Bone morphogenetic protein-2 and bone therapy: successes and pitfalls

Routine use of recombinant human bone morphogenetic protein–2 in posterior fusions of the pediatric spine and incidence of cancer

(2015) Christina Sayama et al.   Journal of Neurosurgery-Pediatrics

Bone Regeneration Using Bone Morphogenetic Proteins and Various Biomaterial Carriers

(2015) Zeeshan Sheikh et al.   Materials

In silico Mechano-Chemical Model of Bone Healing for the Regeneration of Critical Defects: The Effect of BMP-2

(2015) Frederico O. Ribeiro et al.   PLoS One

Recombinant Human Bone Morphogenetic Protein-2 Confined by an Imperforate Titanium Shell over High-Profile Dental Implants in Rabbit Tibiae: A Pilot Bone Augmentation Study

(2014) Nardy Casap et al.   INTERNATIONAL JOURNAL OF ORAL & MAXILLOFACIAL IMPLANTS

Cancer Risk from Bone Morphogenetic Protein Exposure in Spinal Arthrodesis

(2014) Mick P Kelly et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

BMP-2 inhibits tumor-initiating ability in human renal cancer stem cells and induces bone formation

(2014) Lin Wang et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Recombinant Human Bone Morphogenetic Protein-2 Promote and Stabilize Hard and Soft Tissue Healing for Large Mandibular New Bone Reconstruction Defects

(2014) Marco Cicciù et al.   JOURNAL OF CRANIOFACIAL SURGERY

Exaggerated inflammatory environment decreases BMP-2/ACS-induced ectopic bone mass in a rat model: implications for clinical use of BMP-2

(2014) R.-L. Huang et al.   OSTEOARTHRITIS AND CARTILAGE

BMP-2 Promotes Oral Squamous Carcinoma Cell Invasion by Inducing CCL5 Release

(2014) Mi-joo Kim et al.   PLoS One

Effectiveness and Harms of Recombinant Human Bone Morphogenetic Protein-2 in Spine Fusion

(2013) Rongwei Fu et al.   ANNALS OF INTERNAL MEDICINE

Cancer Risk After Use of Recombinant Bone Morphogenetic Protein-2 for Spinal Arthrodesis

(2013) Eugene J Carragee et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

High-Dose rhBMP-2 for Adults: Major and Minor Complications

(2013) Addisu Mesfin et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Safety and Efficacy of Recombinant Human Bone Morphogenetic Protein 2 on Cranial Defect Closure in the Pediatric Population

(2013) Omar E. Beidas et al.   JOURNAL OF CRANIOFACIAL SURGERY

Risk of Cancer After Lumbar Fusion Surgery With Recombinant Human Bone Morphogenic Protein-2 (rh-BMP-2)

(2013) Gregory S. Cooper et al.   SPINE

Does Recombinant Human Bone Morphogenetic Protein-2 Use in Adult Spinal Deformity Increase Complications and Are Complications Associated With Location of rhBMP-2 Use? A Prospective, Multicenter Study of 279 Consecutive Patients

(2013) Shay Bess et al.   SPINE

Complications of rhBMP-2 utilization for posterolateral lumbar fusions requiring reoperation: a single practice, retrospective case series report

(2013) Martin F. Hoffmann et al.   Spine Journal

Recombinant human Bone Morphogenetic Protein-2 (rhBMP-2) in posterolateral lumbar spine fusion: complications in the elderly

(2013) Martin F Hoffmann et al.   Journal of Orthopaedic Surgery and Research

Adverse Events After Recombinant Human BMP2 in Nonspinal Orthopaedic Procedures

(2012) Emily Jane Woo   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Recombinant Human BMP-2 for the Treatment of Open Tibial Fractures

(2012) Shijun Wei et al.   ORTHOPEDICS

Recombinant Human Bone Morphogenetic Protein-2 as an Adjunct for Spine Fusion in a Pediatric Population

(2012) Muhammad M. Abd-El-Barr et al.   PEDIATRIC NEUROSURGERY

Effect of Escherichia coli-produced recombinant human bone morphogenetic protein 2 on the regeneration of canine segmental ulnar defects

(2011) Yasuji Harada et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Hyaline Cartilage Regeneration by Combined Therapy of Microfracture and Long-Term Bone Morphogenetic Protein-2 Delivery

(2011) Hee Seok Yang et al.   TISSUE ENGINEERING PART A

Improving Bone Formation in a Rat Femur Segmental Defect by Controlling Bone Morphogenetic Protein-2 Release

(2011) Kate V. Brown et al.   TISSUE ENGINEERING PART A

Difference in Soft Tissue Response Between Immediate and Delayed Delivery Suggests a New Mechanism for Recombinant Human Bone Morphogenetic Protein 2 Action in Large Segmental Bone Defects

(2011) Khaled A. Hussein et al.   TISSUE ENGINEERING PART A

Administration of Human Recombinant Bone Morphogenetic Protein-2 for Spine Fusion May Be Associated With Transient Postoperative Renal Insufficiency

(2010) Jonathan M. Latzman et al.   SPINE

Slow-Release Human Recombinant Bone Morphogenetic Protein-2 Embedded Within Electrospun Scaffolds for Regeneration of Bone Defect: In Vitro and In Vivo Evaluation

(2010) Samer Srouji et al.   TISSUE ENGINEERING PART A

Evaluation of Maxillary Alveolar Reconstruction Using a Resorbable Collagen Sponge with Recombinant Human Bone Morphogenetic Protein-2 in Cleft Lip and Palate Patients

(2010) Nivaldo Alonso et al.   TISSUE ENGINEERING PART C-METHODS

Complications of Recombinant Human BMP-2 for Treating Complex Tibial Plateau Fractures: A Preliminary Report

(2009) Sreevathsa Boraiah et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Bone morphogenetic proteins and tissue engineering: future directions

(2009) G.M. Calori et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Clinical and Radiographic Analysis of an Optimized rhBMP-2 Formulation as an Autograft Replacement in Posterolateral Lumbar Spine Arthrodesis

(2009) John R Dimar et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Influence of Residual Bone on Recombinant Human Bone Morphogenetic Protein-2–Induced Periodontal Regeneration in Experimental Periodontitis in Dogs

(2009) Akira Saito et al.   JOURNAL OF PERIODONTOLOGY

Silk Fibroin Microparticles as Carriers for Delivery of Human Recombinant Bone Morphogenetic Protein-2: In Vitro and In Vivo Bioactivity

(2009) Paulo César Bessa et al.   TISSUE ENGINEERING PART C-METHODS

Concepts in gene therapy for cartilage repair

(2008) Andre F. Steinert et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED