Population Pharmacokinetic–Toxicodynamic Modeling and Simulation of Cisplatin-Induced Acute Renal Injury in Rats: Effect of Dosing Rate on Nephrotoxicity

Title
Population Pharmacokinetic–Toxicodynamic Modeling and Simulation of Cisplatin-Induced Acute Renal Injury in Rats: Effect of Dosing Rate on Nephrotoxicity
Authors
Keywords
cisplatin, nephrotoxicity, population pharmacokinetics/pharmacodynamics, pharmacokinetic/pharmacodynamic models, toxicokinetics, simulations, cancer chemotherapy
Journal
JOURNAL OF PHARMACEUTICAL SCIENCES
Volume 105, Issue 1, Pages 324-332
Publisher
Elsevier BV
Online
2015-12-23
DOI
10.1016/j.xphs.2015.10.022

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