Optimizing warfarin dosing using deep reinforcement learning

Applications of machine learning in decision analysis for dose management for dofetilide

(2020) Andrew E. Levy et al.   PLoS One

Trends in anticoagulant prescribing: a review of local policies in English primary care

(2020) Katherine H. Ho et al.   BMC HEALTH SERVICES RESEARCH

Outcome-Driven Personalized Treatment Design for Managing Diabetes

(2018) Eva K. Lee et al.   INTERFACES

Reinforcement learning-based control of drug dosing for cancer chemotherapy treatment

(2017) Regina Padmanabhan et al.   MATHEMATICAL BIOSCIENCES

Personalized AnticoagulationCLINICAL PERSPECTIVE

(2017) Kourosh Ravvaz et al.   Circulation-Cardiovascular Genetics

Human-level control through deep reinforcement learning

(2015) Volodymyr Mnih et al.   NATURE

Clinical Practice Recommendations on Genetic Testing of CYP2C9 and VKORC1 Variants in Warfarin Therapy

(2015) Kaitlyn Shaw et al.   THERAPEUTIC DRUG MONITORING

A Randomized Trial of Genotype-Guided Dosing of Warfarin

(2013) Munir Pirmohamed et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Systems Approach to Designing Effective Clinical Trials Using Simulations

(2012) Vincent A. Fusaro et al.   CIRCULATION

A Proposal for an Individualized Pharmacogenetics-Based Warfarin Initiation Dose Regimen for Patients Commencing Anticoagulation Therapy

(2011) P J Avery et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Integration of Genetic, Clinical, and INR Data to Refine Warfarin Dosing

(2010) P Lenzini et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

A Pharmacometric Model Describing the Relationship Between Warfarin Dose and INR Response With Respect to Variations in CYP2C9, VKORC1, and Age

(2010) A-K Hamberg et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Informing sequential clinical decision-making through reinforcement learning: an empirical study

(2010) Susan M. Shortreed et al.   MACHINE LEARNING

Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data

(2009)   NEW ENGLAND JOURNAL OF MEDICINE

Use of Pharmacogenetic and Clinical Factors to Predict the Therapeutic Dose of Warfarin

(2008) BF Gage et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS