Article
Chemistry, Inorganic & Nuclear
Shubhangi N. Kotkar, Subedar Prasad, Gunwant P. Gadekar, Suresh B. Rewatkar
Summary: Natural sunlight active zinc oxide nanoparticles were synthesized using a simple solution auto combustion method. The structural and optical characteristics of the nanoparticles were studied, and it was found that they exhibited excellent photodegradation activity and antimicrobial properties.
INORGANIC CHEMISTRY COMMUNICATIONS
(2022)
Article
Materials Science, Multidisciplinary
Sheraz Yousaf, Sonia Zulfiqar, Muhammad Imran Din, Philips O. Agboola, Mohamed F. Aly Aboud, Muhammad Farooq Warsi, Imran Shakir
Summary: The study synthesized ZnO-NiO/rGO nano-hybrid for photocatalytic degradation of organic pollutants, with characterization showing excellent efficiency in degradation, making it a durable candidate in the field of catalysis.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2021)
Article
Environmental Sciences
Nadeem Raza, Waseem Raza, Hajera Gul, Ki-Hyun Kim
Summary: The novel heterostructured photocatalyst (ZnO-ZnTe) exhibit efficient photocatalytic performance for the removal of azo dye, showing high potential as a cost-effective and green remediation technique in water treatment processes.
ENVIRONMENTAL RESEARCH
(2021)
Article
Environmental Sciences
Sobia Maqbool, Adeel Ahmed, Arif Mukhtar, Muhammad Jamshaid, Aziz Ur Rehman, Saima Anjum
Summary: This work aims to develop a highly efficient solar light-induced photocatalyst based on La-Mn co-doped Fe2O3 nanoparticles. The synthesized nanoparticles were analyzed for their morphological, structural, and magnetic characteristics. The photocatalytic performance of the different catalysts was evaluated, and it was found that La0.2Mn0.2Fe1.6O3 catalyst showed exceptional degradation performance.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Materials Science, Multidisciplinary
Vy Anh Tran, Thanh Khoa Phung, Van Thuan Le, The Ky Vo, Tan Tai Nguyen, Thi Anh Nga Nguyen, Dinh Quoc Viet, Vu Quang Hieu, Thu-Thao Thi Vo
Summary: In this study, in-situ CoZn-MOF nanoparticles were converted into Co3O4-ZnO nano-size by calcination. The photocatalytic activity of Co3O4-ZnO NPs was demonstrated by the complete degradation of methyl orange under solar light. The catalyst showed significant stability and recyclability for four catalytic cycles.
Article
Automation & Control Systems
Chao-Hwa Liu, Cheng-Yu Huang, Po-Ching Lee, Guan-Chen Chen, Zheng-Rong Yang, Ching-Bin Lin
Summary: The innovative 3D printing procedure developed an AgCl/Ag-0 photocatalytic module through selective laser melting, which effectively degraded azo dye and sterilized E. coli. The optimal laser power and scanning speed for constructing the module were determined to be 26 W and 385 mm/s. The degradation kinetics of both azo dye and E. coli were first-order reactions, and the photocatalytic module exhibited durability and reliability even after multiple cycles of use.
INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY
(2021)
Article
Engineering, Environmental
Licheng Sang, Weiyi Yang, Shuang Gao, Suhua Li, Jian Ku Shang, Qi Li
Summary: This study discovered a new type of organic semiconductor-based photocatalyst, polyacrylonitrile (PAN), which has good light absorption and appropriate electronic band structure to degrade organic pollutants and disinfect bacteria under simulated solar illumination. The PAN photocatalyst shows good stability, reusability, and suitability for practical application in real water matrix, especially as wearable products with self-disinfection property.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Liyun Yan, Jiahui Tang, Qing-an Qiao, Honglan Cai, Yuqi Dong, Juan Jin, Yanbin Xu, Hongwei Gao
Summary: A series of Bi2MoO6/ZnO composite photocatalysts with different mass ratios were prepared using the hydrothermal method and characterized by various analysis techniques. The Bi2MoO6/ZnO composite catalyst exhibited twice the degradation rate constant compared to traditional ZnO photocatalysis. The composite catalyst also showed stable performance after multiple runs. The high photocatalytic activity of Bi2MoO6/ZnO was attributed to efficient electron transport and reduced carrier recombination near the heterojunction. The Bi2MoO6/ZnO nanocomposites have potential applications in photodegradation.
Article
Materials Science, Multidisciplinary
Amel Muhson Naji, Intisar Yahiya Mohammed, Safa H. Mohammed, Mustafa K. A. Mohammed, Duha S. Ahmed, Majid S. Jabir, Ahmed Mahdi Rheima
Summary: Adding polyvinyl alcohol to fluorine-doped zinc oxide nanoparticles can improve their photocatalytic activity. The fluorine-doped zinc oxide nanoparticles were synthesized through a co-precipitation reaction and then coated with different amounts of polyvinyl alcohol. The highest photocatalytic activity of the hybrid nanoparticles was achieved when the weight ratio of polyvinyl alcohol to zinc oxide nanoparticles was fixed at 4% during synthesis.
Article
Environmental Sciences
Lianxin Yuan, Weixuan Liu, Wanting Zhang
Summary: Element doping is an effective method for enhancing the photocatalytic performance of photocatalysts. This study utilized potassium sorbate as a new precursor to dope potassium ions into g-C3N4 during the calcination process, resulting in the formation of potassium-doped g-C3N4 (KCN). Through various characterization techniques and electrochemical measurements, it was found that potassium doping efficiently modified the band structure of g-C3N4, enhancing light absorption and conductivity, which accelerated charge transfer and photogenerated carrier separation. These findings demonstrate the potential of potassium incorporation in g-C3N4 for fabricating high-performance photocatalysts for organic pollutant removal.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Manjiri A. Mahadadalkar, Ganesh Dhakal, Sumanta Sahoo, Deivasigamani Ranjith Kumar, Marjorie Lara Baynosa, Van Quang Nguyen, Mostafa Saad Sayed, Abdelrahman M. Rabie, Woo Kyoung Kim, Jae-Jin Shim
Summary: In this study, a TiO2/In2S3 heterojunction composite photocatalyst was successfully prepared through a simple low-temperature hydrothermal method. The composite showed excellent photocatalytic degradation performance for Rhodamine B under solar light irradiation, with a degradation rate of 99.9% in just 20 minutes. The environmentally friendly synthesis process and high stability make the TiO2/In2S3 composite a promising candidate for cost-effective wastewater treatment.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2023)
Article
Biochemical Research Methods
Rania Farouq, Ehsan Kh Ismaeel, Aliaa M. Monazie
Summary: This study investigates the photocatalytic degradation potential of ZnO nanoparticles for Eosin dye and examines the influence of parameters such as flow rate, pH, catalyst dose, and dye concentration. By using the Box-Behnken design under the Response Surface Methodology, optimal values for catalyst amount, dye concentration, and flow rate were obtained, leading to the highest degradation efficiency.
JOURNAL OF FLUORESCENCE
(2022)
Article
Materials Science, Ceramics
H. Bahiraei, S. Azarakhsh, S. Ghasemi
Summary: This study investigates the photocatalytic activity of magnetic CoFe2O4/g-C3N4/ZnO (CF-gCN/ZnO) nanocomposite as a visible-light photocatalyst. The heterojunction CF-gCN/ZnO photocatalyst achieved a photodegradation efficiency of 89% for degradation of methylene blue (MB) after 100 min of irradiation. The formation of heterojunction structures at the interface of g-C3N4 and ZnO leads to improved photocatalytic activity due to the separation of the photo-generated electron-hole pairs.
CERAMICS INTERNATIONAL
(2023)
Article
Engineering, Chemical
Seddigheh Kohansal, Mohammad Haghighi, Mahdi Zarrabi
Summary: A Bi7O9I3-ZnO nanocomposite was designed using a simple sono-dispersion method, with the influence of ultrasound power investigated. The photocatalysts showed promising degradation efficiency for methylene blue, with the highest efficiency achieved at a power of 300. Ultrasound irradiation had a positive effect on the photocatalyst activity, influencing properties such as crystallite size, crystallinity, and nanoparticle dispersion.
CHEMICAL ENGINEERING SCIENCE
(2021)
Article
Materials Science, Ceramics
M. Pavithra, M. B. Jessie Raj
Summary: The study successfully synthesized lead-doped zinc oxide nanocomposites by varying ultrasonication time, altering the crystallite size and forming Pb/ZnO bonds. The nanocomposites showed excellent antibacterial activity and photocatalytic degradation of dyes.
CERAMICS INTERNATIONAL
(2021)
Article
Biochemistry & Molecular Biology
Eslam B. Elkaeed, Reda G. Yousef, Hazem Elkady, Ahmed B. M. Mehany, Bshra A. Alsfouk, Dalal Z. Husein, Ibrahim M. Ibrahim, Ahmed M. Metwaly, Ibrahim H. Eissa
Summary: A new naphthalene analog (compound 7) designed and synthesized demonstrated high inhibitory potential against VEGFR-2, with proper binding and energy compared to sorafenib in molecular docking studies. Various experiments confirmed the accurate interaction of compound 7 with VEGFR-2 and its drug-likeness.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Biochemical Research Methods
Bharti Jain, Rajeev Jain, Rakesh Roshan Jha, Abhishek Ghosh, Debasish Basu, Mohammad A. S. Abourehab, Atul Bajaj, Vimukti Chauhan, Sukhminder Kaur, Shweta Sharma
Summary: This study explores the use of unmodified laboratory filter paper as a sorbent for extraction and analysis of nine drugs from human blood samples using gas chromatography-mass spectrometry (GC-MS). The method, called cellulose paper sorptive extraction (CPSE), involves adsorption of the target analytes on the filter paper followed by elution into methanol. Multivariate optimization was used to screen and optimize factors for CPSE. The method is cost-effective, environmentally friendly, and has satisfactory recovery rates. It has potential applications in analyzing drugs in blood samples.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2023)
Article
Spectroscopy
Ahmed H. Abdelazim, Mohammed A. S. Abourehab, Lobna M. Abd Elhalim, Ahmed A. Almrasy, Sherif Ramzy
Summary: Molnupiravir is an oral antiviral drug that shows significant benefits in reducing hospitalizations or deaths in mild COVID-19. A green computational spectrophotometric method was developed to determine the concentration of molnupiravir. Theoretical calculations were performed to determine the best coupling agent for efficient diazo coupling of molnupiravir, with 8-hydroxyquinoline showing the highest interaction.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Nanoscience & Nanotechnology
Abeer S. Hassan, Amal Hofni, Mohammed A. S. Abourehab, Iman A. M. Abdel-Rahman
Summary: This study aimed to develop transethosomes as a nanovehicle to enhance the transdermal delivery of ginger extract (GE). The selected formulation of GE-loaded transethosomes showed appropriate particle size, zeta-potential, and encapsulation efficiency. The transethosomal hydrogel demonstrated sustained drug release and improved skin permeation and anti-inflammatory effects compared to free GE hydrogel.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2023)
Article
Chemistry, Multidisciplinary
M. Tariq Qamar, Shahid Iqbal, M. Aslam, Ahmad Alhujaily, Anum Bilal, Komal Rizwan, Hafiz Muhammad Umer Farooq, Tahir Ali Sheikh, Ali Bahadur, Nasser S. Awwad, Hala A. Ibrahium, Rasmiah S. Almufarij, Eslam B. Elkaeed
Summary: In this study, economical indoor white light was used as the illumination source for the photocatalytic removal of organic toxins from contaminated water. CeO2 was doped with Ni, Cu, and Fe to enhance its catalytic activity. Fe-doped CeO2 exhibited the highest photocatalytic activity among all the materials tested. The antifungal properties of the doped CeO2 nanoparticles were also assessed, and Fe-doped CeO2 nanoparticles showed outstanding antifungal properties compared to other doped CeO2 nanoparticles.
FRONTIERS IN CHEMISTRY
(2023)
Article
Chemistry, Medicinal
Moataz A. Shaldam, Ahmed F. Khalil, Hadia Almahli, Maiy Y. Jaballah, Andrea Angeli, Eman F. Khaleel, Rehab Mustafa Badi, Eslam B. Elkaeed, Claudiu T. Supuran, Wagdy M. Eldehna, Haytham O. Tawfik
Summary: New 5-cyano-6-oxo-pyridine-based sulfonamides were designed and synthesized to potentially inhibit both EGFR and CA, with anticancer properties. The inhibitory effects on EGFR were observed, while the inhibitory effects on CA were affected by the neighboring methoxy group.
ARCHIV DER PHARMAZIE
(2023)
Article
Engineering, Electrical & Electronic
Muhammad Amjad, Ayesha Mohyuddin, Mohsin Javed, Shahid Iqbal, Rabia Liaquat, Mohammed T. Alotaibi, Wajad Ulfat, Randa A. Althobiti, Eman Alzahrani, Abd-ElAziem Farouk, Murefah Mana Al-Anazy, Eslam B. Elkaeed
Summary: Researchers developed a biodegradable starch-based polymer and silver blend nanocomposite for efficient removal of hazardous organic dyes from industrial wastewater.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
(2023)
Article
Chemistry, Physical
Sumera Zaib, Aliya Ibrar, Imtiaz Khan, Nehal Rana, Rosa M. Gomila, Christopher John McAdam, Abdulaziz A. Al-Askar, Eslam B. Elkaeed, Antonio Frontera
Summary: In this study, a tricyclic aromatic structure, tetrahydrocarbazole (THC), with a nitrile functionality was synthesized, and the noncovalent interactions in the crystal structure of THC were investigated using experimental and theoretical methods. The results showed the presence of extensive N-H...O and O-H...N hydrogen bonds as well as weaker 2r...2r and C-H...2r contacts in the supramolecular assembly of THC. Furthermore, THC exhibited strong inhibitory potential against urease activity. Rating: 8 points.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Chemistry, Multidisciplinary
Shoaib Khan, Shahid Iqbal, Wajid Rehman, Nadia Hussain, Rafaqat Hussain, Mazloom Shah, Farhan Ali, Ahmed M. Fouda, Yousaf Khan, Ayed A. Dera, Mohammed Issa Alahmdi, Ali Bahadur, Hanan A. Al-ghulikah, Eslam B. Elkaeed
Summary: Different synthetic methods have been developed recently to investigate the biological significances of bis-benzimidazole analogs. This study aimed to synthesize a new series of bis-benzimidazole analogs using a fast and efficient method. Spectroscopic techniques were used to confirm the synthesized scaffolds, and molecular docking was performed to analyze the binding interactions. The derivatives were evaluated for their inhibitory activity against α-amylase and α-glucosidase through SAR study. Compound 9 exhibited excellent activity compared to the referenced drug acarbose.
ARABIAN JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Rabia Akram Bajwa, Umar Farooq, Shafiq Ullah, Muhammad Salman, Sabah Haider, Shabnam Shahida, Bilal Ahmad Farooqi, Eslam B. Elkaeed
Summary: A three-dimensional hollow metal organic framework (MOF-199) was coated on the active surface of graphene oxide (GO) using a layer-by-layer coating method, resulting in hybrid anodic materials with high porosity and low charge resistance. The coated cupric acetate and benzene-1,3,5-tricarboxylic acid [Cu3(BTC)2] enhanced structural diversity and reduced the synergistic effect for lithium ion batteries.
JOURNAL OF SAUDI CHEMICAL SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Souad A. El-Metwally, Hazem Elkady, Mohamed Hagras, Dalal Z. Husein, Ibrahim M. Ibrahim, Mohammed S. Taghour, Hesham A. El-Mahdy, Ahmed Ismail, Bshra A. Alsfouk, Eslam B. Elkaeed, Ahmed M. Metwaly, Ibrahim H. Eissa
Summary: Novel thieno[2,3-d]pyrimidine-derived compounds were designed and synthesized to target VEGFR-2, exhibiting potential anticancer activities. Compound 18 displayed the strongest anti-VEGFR-2 potential with excellent proliferative effects against MCF-7 and HepG2 cancer cell lines. Computational techniques were used to investigate the molecular interactions of the VEGFR-2-18 complex and provided valuable insights for future drug design efforts. This study highlights the potential of thieno[2,3-d]pyrimidine derivatives as anticancer agents and lays a foundation for further research in this area.
Article
Chemistry, Multidisciplinary
Ibrahim H. H. Eissa, Reda G. G. Yousef, Hazem Elkady, Eslam B. B. Elkaeed, Aisha A. A. Alsfouk, Dalal Z. Z. Husein, Ibrahim M. M. Ibrahim, Mostafa A. A. Elhendawy, Murrell Godfrey, Ahmed M. M. Metwaly
Summary: This study aimed to design theobromine derivatives that can inhibit VEGFR-2, a protein involved in cancer progression. The new compounds were tested in vitro against two cancer cell lines, MCF-7 and HepG2, and compound 15a showed the highest effectiveness. 15a demonstrated potent VEGFR-2 inhibitory activity and induced apoptosis in HepG2 cells, making it a promising lead compound for the development of a novel anticancer agent.
