Article
Medicine, General & Internal
Sebastiano Mercadante, Augusto Caraceni, Arturo Cuomo, Massimo Mammucari, Paolo Marchetti, Rocco Domenico Mediati, Silvia Natoli, Giuseppe Tonini
Summary: After one-month follow-up, cancer patients experienced a lower number of breakthrough pain episodes and peak intensity, potentially due to optimization of background analgesia. The principal characteristics of breakthrough pain did not change significantly, highlighting the importance of careful and continuous assessment for patients to alleviate the burden induced by breakthrough pain episodes.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Oncology
Marco Cascella, Anna Crispo, Gennaro Esposito, Cira Antonietta Forte, Sergio Coluccia, Giuseppe Porciello, Alfonso Amore, Sabrina Bimonte, Sebastiano Mercadante, Augusto Caraceni, Massimo Mammucari, Paolo Marchetti, Rocco Domenico Mediati, Silvia Natoli, Giuseppe Tonini, Arturo Cuomo
Summary: This paper addresses the management of NP-BTcP through a mathematical approach, offering important clinical insights and providing guidance for identifying diagnostic and therapeutic gaps.
Article
Pharmacology & Pharmacy
Sebastiano Mercadante, Russell K. Portenoy
Summary: Breakthrough cancer pain (BTcP) is a complex phenomenon that varies between individuals and may change over time. Personalized management requires appropriate assessment of BTcP patterns. The use of opioids, specifically fentanyl products with rapid onset and offset, is recommended. The optimal opioid dose remains a controversial topic, with conflicting recommendations regarding dosing strategies.
Article
Nursing
Siqing Chen, Meijuan Cao, Jing Zhang, Lili Yang, Xiaolin Xu, Xingwei Zhang
Summary: This study developed a health literacy assessment instrument for patients with chronic pain using the Delphi technique. The instrument consists of three dimensions and 41 items. The evaluation results of two rounds of Delphi showed that the instrument is valid and suitable for investigating the health literacy level of patients with chronic pain.
Article
Health Care Sciences & Services
Morena Shkodra, Cinzia Brunelli, Ernesto Zecca, Gabriele Infante, Rosalba Miceli, Mariangela Caputo, Paola Bracchi, Silvia Lo Dico, Stein Kaasa, Augusto Caraceni
Summary: This study aimed to identify prognostic factors associated with cancer pain intensity in order to guide improvements in cancer pain classification. The findings suggest that breakthrough/episodic pain and the diagnosis of pain syndrome are significantly associated with higher pain intensity during follow-up.
PALLIATIVE MEDICINE
(2022)
Article
Oncology
Marco Mazzotta, Marco Filetti, Marta Piras, Sebastiano Mercadante, Paolo Marchetti, Raffaele Giusti
Summary: This study aims to identify factors that can predict patients' satisfaction with pain relief for breakthrough cancer pain (BTcP). The results showed that younger age, non metastatic cancer stage, high Karnofsky performance status, absence of anticancer treatment, and high BTcP interference in activities of daily living were positively correlated with dissatisfaction.
CANCER MANAGEMENT AND RESEARCH
(2022)
Article
Rehabilitation
Adrienne R. Harvey, Clare T. McKinnon, Nadine Smith, Katarina Ostojic, Simon P. Paget, Suzanne Smith, Daisy A. Shepherd, Jenny Lewis, Angie Morrow
Summary: This study conducted a modified electronic Delphi study to establish consensus on essential domains for measuring chronic pain in children and young people with cerebral palsy. After two rounds of surveys, 12 core domains were identified, which will be utilized to build a specific framework for pain assessment in this population.
DISABILITY AND REHABILITATION
(2022)
Article
Medicine, General & Internal
G. M. Massen, R. J. Allen, O. C. Leavy, N. M. Selby, G. P. Aithal, N. Oliver, H. Parfrey, L. Wain, G. Jenkins, I Stewart, J. K. Quint
Summary: Traditionally, clinical research has focused on individual fibrotic diseases or fibrosis in a particular organ. However, it is possible for people to have multiple fibrotic diseases. This study used a Delphi method to reach consensus on which diseases may be described as fibrotic.
QJM-AN INTERNATIONAL JOURNAL OF MEDICINE
(2023)
Article
Oncology
Albert Tuca Rodriguez, Miguel Nunez Viejo, Pablo Maradey, Jaume Canal-Sotelo, Placido Guardia Mancilla, Sonia Gutierrez Rivero, Inmaculada Raja Casillas, Maria Herrera Abian, Cristina Lopez Bermudo
Summary: Individualized management of breakthrough cancer pain (BTcP) can improve quality of life (QoL) for patients with advanced cancer, with transmucosal fentanyl at low doses being the most common drug used.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Pharmacology & Pharmacy
Han Xie, Xinyi Chen, Min Xue, Huaying Li, Yonghan Ge, Weihong Ge
Summary: This study aimed to construct a pharmaceutical care mode for cancer pain patients in primary care and analyze its effect on drug therapy treatment. The results showed that under the scientific and reasonable mode of pharmaceutical care, the pain assessment rate and reasonable rate of pain assessment were significantly higher, while the pain score and incidence of adverse reactions were significantly lower.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Health Care Sciences & Services
Karlotta Schloesser, Yvonne Eisenmann, Anja Bergmann, Steffen T. Simon
Summary: Through a Delphi survey, experts on breathlessness agreed on 15 cognitive and behavioral strategies to develop a personalized intervention for managing episodic breathlessness. The final intervention includes strategies such as handheld fan, forward lean, diaphragmatic breathing, distraction, pursed lips breathing, long breaths out, and relaxation training.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2021)
Article
Environmental Sciences
Francisco Villegas, Veronica Martinez-Borba, Carlos Suso-Ribera, Diana Castilla, Irene Zaragoza, Azucena Garcia-Palacios, Carlos Ferrer
Summary: Using mobile applications for ecological momentary assessment of cancer pain is feasible and acceptable, reducing recall bias and enabling quicker response to adverse events. Clinical alarms prove useful in timely detection and addressing of abnormalities.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Neurosciences
Catherine Stratton, Areti Vassilopoulos, J. Nicholas Brenton, Kirsten Potter, Wendy Vargas, Heather Rumm, Andrea Bartels, Mary Bailey, Charles Odonkor, Sharon Stoll, E. William T. Zempsky, E. Ann Yeh, Naila Makhani
Summary: This study aimed to develop an interdisciplinary interim guideline for the assessment and management of pain in children with MS. Literature on pain in children with MS is scarce, and further studies are needed to assess the implementation of these guidelines in clinical settings.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Medicine, General & Internal
David De la Rosa, Paz Sanz-Ayan, Antonio Alcantara, Cesar Margarit, Juana Sanchez, Miguel Sanfeliu, Ana Aleo
Summary: The study aimed to establish a consensus on assessment of function in chronic pain primary care patients and evaluate the use of scales and clinical guidelines in clinical practice. Results showed that physicians agreed on the need for a precise definition of patient functional impediment and the development of simple and practical scales.
CURRENT MEDICAL RESEARCH AND OPINION
(2021)
Article
Orthopedics
Vikas Khanduja, Nicholas Darby, John O'Donnell, Nicolas Bonin, Marc R. Safran
Summary: This study presents the first known expert consensus on diagnosing hip microinstability. The complex nature of the final diagnostic tool highlights the challenges clinicians face in making this diagnosis.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2023)
Article
Oncology
Sara Alfieri, Cinzia Brunelli, Giuseppe Capri, Augusto Caraceni, Giulia V. Bianchi, Claudia Borreani
Summary: The study aims to understand the needs of patients with metastatic breast cancer, and identified four themes through thematic analysis: the need for clinical recognition, more attention from healthcare professionals, more and better services available at the hospital, and specific public health policies. The findings suggest that changes in attitudes and multidisciplinary practices are needed to meet these needs in the metastatic phase of breast cancer.
JOURNAL OF CANCER EDUCATION
(2022)
Review
Health Care Sciences & Services
Henry Davies, Mohammed A. Waduud, Ryan Laloo, Lucy Wyld, Tom Wallace, Jonathan R. de Siqueira, Michael I. Bennett, D. Julian A. Scott
Summary: Despite the high mortality and morbidity associated with Peripheral Artery Disease (PAD), evidence of the effectiveness of palliative care in this group of patients is lacking. There are only a handful of articles on palliative care for people with PAD, and the majority are small, methodologically flawed and lack meaningful patient-reported outcomes. High-quality research of palliative care interventions in patients with PAD is urgently needed to better understand the impact of palliative care on quality of end of life and to develop and evaluate service-level interventions.
JOURNAL OF PALLIATIVE MEDICINE
(2022)
Review
Health Care Sciences & Services
Emma J. Chapman, Erica Di Martino, Zoe Edwards, Kathryn Black, Matthew Maddocks, Michael Bennett
Summary: The study found that physical exercise interventions and energy conservation tactics are effective, while limited data are available on other interventions. Regular assessment of the impact of fatigue and emphasis on exercise and energy conservation are recommended. Pharmacological interventions are not supported as a routine approach, and further research on the efficacy of interventions recommended by guidelines is needed.
PALLIATIVE MEDICINE
(2022)
Article
Health Care Sciences & Services
Emma J. Chapman, Simon Pini, Zoe Edwards, Yousuf Elmokhallalati, Fliss E. M. Murtagh, Michael I. Bennett
Summary: Effective symptom management in specialist palliative care requires a coordinated, multi-faceted, sequential approach involving engagement, partnership, decision-making, and delivery. Barriers include team discordance and lack of understanding about symptom management. Shared decision-making and coordination by a multi-disciplinary team are key components of effective symptom management.
BMC PALLIATIVE CARE
(2022)
Editorial Material
Health Care Sciences & Services
Matthew John Allsop, Karen Chumbley, Jacqueline Birtwistle, Michael Bennett, Lucy Pocock
Summary: Digital technologies support advance care planning and care coordination in palliative and end of life care, but evidence is limited. The Electronic Palliative Care Coordination Systems (EPaCCS) in England are an ongoing development, and research is needed to determine their usefulness for patients with chronic and progressive illnesses.
BMJ SUPPORTIVE & PALLIATIVE CARE
(2022)
Article
Oncology
Salim M. Makhlouf, Shenaz Ahmed, Matthew Mulvey, Michael Bennett
Summary: This survey evaluated the knowledge, attitudes, and potential barriers of nurses and physicians in Libya regarding cancer pain management (CPM). The results showed that nurses had higher attitudinal barriers to CPM compared to physicians, and participants with higher educational levels had lower barrier scores. The survey suggests the need for professional education and training to address barriers and improve knowledge and attitudes towards CPM in Libya.
JOURNAL OF CANCER EDUCATION
(2023)
Editorial Material
Health Care Sciences & