P/CAF mediates PAX3-FOXO1-dependent oncogenesis in alveolar rhabdomyosarcoma

PCAF-primed EZH2 acetylation regulates its stability and promotes lung adenocarcinoma progression

(2015) Junhu Wan et al.   NUCLEIC ACIDS RESEARCH

KATs in cancer: functions and therapies

(2015) A Farria et al.   ONCOGENE

GLI inhibitor GANT-61 diminishes embryonal and alveolar rhabdomyosarcoma growth by inhibiting Shh/AKT-mTOR axis

(2015) Ritesh K. Srivastava et al.   Oncotarget

Lineage of origin in rhabdomyosarcoma informs pharmacological response

(2014) J. Abraham et al.   GENES & DEVELOPMENT

Probing p300/CBP Associated Factor (PCAF)-Dependent Pathways with a Small Molecule Inhibitor

(2013) Rahul Modak et al.   ACS Chemical Biology

Histone Acetyltransferase PCAF Is Required for Hedgehog-Gli-Dependent Transcription and Cancer Cell Proliferation

(2013) M. Malatesta et al.   CANCER RESEARCH

A call to ARMS: targeting thePAX3-FOXO1gene in alveolar rhabdomyosarcoma

(2013) Mary E Olanich et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Mechanisms of impaired differentiation in rhabdomyosarcoma

(2013) Charles Keller et al.   FEBS Journal

Small Molecule Inhibition of PAX3-FOXO1 through AKT Activation Suppresses Malignant Phenotypes of Alveolar Rhabdomyosarcoma

(2013) M. Jothi et al.   MOLECULAR CANCER THERAPEUTICS

Acetylation Stabilizes ATP-Citrate Lyase to Promote Lipid Biosynthesis and Tumor Growth

(2013) Ruiting Lin et al.   MOLECULAR CELL

Modulation of lysine methylation in myocyte enhancer factor 2 during skeletal muscle cell differentiation

(2013) Jinmi Choi et al.   NUCLEIC ACIDS RESEARCH

The Polycomb group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx)

(2013) R Ciarapica et al.   ONCOGENE

Carnitine palmitoyltransferase 1A (CPT1A): a transcriptional target of PAX3-FKHR and mediates PAX3-FKHR–dependent motility in alveolar rhabdomyosarcoma cells

(2012) Lingling Liu et al.   BMC CANCER

A Mouse Model of Rhabdomyosarcoma Originating from the Adipocyte Lineage

(2012) Mark E. Hatley et al.   CANCER CELL

The ablation of EZH2 uncovers its crucial role in rhabdomyosarcoma formation

(2012) Irene Marchesi et al.   CELL CYCLE

Alveolar rhabdomyosarcoma-associated proteins PAX3/FOXO1A and PAX7/FOXO1A suppress the transcriptional activity of MyoD-target genes in muscle stem cells

(2012) F Calhabeu et al.   ONCOGENE

Lysine methyltransferase G9a methylates the transcription factor MyoD and regulates skeletal muscle differentiation

(2012) B. M. T. Ling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alveolar rhabdomyosarcoma – The molecular drivers of PAX3/7-FOXO1-induced tumorigenesis

(2012) Amy D Marshall et al.   Skeletal Muscle

Embelin suppresses STAT3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase PTEN

(2011) Ji Young Heo et al.   CANCER LETTERS

Histone Methyltransferase KMT1A Restrains Entry of Alveolar Rhabdomyosarcoma Cells into a Myogenic Differentiated State

(2011) M.-H. Lee et al.   CANCER RESEARCH

Genome-Wide Identification of PAX3-FKHR Binding Sites in Rhabdomyosarcoma Reveals Candidate Target Genes Important for Development and Cancer

(2010) L. Cao et al.   CANCER RESEARCH

Regulating a master regulator

(2010) Arif Aziz et al.   Epigenetics

Embelin Suppresses Osteoclastogenesis Induced by Receptor Activator of NF-κB Ligand and Tumor CellsIn vitrothrough Inhibition of the NF-κB Cell Signaling Pathway

(2010) Simone Reuter et al.   MOLECULAR CANCER RESEARCH

PCAF represses transactivation function of FOXO1 in an acetyltransferase-independent manner

(2009) Kenji Yoshimochi et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

PAX3–FOXO1 fusion gene in rhabdomyosarcoma

(2008) Corinne M. Linardic   CANCER LETTERS

Phosphorylation Regulates Transcriptional Activity of PAX3/FKHR and Reveals Novel Therapeutic Possibilities

(2008) R. Amstutz et al.   CANCER RESEARCH

Identification of PAX3-FKHR-regulated genes differentially expressed between alveolar and embryonal rhabdomyosarcoma: Focus onMYCN as a biologically relevant target

(2008) Gabriela E. Mercado et al.   GENES CHROMOSOMES & CANCER

PCAF Acetylates β-Catenin and Improves Its Stability

(2008) Xinjian Ge et al.   MOLECULAR BIOLOGY OF THE CELL

Effects of PAX3-FKHR on malignant phenotypes in alveolar rhabdomyosarcoma

(2007) Ken Kikuchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS