CanRisk-Prostate: A Comprehensive, Externally Validated Risk Model for the Prediction of Future Prostate Cancer

Enhancing the BOADICEA cancer risk prediction model to incorporate new data on RAD51C, RAD51D, BARD1 updates to tumour pathology and cancer incidence

(2022) Andrew Lee et al.   JOURNAL OF MEDICAL GENETICS

Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

(2021) David V. Conti et al.   NATURE GENETICS

Combined Effect of a Polygenic Risk Score and Rare Genetic Variants on Prostate Cancer Risk

(2021) Burcu F. Darst et al.   EUROPEAN UROLOGY

Evaluation of a Multiethnic Polygenic Risk Score Model for Prostate Cancer

(2021) Anna Plym et al.   JNCI-Journal of the National Cancer Institute

Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank

(2021) Joseph D. Szustakowski et al.   NATURE GENETICS

BRCA1 and BRCA2 pathogenic variants and prostate cancer risk: systematic review and meta-analysis

(2021) Tommy Nyberg et al.   BRITISH JOURNAL OF CANCER

A prospective prostate cancer screening programme for men with pathogenic variants in mismatch repair genes (IMPACT): initial results from an international prospective study

(2021) Elizabeth K Bancroft et al.   LANCET ONCOLOGY

Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers

(2020) Nina Mars et al.   NATURE MEDICINE

Prostate Cancer Risk by BRCA2 Genomic Regions

(2020) Tommy Nyberg et al.   EUROPEAN UROLOGY

Germline HOXB13 G84E mutation carriers and risk to twenty common types of cancer: results from the UK Biobank

(2020) Jun Wei et al.   BRITISH JOURNAL OF CANCER

Prostate Cancer Incidence and Survival, by Stage and Race/Ethnicity — United States, 2001–2017

(2020) David A. Siegel et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Performance of Three Inherited Risk Measures for Predicting Prostate Cancer Incidence and Mortality: A Population-based Prospective Analysis

(2020) Zhuqing Shi et al.   EUROPEAN UROLOGY

BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors

(2019) Andrew Lee et al.   GENETICS IN MEDICINE

Germline DNA Repair Gene Mutations in Young-onset Prostate Cancer Cases in the UK: Evidence for a More Extensive Genetic Panel

(2019) Daniel A. Leongamornlert et al.   EUROPEAN UROLOGY

Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

(2019) Mev Dominguez-Valentin et al.   GENETICS IN MEDICINE

Prostate Cancer Risks for Male BRCA1 and BRCA2 Mutation Carriers: A Prospective Cohort Study

(2019) Tommy Nyberg et al.   EUROPEAN UROLOGY

Interim Results from the IMPACT Study: Evidence for Prostate-specific Antigen Screening in BRCA2 Mutation Carriers

(2019) Elizabeth C. Page et al.   EUROPEAN UROLOGY

Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness

(2019) Vivek L. Patel et al.   CANCER RESEARCH

Polygenic risk-tailored screening for prostate cancer: A benefit–harm and cost-effectiveness modelling study

(2019) Tom Callender et al.   PLOS MEDICINE

Rare germline variants in DNA repair genes and the angiogenesis pathway predispose prostate cancer patients to develop metastatic disease

(2018) Martina Mijuskovic et al.   BRITISH JOURNAL OF CANCER

Role of Genetic Testing for Inherited Prostate Cancer Risk: Philadelphia Prostate Cancer Consensus Conference 2017

(2018) Veda N. Giri et al.   JOURNAL OF CLINICAL ONCOLOGY

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

(2018) Fredrick R. Schumacher et al.   NATURE GENETICS

A comprehensive evaluation of CHEK2 germline mutations in men with prostate cancer

(2018) Yishuo Wu et al.   PROSTATE

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants

(2018) Tokhir Dadaev et al.   Nature Communications

Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies

(2018) Lisa Pennells et al.   EUROPEAN HEART JOURNAL

Homeobox B13 G84E Mutation and Prostate Cancer Risk

(2018) Tommy Nyberg et al.   EUROPEAN UROLOGY

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

Germline variation at 8q24 and prostate cancer risk in men of European ancestry

(2018) Marco Matejcic et al.   Nature Communications

Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores

(2017) Julie Lecarpentier et al.   JOURNAL OF CLINICAL ONCOLOGY

Screening Men at Increased Risk for Prostate Cancer Diagnosis: Model Estimates of Benefits and Harms

(2016) Roman Gulati et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers

(2016) Christopher I. Amos et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Familial Risk and Heritability of Cancer Among Twins in Nordic Countries

(2016) Lorelei A. Mucci et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer

(2016) Colin C. Pritchard et al.   NEW ENGLAND JOURNAL OF MEDICINE

Adding genetic risk score to family history identifies twice as many high-risk men for prostate cancer: Results from the prostate cancer prevention trial

(2016) Haitao Chen et al.   PROSTATE

Prevalence of the HOXB13 G84E germline mutation in British men and correlation with prostate cancer risk, tumour characteristics and clinical outcomes

(2015) Z. Kote-Jarai et al.   ANNALS OF ONCOLOGY

Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility Loci

(2015) A. Amin Al Olama et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Implications of polygenic risk-stratified screening for prostate cancer on overdiagnosis

(2015) Nora Pashayan et al.   GENETICS IN MEDICINE

Gene-Panel Sequencing and the Prediction of Breast-Cancer Risk

(2015) Douglas F. Easton et al.   NEW ENGLAND JOURNAL OF MEDICINE

Prediction of individual genetic risk to prostate cancer using a polygenic score

(2015) Robert Szulkin et al.   PROSTATE

Active monitoring, radical prostatectomy, or radiotherapy for localised prostate cancer: study design and diagnostic and baseline results of the ProtecT randomised phase 3 trial

(2014) J Athene Lane et al.   LANCET ONCOLOGY

Mendel: the Swiss army knife of genetic analysis programs

(2013) Kenneth Lange et al.   BIOINFORMATICS

HOXB13 G84E Mutation in Finland: Population-Based Analysis of Prostate, Breast, and Colorectal Cancer Risk

(2013) V. H. Laitinen et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Elevated Risk of Prostate Cancer Among Men With Lynch Syndrome

(2013) Victoria M. Raymond et al.   JOURNAL OF CLINICAL ONCOLOGY

Socioeconomic Variation and Prostate Specific Antigen Testing in the Community: A United Kingdom Based Population Study

(2013) Rhian M. Morgan et al.   JOURNAL OF UROLOGY

Common Genetic Variants in Prostate Cancer Risk Prediction--Results from the NCI Breast and Prostate Cancer Cohort Consortium (BPC3)

(2012) S. Lindstrom et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Concordance of Tumor Differentiation Among Brothers with Prostate Cancer

(2012) K. Fredrik Jansson et al.   EUROPEAN UROLOGY

A Population-based Assessment of Germline HOXB13 G84E Mutation and Prostate Cancer Risk

(2012) Robert Karlsson et al.   EUROPEAN UROLOGY

Risk Prediction of Complex Diseases from Family History and Known Susceptibility Loci, with Applications for Cancer Screening

(2011) Hon-Cheong So et al.   AMERICAN JOURNAL OF HUMAN GENETICS

An Epidemiological Reappraisal of the Familial Aggregation of Prostate Cancer: A Meta-Analysis

(2011) Michał Kiciński et al.   PLoS One

Age-Specific Risk of Incident Prostate Cancer and Risk of Death from Prostate Cancer Defined by the Number of Affected Family Members

(2010) Andreas Brandt et al.   EUROPEAN UROLOGY

Effects of Prostate-Specific Antigen Testing on Familial Prostate Cancer Risk Estimates

(2010) O. Bratt et al.   JNCI-Journal of the National Cancer Institute

Inherited genetic markers discovered to date are able to identify a significant number of men at considerably elevated risk for prostate cancer

(2010) Jielin Sun et al.   PROSTATE

Stage Shift in Psa-detected Prostate Cancers – Effect Modification by Gleason Score

(2009) Nora Pashayan et al.   JOURNAL OF MEDICAL SCREENING

Estimation of absolute risk for prostate cancer using genetic markers and family history

(2009) Jianfeng Xu et al.   PROSTATE

The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions

(2008) A C Antoniou et al.   BRITISH JOURNAL OF CANCER