Exposure to the anti-microbial chemical triclosan disrupts keratinocyte function and skin integrity in a model of reconstructed human epidermis

Filaggrin Polymorphisms and the Uptake of Chemicals through the Skin—A Human Experimental Study

(2021) Emelie Rietz Liljedahl et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Dermal Exposure to the Immunomodulatory Antimicrobial Chemical Triclosan Alters the Skin Barrier Integrity and Microbiome in Mice

(2021) Rachel Baur et al.   TOXICOLOGICAL SCIENCES

Topical Application of the Antimicrobial Agent Triclosan Induces NLRP3 Inflammasome Activation and Mitochondrial Dysfunction

(2020) Lisa M Weatherly et al.   TOXICOLOGICAL SCIENCES

Cytokinocytes: the diverse contribution of keratinocytes to immune responses in skin

(2020) Yanyun Jiang et al.   JCI Insight

New insights into the cellular mechanism of triclosan-induced dermal toxicity from a combined metabolomic and lipidomic approach

(2020) Yanshan Liang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Epithelial barrier repair and prevention of allergy

(2019) Elena Goleva et al.   JOURNAL OF CLINICAL INVESTIGATION

Interleukin-36 in Infectious and Inflammatory Skin Diseases

(2019) Anna-Lena Buhl et al.   Frontiers in Immunology

Contribution of antimicrobials to the development of allergic disease

(2019) Stacey E Anderson et al.   CURRENT OPINION IN IMMUNOLOGY

3D skin models for 3R research: The potential of 3D reconstructed skin models to study skin barrier function

(2018) Hanna Niehues et al.   EXPERIMENTAL DERMATOLOGY

Triclosan-induced Alteration of Gut Microbiome and Aggravation of Asthmatic Airway Response in Aeroallergen-sensitized mice

(2018) R. Hirota et al.   ALLERGY

The Amino-Terminal Part of Human Filaggrin-2 is a Component of Cornified Envelopes

(2018) Géraldine Albérola et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Epidermal equivalents of filaggrin null keratinocytes do not show impaired skin barrier function

(2017) Hanna Niehues et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Topical application of the anti-microbial chemical triclosan induces immunomodulatory responses through the S100A8/A9-TLR4 pathway

(2017) Nikki B. Marshall et al.   Journal of Immunotoxicology

Triclosan exposure, transformation, and human health effects

(2017) Lisa M. Weatherly et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

The psoriasis-associated IL-17A induces and cooperates with IL-36 cytokines to control keratinocyte differentiation and function

(2017) Carolina M. Pfaff et al.   Scientific Reports

Skin barrier impairment at birth predicts food allergy at 2 years of age

(2016) Maeve M. Kelleher et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Triclosan promotes epicutaneous sensitization to peanut in mice

(2016) Steven Tobar et al.   Clinical and Translational Allergy

Barrier Epithelial Cells and the Control of Type 2 Immunity

(2015) Hamida Hammad et al.   IMMUNITY

Thymic stromal lymphopoietin downregulates filaggrin expression by signal transducer and activator of transcription 3 (STAT3) and extracellular signal-regulated kinase (ERK) phosphorylation in keratinocytes

(2015) Jin Hee Kim et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Skin barrier dysfunction measured by transepidermal water loss at 2 days and 2 months predates and predicts atopic dermatitis at 1 year

(2015) Maeve Kelleher et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Investigations of immunotoxicity and allergic potential induced by topical application of triclosan in mice

(2015) Stacey E. Anderson et al.   Journal of Immunotoxicology

Triclosan Induces Thymic Stromal Lymphopoietin in Skin Promoting Th2 Allergic Responses

(2015) Nikki B. Marshall et al.   TOXICOLOGICAL SCIENCES

In a three-dimensional reconstructed human epidermis filaggrin-2 is essential for proper cornification

(2015) V Pendaries et al.   Cell Death & Disease

Dose–response assessment of the dermal toxicity of triclosan in B6C3F1 mice

(2015) Jia-Long Fang et al.   Toxicology Research

Extracellular signal-regulated kinases 1/2 and Akt contribute to triclosan-stimulated proliferation of JB6 Cl 41-5a cells

(2014) Yuanfeng Wu et al.   ARCHIVES OF TOXICOLOGY

Knockdown of Filaggrin in a Three-Dimensional Reconstructed Human Epidermis Impairs Keratinocyte Differentiation

(2014) Valérie Pendaries et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Health Care Worker Exposures to the Antibacterial Agent Triclosan

(2014) Julia K. MacIsaac et al.   JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Urinary triclosan levels and recent asthma exacerbations

(2013) Jessica H. Savage et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Contribution of Tight Junction Proteins to Ion, Macromolecule, and Water Barrier in Keratinocytes

(2013) Nina Kirschner et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Epidermal morphogenesis during progressivein vitro3D reconstruction at the air-liquid interface

(2012) Aurélie Frankart et al.   EXPERIMENTAL DERMATOLOGY

Urinary levels of triclosan and parabens are associated with aeroallergen and food sensitization

(2012) Jessica H. Savage et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand–dependent terminal keratinocyte differentiation

(2012) Claus-Werner Franzke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Exposure to Triclosan Augments the Allergic Response to Ovalbumin in a Mouse Model of Asthma

(2012) Stacey E. Anderson et al.   TOXICOLOGICAL SCIENCES

Occurrence, Efficacy, Metabolism, and Toxicity of Triclosan

(2010) JIA-LONG Fang et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS

Knockdown of Filaggrin Impairs Diffusion Barrier Function and Increases UV Sensitivity in a Human Skin Model

(2010) Michael Mildner et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY