Discovery of STRO-002, a Novel Homogeneous ADC Targeting Folate Receptor Alpha, for the Treatment of Ovarian and Endometrial Cancers

Phase III, randomized trial of mirvetuximab soravtansine versus chemotherapy in patients with platinum-resistant ovarian cancer: primary analysis of FORWARD I

(2021) K.N. Moore et al.   ANNALS OF ONCOLOGY

Antibody‐drug conjugate MORAb‐202 exhibits long‐lasting antitumor efficacy in TNBC PDx models

(2021) Keiji Furuuchi et al.   CANCER SCIENCE

Antibody‒drug conjugates: Recent advances in linker chemistry

(2021) Zheng Su et al.   Acta Pharmaceutica Sinica B

Endometrial Cancer

(2020) Karen H. Lu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ovarian Cancer: An Integrated Review

(2019) Christine Stewart et al.   Seminars in Oncology Nursing

RF1 attenuation enables efficient non-natural amino acid incorporation for production of homogeneous antibody drug conjugates

(2017) Gang Yin et al.   Scientific Reports

Intracellular Released Payload Influences Potency and Bystander-Killing Effects of Antibody-Drug Conjugates in Preclinical Models

(2016) F. Li et al.   CANCER RESEARCH

A Randomized, Double-Blind, Placebo-Controlled, Phase III Study to Assess Efficacy and Safety of Weekly Farletuzumab in Combination With Carboplatin and Taxane in Patients With Ovarian Cancer in First Platinum-Sensitive Relapse

(2016) Ignace Vergote et al.   JOURNAL OF CLINICAL ONCOLOGY

Mechanisms of Resistance to Antibody–Drug Conjugates

(2016) Frank Loganzo et al.   MOLECULAR CANCER THERAPEUTICS

Chemoresistance and targeted therapies in ovarian and endometrial cancers

(2016) Kevin Brasseur et al.   Oncotarget

Targeting folate receptor alpha for cancer treatment

(2016) Anthony Cheung et al.   Oncotarget

Targeting the folate receptor: diagnostic and therapeutic approaches to personalize cancer treatments

(2015) J. A. Ledermann et al.   ANNALS OF ONCOLOGY

Antibody-drug conjugates as novel anti-cancer chemotherapeutics

(2015) C. Peters et al.   BIOSCIENCE REPORTS

Production of Site-Specific Antibody–Drug Conjugates Using Optimized Non-Natural Amino Acids in a Cell-Free Expression System

(2014) Erik S. Zimmerman et al.   BIOCONJUGATE CHEMISTRY

In vitro Fab display: a cell-free system for IgG discovery

(2014) R. L. Stafford et al.   PROTEIN ENGINEERING DESIGN & SELECTION

In vivo mouse fluorescence imaging for folate-targeted delivery and release kinetics

(2014) Esther H. R. Tsai et al.   Biomedical Optics Express

Folate-receptor 1 (FOLR1) protein is elevated in the serum of ovarian cancer patients

(2013) F. Leung et al.   CLINICAL BIOCHEMISTRY

Folate receptor alpha as a tumor target in epithelial ovarian cancer

(2008) Kimberly R. Kalli et al.   GYNECOLOGIC ONCOLOGY