Application of a Human Intestinal Epithelial Cell Monolayer to the Prediction of Oral Drug Absorption in Humans as a Superior Alternative to the Caco-2 Cell Monolayer

Published 2016 View Full Article

Title

Application of a Human Intestinal Epithelial Cell Monolayer to the Prediction of Oral Drug Absorption in Humans as a Superior Alternative to the Caco-2 Cell Monolayer

Authors

Keywords

intestinal absorption, membrane conductance and resistance, paracellular transport, permeability, tight junction, transcellular transport, ABC transporters, cell culture, intestinal epithelia

Journal

JOURNAL OF PHARMACEUTICAL SCIENCES

Volume 105, Issue 2, Pages 915-924

Publisher

Elsevier BV

Online

2016-01-30

DOI

10.1016/j.xphs.2015.11.035

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