecting hazardous materials, synthesized from biowaste and chemicals through methods like hydrothermal and microwave-assisted synthesis. Additional dopants like nitrogen and sulfur can enhance their performance, and immobilization into a solid substrate allows for reuse. Interaction with heavy metals enables quantification of heavy metal concentrations in water samples.
MICROCHEMICAL JOURNAL
(2021)
Review
Chemistry, Multidisciplinary
Adam Truskewycz, Hong Yin, Nils Halberg, Daniel T. H. Lai, Andrew S. Ball, Vi Khanh Truong, Agata Marta Rybicka, Ivan Cole
Summary: This article discusses the therapeutic potential of carbon quantum dots (CQDs) in biomedical applications. CQDs have shown biocompatibility and have been used for drug solubility, targeting, and facilitating drug delivery. They can also be triggered by environmental conditions or external stimuli, and their fluorescence is valuable for diagnostic purposes. The article also examines the toxicity of CQDs and their compatibility with larger nanoparticle carriers. The future of CQDs in theragnostic applications looks promising due to their multifunctional attributes and biocompatibility.
Article
Biotechnology & Applied Microbiology
Seokhwan Chung, Miqin Zhang
Summary: The study presents a novel iron oxide and carbon dot based nanoparticle (CNPCP) with optical properties similar to traditional fluorescent probes and good biocompatibility. In vitro evaluation in cancer cell lines showed these nanoparticles to be non-toxic and effective for imaging. Additionally, conjugation of model therapeutic doxorubicin onto the NPs demonstrated their potential for delivering chemotherapeutics in a dose-dependent manner.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Chemistry, Applied
Da-jian Jv, Tian-hao Ji, Zhemi Xu, Ao Li, Zhong-yi Chen
Summary: A study found that the combination of lutein and carbon dots through solvent-ultrasonic treatment at room temperature can enhance the photostability and antioxidant capacity of lutein, thereby expanding its application in the food and biomedical fields.
Article
Chemistry, Multidisciplinary
Viviana Bressi, Alina M. Balu, Daniela Iannazzo, Claudia Espro
Summary: Carbon dots (CDs) are a new class of zero-dimensional nano-materials that have excellent properties such as photostability, biocompatibility, fluorescence, and ease of surface modification. The use of renewable biomass, especially waste biomass, for the synthesis of green CDs has gained significant attention as it provides a green solution to waste management goals and circular economy. This article highlights recent advances in the green synthesis and formation mechanism of CDs from biomass, with a focus on innovative one-pot hydrothermal and microwave processes.
CURRENT OPINION IN GREEN AND SUSTAINABLE CHEMISTRY
(2023)
Article
Biochemical Research Methods
Zhao Xu, Cong Zhang, Xu Yu, Heng Zheng, Li Xu
Summary: The microwave-assisted solid-phase synthesis method was employed to produce nitrogen-doping carbon dots (N-CDs) with high fluorescence quantum yield and stability, which were used for the detection of sunitinib. Combining proper sample pretreatment and N-CD probe, fluorescence detection of sunitinib was achieved.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Applied
Yan Liang, Dongyuan Hou, Zan Ni, Minjie Cao, Luyun Cai
Summary: In this study, naringenin loaded beta-cyclodextrin and carbon quantum dots composite nanoparticles were successfully synthesized and characterized. The results showed that the incorporation of carbon quantum dots improved the antioxidant activities of the nanoparticles and the encapsulation efficiency of naringenin. The formed composite nanoparticles displayed enhanced antioxidant properties compared to their individual constituents.
Article
Chemistry, Multidisciplinary
Xue Chen, Yu Wang, Chenxi Peng, Wenbo Hu, Zhongbin Wu, Weidong Xu, Suli Wu, Zhi Luo, Yung Doug Suh, Timur Sh. Atabaev, Xiyan Li, Xiaowang Liu, Wei Huang
Summary: This paper reports a novel method for synthesizing CD-doped SiO(2) MPs with tunable afterglow properties and size distributions. The pseudomorphic transformation of SiO(2) MPs enables CD doping, providing a hydrogen bond-enriched environment for triplet state stabilization, resulting in green afterglow while maintaining uniformity in size and morphology. Furthermore, the utility of CD-doped SiO(2) MPs in the fabrication of PC patterns is demonstrated, exhibiting multiple optical responses under different lighting conditions.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Physical
Jianting Li, Wenjuan Fu, Xiangying Zhang, Qijia Zhang, Dandan Ma, Yuting Wang, Wenhui Qian, Dong Zhu
Summary: In this study, ginger-derived carbon dots (GCDs) were prepared and showed excellent biocompatibility and anti-inflammatory effect. GCDs accelerated wound healing by inhibiting the expression of proinflammatory factors through blocking the TLR4-mediated NF kappa B pathway. The findings suggest the promising application of GCDs as imaging tools and functional wound dressings.
Article
Chemistry, Analytical
Qihui Wang, Xiaodan Qi, Hongying Chen, Jiagen Li, Min Yang, Jun Liu, Kang Sun, Zhonghui Li, Guowei Deng
Summary: CD-MOFs, which were successfully synthesized, exhibit excellent stability and fluorescence intensity in water. A sensitive fluorescent sensor based on CD-MOFs was constructed for the determination of chloramphenicol with high precision.
Article
Environmental Sciences
Chengzhi Xu, Xiao Xiao, Chaonan Cai, Qunpeng Cheng, Lian Zhu, Juntao Zhang, Benmei Wei, Haibo Wang
Summary: In this study, carbon dots (CDs) were prepared from waste fish scales, and the effects of hydrothermal and microwave methods on their fluorescence properties and structures were evaluated. The microwave method facilitated self-doping of nitrogen, but resulted in incomplete dehydration and condensation, forming nanosheet-like CDs with emission behavior independent of excitation. The CDs prepared using the conventional hydrothermal method showed higher quantum yields and excitation wavelength-dependent emission behavior due to the dehydration and condensation of organic matter at controlled high temperature and sealed environment.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Review
Chemistry, Multidisciplinary
Beatrice Bartolomei, Jacopo Dosso, Maurizio Prato
Summary: Carbon dots are currently a hot topic in nanomaterial research, but their preparation methods have faced challenges such as high temperatures, long reaction times, and toxic solvents. Innovative chemistry fields like mechanochemistry, flow chemistry, and laser synthesis could offer potential solutions to these issues. Additionally, machine learning could be utilized to expand the properties and applications of carbon dots.
TRENDS IN CHEMISTRY
(2021)
Article
Materials Science, Multidisciplinary
Wenkai Chen, Yangsheng Zhong, Gangrong Fu, Wenxuan Lai, Ziwen Pan, Yulian Yang, Fangyan Chen, Huichao Yan
Summary: This study presents a green and effective method for fabricating fluorescent silkworm silk with enhanced mechanical properties. Carbon dots synthesized from citric acid and urea were used as additives and incorporated into silkworm feed. The CD-modified silk showed improved mechanical properties and safety for the silkworms, making it a promising high-quality fluorescent silk production method.
Article
Environmental Sciences
Jasneet Kaur, Monika Bhattu, Mohit Rawat, Rajender S. Varma, Roberto Acevedo, Mohamed Shaban, Sameerah I. Al-Saeedi, Jagpreet Singh
Summary: This study presents a facile and cost-effective method for the preparation of carbon dots and carbon dot silver nanocomposites using peanut shells through hydrothermal treatment. The synthesized carbon dot silver nanocomposites showed excellent catalytic activity, sensing ability towards heavy metal ions, and antimicrobial potential. The integration of catalysis, sensing, and antimicrobial potentials in this study provides an effective remediation platform.
ENVIRONMENTAL RESEARCH
(2023)
Article
Materials Science, Ceramics
Lei Zhang, Bo Li, Yue Zhou, Yan Wu, Tao Le, Qi Sun
Summary: A fluorescent probe based on cow milk-derived carbon quantum dots (CMCQDs) was synthesized and exhibited blue fluorescence, small particle size, and excellent stability. It demonstrated high selectivity and sensitivity in detecting ferric ions (Fe3+) in tap water, with a LOD of 0.6 μmol/L in the range of 0.1-20 μmol/L (R-2 = 0.9911). The quenching effect of CMCQDs by Fe3+ is attributed to the unique chelation or coordination between Fe3+ and surface functional groups of CMCQDs.
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Physical
Katarzyna Skibinska, Konrad Wojtaszek, Lukas Krause, Anna Kula, Xuegeng Yang, Mateusz M. Marzec, Marek Wojnicki, Piotr Zabinski
Summary: Catalysts with tailored composition prepared by a simple electrochemical process exhibit distinct catalytic activity towards hydrogen and oxygen evolution reactions. In this study, Co-Ni cones were synthesized using a one-step method and their catalytic performance was strongly influenced by changes in surface composition caused by controlled oxidation. The spontaneously formed oxide layer decreased the catalytic performance compared to the fresh sample. Proper storage of synthesized catalysts is essential for maintaining desired catalytic applications.
APPLIED SURFACE SCIENCE
(2023)
Article
Metallurgy & Metallurgical Engineering
Karolina Kolczyk-Siedlecka, Robert P. Socha, Xuegeng Yang, Kerstin Eckert, Marek Wojnicki
Summary: This paper presents the potential use of carbon sorbents in recovering rhenium(VII) from highly diluted electrolytes. Activated carbon is found to be a suitable sorbent due to its high chemical resistance and osmotic-shock resistance. The sorption mechanism is complex and strongly influenced by temperature.
Article
Chemistry, Physical
Arpad Turcsanyi, Ditta Ungor, Marek Wojnicki, Edit Csapo
Summary: Fabrication protocol of BSA- and LYZ-stabilized Au/Ag NCs was optimized by adjusting the protein/metal ion ratios, metal concentration, pH, and incubation time. The incorporation of silver into the gold core significantly enhanced the fluorescence properties of the nanoclusters. The stability of the bimetallic NCs during interaction with biocolloids was much higher compared to monometallic derivatives, indicating their potential as fluorescent reporters in biomedical applications.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Physical
Konrad Wojtaszek, Filip Cebula, Bogdan Rutkowski, Magdalena Wytrwal, Edit Csapo, Marek Wojnicki
Summary: This study synthesized core-shell nanoparticles with a Ni core and a Ag-Ni nano alloy shell by reducing Ni and Ag ions with sodium borohydride in the presence of trisodium citrate as a stabilizer. XRD and XPS spectroscopic studies were conducted to determine the phase composition and oxidation states of the nanoparticles, respectively. The composition and shape of the particles were determined using HR-TEM EDS testing. The obtained nanoparticles had a size of 11 nm. Catalytic activity research was carried out using a methylene blue reduction system, and the catalytic activity of the colloids was measured using UV-Vis spectrophotometry. The Ag-Ni alloy exhibited approximately ten times higher catalytic activity than pure silver nanoparticles of a similar size.
Article
Biochemistry & Molecular Biology
Monika Marcinkowska, Barbara Mordyl, Agata Siwek, Monika Gluch-Lutwin, Tadeusz Karcz, Alicja Gawalska, Michal Sapa, Adam Bucki, Katarzyna Szafranska, Bartosz Pomierny, Karolina Pytka, Magdalena Kotanska, Kamil Mika, Marcin Kolaczkowski
Summary: In this study, a set of dually acting molecules were designed to modulate GABA-A and 5-HT6 receptor activity simultaneously, aiming to improve therapeutic outcomes in treatment-resistant depression. Lead molecule 16 showed desirable receptor profile and physicochemical properties, reducing proinflammatory cytokine secretion and oxidative stress markers. Animal studies demonstrated antidepressant-like activity of 16 through synergic interplay between 5-HT6 and GABA-A receptors. These findings suggest that hybrid molecule 16 is an interesting tool that interacts with pharmacologically relevant targets, matching the pathological dysfunction of depression associated with neuroinflammation.
ACS CHEMICAL NEUROSCIENCE
(2023)
Article
Engineering, Civil
Lukasz Rakoczy, Malgorzata Grudzien-Rakoczy, Bogdan Rutkowski, Rafal Cygan, Fabian Hanning, Grzegorz Cios, Stefan Habisch, Joel Andersson, Peter Mayr, Anna Zielinska-Lipiec
Summary: This study investigates the influence of microstructural constituents on liquation crack formation in the cast Ni-based superalloy, Rene 108. It is found that the base material has a complex microstructure, including gamma matrix, gamma' precipitates, MC and M23C6 carbides, and M5B3 borides. The constitutional liquation in the alloy leads to a significant reduction in strength and ductility, resulting in low weldability. In the heat-affected zone, mainly gamma' precipitates undergo constitutional liquation, forming a thin non-equilibrium liquid film along high-angle grain boundaries, which initiates and propagates cracks during cooling.
