Validation of UHPLC–MS/MS methods for the determination of kaempferol and its metabolite 4-hydroxyphenyl acetic acid, and application to in vitro blood-brain barrier and intestinal drug permeability studies

Title
Validation of UHPLC–MS/MS methods for the determination of kaempferol and its metabolite 4-hydroxyphenyl acetic acid, and application to in vitro blood-brain barrier and intestinal drug permeability studies
Authors
Keywords
Kaempferol, 4-HPAA, LC–MS/MS, Method validation, Caco-2 model, Blood-brain barrier
Journal
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Volume 128, Issue -, Pages 264-274
Publisher
Elsevier BV
Online
2016-05-25
DOI
10.1016/j.jpba.2016.05.039

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