Evaluation of Heavy-Chain C-Terminal Deletion on Product Quality and Pharmacokinetics of Monoclonal Antibodies

Published 2016 View Full Article

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Title
Evaluation of Heavy-Chain C-Terminal Deletion on Product Quality and Pharmacokinetics of Monoclonal Antibodies
Authors
Keywords
mAb, charge heterogeneity, C-terminal Lys deletion, Lys and Gly deletion, pharmacokinetics, bioavailability
Journal
JOURNAL OF PHARMACEUTICAL SCIENCES
Volume 105, Issue 7, Pages 2066-2072
Publisher
Elsevier BV
Online
2016-06-02
DOI
10.1016/j.xphs.2016.04.027

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