Article
Polymer Science
Hang Xiao, Quan-Xi Shi, Min Su, Xiao-Li Sun, Hongli Bao, Wen-Ming Wan
Summary: This study demonstrates a one-pot strategy for the molecular design of stimuli-responsive opposite emission/absorption polymer material with unique properties. The nontraditional intrinsic luminescence in the visible region is achieved through reversible addition-fragmentation chain transfer polymerization-induced emission (PIE) of a specific moiety. The opposite emission/absorption properties are derived from the carbocation-quinoid mechanism, enabling fluorescence encryption capability. This work provides a proof of concept for a novel polymer material that might inspire different fields.
Article
Chemistry, Multidisciplinary
Qian Yan, Renjie Ding, Haowen Zheng, Pengyang Li, Zonglin Liu, Zhong Chen, Jinhua Xiong, Fuhua Xue, Xu Zhao, Qingyu Peng, Xiaodong He
Summary: An anisotropic photo-responsive conductive hydrogel is designed by a directional freezing method, which exhibits enhanced mechanical properties and conductivity in a specific direction. With the ability to achieve rapid volume deswelling under light irradiation, the hydrogel actuator shows fast response and high driving strength, making it valuable for various applications.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Polymer Science
Sk Arif Mohammad, Devendra Kumar, Md Mehboob Alam, Sanjib Banerjee
Summary: This study presents a simple and cost-effective method for ultrafast and recyclable photo-induced polymerization in ionic liquids, yielding low dispersity polymers and well-defined diblock copolymers. The stimuli response of the copolymers to pH and temperature changes has been evaluated, showing potential applications in precise spatiotemporal control. Density functional theory (DFT) calculations rationalize the underlying mechanism of the polymerization process.
Article
Chemistry, Applied
Lakshmi Priya Datta, Triparna Mukherjee, Tapan Kumar Das
Summary: The rampant use of antibiotics and emergence of zoonotic diseases have led to serious global health hazards. Fungal infections, particularly those caused by Aspergillus species, are challenging due to their eukaryotic nature. Researchers have developed pH responsive cationic biocompatible polymers based on amino acids inspired by antimicrobial peptides, which have demonstrated effective fungicidal activities against Aspergillus niger. The mechanism of action involves inhibition of hyphal growth and distortion of conidiophores, with the aqueous solution properties of the side chain groups of individual amino acids significantly influencing the fungicidal activities.
REACTIVE & FUNCTIONAL POLYMERS
(2021)
Article
Polymer Science
Wojciech Raj, Krzysztof Jerczynski, Mahdi Rahimi, Ewa Pavlova, Miroslav Slouf, Agata Przekora, Joanna Pietrasik
Summary: In this study, a series of vitamin E-based TPGS-poly(2-(dimethylamino)ethyl methacrylate)-b-poly(3-vinyl benzaldehyde) block copolymer micelles were synthesized, and the anticancer drug DOX was loaded within the micelles. The micelles demonstrated potential as drug delivery systems for cancer treatment, with pH-responsive characteristics. However, increasing the hydrophobic block polymerization degree reduced the cytotoxicity of the micelles.
Article
Polymer Science
Arman Moini Jazani, Jung Kwon Oh
Summary: A new method for synthesizing multi-stimuli-responsive degradable block copolymers is reported in this study. The copolymer can achieve controlled, sustained, or rapid drug release through different stimuli (acid, reduction, light).
Review
Biochemistry & Molecular Biology
Chen Zhu, Julien Nicolas
Summary: Polymerization-induced self-assembly (PISA) and crystallization-driven self-assembly (CDSA) techniques are powerful approaches to produce synthetic nano-objects suitable for biomedical applications.
Article
Polymer Science
Aysun Degirmenci, Rana Sanyal, Mehmet Arslan, Amitav Sanyal
Summary: In this study, functional copolymers with activated disulfide groups as side chains were synthesized using RAFT polymerization, allowing for reversible thiol-based functionalization. These copolymers were used to create reactive coatings on glass surfaces, demonstrating successful reaction with model thiol-containing molecules.
Review
Biotechnology & Applied Microbiology
Di Chang, Yuanyuan Ma, Xiaoxuan Xu, Jinbing Xie, Shenghong Ju
Summary: Polymeric nanoparticles are widely used as carriers in medicine, especially in cancer therapy, due to their biocompatibility and ability to respond to stimuli conditions. Stimuli-responsive polymeric nanoplatforms have the potential to significantly improve the effectiveness of cancer treatment by changing physicochemical properties in target tissues.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Polymer Science
Cabell B. Eades, Joanna Korpanty, John B. Garrison, Georg M. Scheutz, Sofia L. Goodrich, Nathan C. Gianneschi, Brent S. Sumerlin
Summary: We present a dual-responsive block copolymer system that can control the size and morphology of self-assembled nanostructures through pH-dependent cloud point (Tcp). By incorporating a pH- and temperature-responsive monomer, 2-(dimethylamino)ethyl methacrylate (DMAEMA), in the nanoparticle corona, the relative hydrophilic/hydrophobic block volumes can be controlled. Varying the pH, temperature, and content of DMAEMA, we successfully generated micelles, worms, and vesicles from a single block copolymer composition.
Review
Chemistry, Multidisciplinary
Liuzhou Mao, Panqin Ma, Xi Luo, Hongwei Cheng, Zhanxiang Wang, Enyi Ye, Xian Jun Loh, Yun-Long Wu, Zibiao Li
Summary: The development of nanovaccines that use polymeric delivery carriers has gained significant attention for therapeutic treatment of cancer and infectious diseases. Stimuli-responsive polymeric nanocarriers have shown promise for targeted delivery of antigens and adjuvants, improving immune responses and immunotherapy. This review presents the recent advancements in stimulus-responsive polymer-based nanovaccines for immunotherapeutic applications and discusses strategies for future designs of multifunctional polymeric nanovaccines.
Article
Materials Science, Multidisciplinary
Nicolo Manfredini, Mattia Sponchioni, Davide Moscatelli
Summary: Thermo-responsive polymeric surfactants were synthesized to promote NP formation during eFRP and facilitate bulk polymer recovery by increasing temperature.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Multidisciplinary Sciences
Yu Zhu, Hanqiu Jiang, Weiwei Wu, Xiao-Qin Xu, Xu-Qing Wang, Wei-Jian Li, Wei-Tao Xu, GengXin Liu, Yubin Ke, Wei Wang, Hai-Bo Yang
Summary: This article presents a novel type of polymer, rotaxane-branched dendronized polymers, with tunable thermal and rheological properties. These polymers have reversible thickness modulation ability and can serve as attractive platforms for the construction of smart polymeric materials.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Katharina Leer, Gizem Cinar, Jana I. Solomun, Liam Martin, Ivo Nischang, Anja Traeger
Summary: Stimuli-responsive block copolymer micelles show promise for efficient gene delivery due to tailored properties. A system was designed using temperature and pH responsiveness, resulting in successful gene delivery. Core-crosslinking significantly increased transfection efficiency in this comprehensive investigation.
Article
Polymer Science
Krisada Auepattana-Aumrung, Treethip Phakkeeree, Daniel Crespy
Summary: Corrosion is a significant issue for metals and alloys, but can be reduced by adding corrosion inhibitors to coatings, leading to the development of polymer-corrosion inhibitor conjugates. Different fields of applications require different levels and types of metal protection, where beta-thiopropionate and ester linkages play a role in providing suitable protection for varying corrosion levels.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)