Sandwich-Cultured Hepatocytes as a Tool to Study Drug Disposition and Drug-Induced Liver Injury

Published 2016 View Full Article

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Title
Sandwich-Cultured Hepatocytes as a Tool to Study Drug Disposition and Drug-Induced Liver Injury
Authors
Keywords
sandwich-cultured hepatocytes (SCH), hepatic clearance, hepatobiliary disposition, bile acid transporters, toxicity, mathematical models
Journal
JOURNAL OF PHARMACEUTICAL SCIENCES
Volume 105, Issue 2, Pages 443-459
Publisher
Elsevier BV
Online
2016-01-30
DOI
10.1016/j.xphs.2015.11.008

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