Alteration in Intrapulmonary Pharmacokinetics of Aerosolized Model Compounds Due to Disruption of the Alveolar Epithelial Barriers Following Bleomycin-Induced Pulmonary Fibrosis in Rats

Title
Alteration in Intrapulmonary Pharmacokinetics of Aerosolized Model Compounds Due to Disruption of the Alveolar Epithelial Barriers Following Bleomycin-Induced Pulmonary Fibrosis in Rats
Authors
Keywords
idiopathic pulmonary fibrosis, aerosol-based pulmonary drug delivery system, anti-fibrotic agent, tight junction, claudin, alveolar epithelial cells, epithelial-mesenchymal transition
Journal
JOURNAL OF PHARMACEUTICAL SCIENCES
Volume 105, Issue 3, Pages 1327-1334
Publisher
Elsevier BV
Online
2016-01-30
DOI
10.1016/j.xphs.2015.12.010

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