ARCHIVES OF CIVIL AND MECHANICAL ENGINEERING
(2023)
Article
Biochemistry & Molecular Biology
Kamil Mika, Malgorzata Szafarz, Marek Bednarski, Agata Siwek, Katarzyna Szczepanska, Katarzyna Kiec-Kononowicz, Magdalena Kotanska
Summary: This study evaluated the safety of histamine H-3/sigma-2 receptor ligands by assessing their effects on various parameters. The results showed that the ligands tested at a specific dose did not have negative effects on locomotor activity, motor coordination, cardiac function, blood pressure, and cellular enzymes. These findings suggest that the ligands are safe for further research.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Malgorzata Frankowska, Karolina Wydra, Agata Suder, Magdalena Zaniewska, Dawid Gawlinski, Joanna Miszkiel, Anna Furgala-Wojas, Kinga Salat, Malgorzata Filip, Christa E. Mueller, Katarzyna Kiec-Kononowicz, Magdalena Kotanska
Summary: This study discovered three novel selective ligands for GPR18, including one agonist and two antagonists. The activation of GPR18 has similar effects to the CB receptor system, impacting emotional behavior, food intake, and pain activity. Therefore, GPR18 represents a potential therapeutic target for mood, pain, and/or eating disorders.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Materials Science, Multidisciplinary
Konrad Wojtaszek, Tomasz Tokarski, Dawid Kutyla, Karolina Kolczyk-Siedlecka, Piotr Zabinski, Edit Csapo, Robert P. Socha, Marc Escriba-Gelonch, Volker Hessel, Marek Wojnicki
Summary: The paper presents research results on synthesizing silver nanoparticles in aqueous solutions and their extraction into the organic phase. The extraction process is most effective using n-hexane > cyclohexane > toluene > chloroform > ethyl acetate. The dielectric constant of the organic phase has a correlation with its ability to extract nanoparticles, with lower dielectric constant leading to higher extractability. The transfer of silver nanoparticles to the organic phase also affects their hydrodynamic radius and particle shape, highlighting the complexity of interfacial processes.
Article
Pharmacology & Pharmacy
Norbert Varga, Rita Belteki, Adam Juhasz, Edit Csapo
Summary: Using Tween20 and Pluronic F127 as stabilizers, the non-steroid anti-inflammatory drug ketoprofen (KP) is encapsulated in poly(lactide-co-glycolide) (PLGA) nanostructured particles, demonstrating the design of a biocompatible colloidal carrier with highly controllable drug release. The formation of a well-defined core-shell structure is observed using nanoprecipitation method. Stabilized polymer-based colloids with a hydrodynamic diameter of around 200-210 nm can be achieved by optimizing the KP concentration with the appropriate stabilizer. The release of the drug from the PLGA carrier particles is greatly influenced by the molecular weight and structure of the stabilizer.
Article
Chemistry, Multidisciplinary
Pierfrancesco Maltoni, Gianni Barucca, Bogdan Rutkowski, Maria Chiara Spadaro, Petra E. Jonsson, Gaspare Varvaro, Nader Yaacoub, Jose A. De Toro, Davide Peddis, Roland Mathieu
Summary: The magnetic coupling of SrFe12O19/CoFe2O4 nanocomposites is investigated. The structural coherence and texture at the interfaces of the nanostructures are evidenced by advanced electron microscopy. The exchange intergranular interaction is evidenced and the critical thickness for uniform reversal of coupled interfaces is quantified.
Article
Chemistry, Physical
Anna Komenda, Marek Wojnicki, Dzmitry Kharytonau, Grzegorz Mordarski, Edit Csapo, Robert P. Socha
Summary: Thin films of SnS were deposited on a copper substrate using a chemical bath method, and the effect of Na doping on the films was studied. SEM analysis showed that the films deposited at 80°C had a compact morphology, and the addition of a commercial surfactant resulted in rounded edges of the SnS grains. The thickness of the SnS layers on the copper substrate was found to be 230 nm, and the deposition parameters did not affect the thickness.
Article
Chemistry, Multidisciplinary
Melinda Szaloki, Istvan Csarnovics, Attila Bonyar, Ditta Ungor, Edit Csapo, Andras Sapi, Csaba Hegedus
Summary: This study investigates the plasmonic effect of gold-covered silica nanoparticles on the physicochemical and mechanical properties of dental resin. The results show that the application of patchy silica particles can improve the polymerization ratio and mechanical parameters of the composite.