Article
Engineering, Chemical
Yu Shuang Ren, Hizbullah Khan, Bushra Khan, Muhammad Ilyas, Shahid Iqbal
Summary: The adsorption of aluminum (Al3+) from aqueous solutions using eucalyptus wood waste-derived biochar (EWB) was studied. The EWB morphology and structure were analyzed. Variables influencing adsorption performance were analyzed. The EWB showed high adsorption capacity for Al3+ due to its porous structure and high adsorption rate in low concentration solutions.
DESALINATION AND WATER TREATMENT
(2023)
Article
Materials Science, Multidisciplinary
Tanzeela Fazal, Shahid Iqbal, Mujaddad-ur Rehman, Azam Hayat, Mazloom Shah, Sajid Mahmood, Khurram Shoaib, Ahmad Alhujaily, Bibi Nazia Murtaza, Sedra tul Muntaha, Randa A. Althobiti, Eman Alzahrani, Abd-ElAziem Farouk, Foziah F. Al-Fawzan, Eslam B. Elkaeed
Summary: Biological production of nanomaterials is an environmentally friendly and stable approach. In this study, silver iron oxide nanoparticles were synthesized using Escherichia coli bacterium, showing antimicrobial and photocatalytic degradation properties, as well as hydrogen generation potential.
MATERIALS CHEMISTRY AND PHYSICS
(2024)
Article
Chemistry, Physical
Xinlei Chen, Shiyi Chen, Xuele Lin, Jingxuan Zhou, Xingjun Gao, Yaoqi Zhen, Xiaodan Ma, Shouwen Jin, Linfang Shi, Hui Liu, Daqi Wang
Summary: Nine mixed-ligand Cd2+ complexes with different geometric structures were synthesized and characterized. The complexes exhibit various coordination modes and form both intra- and intermolecular hydrogen bonds.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Rupali Mahajan, Abhishek Sharma, Bhagyashree Patra, Lijo Mani, Parul Grover, Sandeep Kumar, Santosh Kumar Guru, Gananadhamu Samanthula, Amol G. Dikundwar, Amit Asthana
Summary: This research article provides a comprehensive characterization and toxicological assessment of a photoisomeric impurity of the antianemic drug Roxadustat. The impurity has a distinct structure compared to the drug and its formation due to light exposure is a concern. Through various experiments, including single crystal XRD, physicochemical characterization, and in vitro cytotoxicity assays, the researchers confirmed the structure of the impurity, evaluated its conversion with Roxadustat, and assessed its toxicological activity. These findings contribute to the understanding of drug stability, safety, and formulation development.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Laila S. Alqarni, Azzah M. Alghamdi, Nuha Y. Elamin, A. Rajeh
Summary: The solution casting method was used to produce a new type of nanocomposites made of chitosan, gelatin, and co-doped ZnO nanoparticles. The addition of 3.5% co-doped ZnO nanoparticles improved the physicochemical characteristics and antimicrobial effects of the nanocomposites, indicating their significant potential in food packaging and energy storage.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Ruchi Gaur
Summary: The structure and intermolecular interactions of a newly synthesized bis-chalcone THXA were studied using experimental and computational methods. The importance of non-covalent interactions such as pi center dot center dot center dot pi, C-H center dot center dot center dot S, and C-H center dot center dot center dot pi was revealed.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Andrii Bazylevich, Leonid Patsenker, Sarit Aviel-Ronen, Gary Gellerman
Summary: Drug combination therapy is commonly used for treating various skin disorders, but its effectiveness is often limited. In this study, researchers synthesized conjugates of anti-pigmenting drugs and hyaluronic acid (HA) to improve treatment efficacy. These HA-drug conjugates exhibited measurable drug release profiles and demonstrated superior depigmentation effects compared to control groups in a swine model.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Xiaodan Ma, Xinlei Chen, Yaoqi Zhen, Xunjie Zheng, Chengzhe Shi, Shouwen Jin, Bin Liu, Bin Chen, Daqi Wang
Summary: Cocrystallization experiments between minoxidil and aryl acids coformers resulted in the successful formation of multi-component samples. The nature of these samples was determined using various techniques and their structural and supramolecular aspects were investigated. The outcomes revealed the importance of nonbonding contacts and different types of interactions in stabilizing and expanding the crystal structures.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Najla A. Alshaye, Magdy A. Ibrahim, Al-Shimaa Badran
Summary: The chemical behavior of 3-substituted-6,8-dimethylchromones towards phenylhydrazine was examined. Different reaction conditions produced various products, and the molecular geometries and reactivity descriptors of the compounds were also investigated. The results suggest that these compounds are suitable for nonlinear optical applications.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Hayette Alliouche, Houria Bouria, Rafik Bensegueni, Mounia Guergouri, Abdelmalek Bouraiou, Ali Belfaitah
Summary: In this paper, a combined experimental and theoretical study was conducted to synthesize and characterize new 2-quinolone-piperidine and -morpholine hybrids. The results from experiments were validated using computational calculations, and the affinity between these compounds and Acetylcholinesterase/Butyrylcholinesterase was estimated through molecular docking.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Wei-Min Chen, Juan-Juan Shao, Yi Zhang, Zhen-Dong Xue, Peng-Lai Liu, Jian-Ling Ni, Li-Zhuang Chen, Qiang Gao, Fang-Ming Wang
Summary: This study synthesized and characterized a novel Mn-based LMOF, and achieved good results in detecting heavy metal Al3+ in water, showing good stability, high selectivity and sensitivity. This provides new insights into the potential applications of Mn-based MOFs in chemical sensing.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Jun-Xia Li, Yi-Jing Lu, Ke-Ying Quan, Li-Bing Wu, Xun Feng, Wei-Zhou Wang
Summary: This study synthesized two cobalt(II) complexes and analyzed their crystal structures using single-crystal X-ray diffraction. The results showed that the crystal structures of these complexes were different, and they exhibited different crystal packing and magnetic properties.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Yang Li, Yan Zhang, Hong Xu, Min Li, Zhen Li, Zi-yu Song, Ji-shi Chen, Yan-Jun Liu, Yong Sun, Zhao Yang
Summary: This study reports the synthesis and solid-state characterization of a new pharmaceutical cocrystal, PRO-BPE, which can enhance the solubility of the highly water-insoluble prodrug probenecid. The PRO-BPE cocrystals were found to have superior water solubility compared to pure PRO. This research provides valuable insights into improving the solubility of poorly soluble drugs.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Lucas G. B. Felicio, Bianca B. M. Vieira, Ivana S. Lula, Renata Diniz, Frank Alexis, Flavio B. Miguz, Frederico B. De Sousa
Summary: A novel spiropyran derivative was synthesized for heavy metals sensing in water. The results demonstrated that the new derivative can serve as a rapid, sensitive, and simple tool for detecting Hg2+ ions in water with high selectivity.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Junqing Meng, Jie Wang, Lijuan Wang, Chunhui Lyu, Haiyan Chen, Yingpei Lyu, Baisheng Nie
Summary: Material modification with low surface energy can achieve lower surface free energy on micro-and nano-rough structures, which is crucial for developing superhydrophobic surfaces. In this study, attapulgite (APT) was modified with alkylamine, alkylammonium salt, and stearic acid, and the interaction between low surface materials and attapulgite was explained. The results showed that the hydrophobicity of APT was significantly modified by the modifiers, and the surface free energy of the composites first decreased and then increased with increasing molecular number of low surface energy monomers.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Karan Goswami, Dipak Das, Parthasarathi Bera, Sounak Roy, Md. Motin Seikh, Prasanta Kumar Sinha, Arup Gayen
Summary: This work presents the development of a simple and highly active heterogeneous Pd catalyst for Suzuki-Miyaura carbon-carbon cross-coupling reaction. The NiPdFe-1 catalyst shows the best activity and stability among the prepared catalysts. It efficiently promotes the coupling reaction between aryl bromide and phenyl boronic acid under mild reaction conditions with high isolated yields.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Ekta Pardhi, Devendra Singh Tomar, Rahul Khemchandani, Gananadhamu Samanthula, Pankaj Kumar Singh, Neelesh Kumar Mehra
Summary: The main aim of this study was to prepare a drug-drug coamorphous system to improve the physiochemical properties, solubility and stability of Apremilast and Indomethacin. Various solid-state characterization techniques were used to characterize the prepared system. Molecular level interactions were studied using molecular modeling and ATR-FTIR and 1H NMR. Solubility and dissolution studies showed the benefits of the coamorphous system. The system was found to be stable for a period of five months. Permeation study also demonstrated improved flux for both drugs compared to their crystalline forms. The coamorphous system showed anti-psoriatic and anti-melanogenic activity based on molecular docking results. Overall, the developed CAM-based supersaturated system exhibited improved physicochemical properties and physical stability.
JOURNAL OF MOLECULAR STRUCTURE
(2024)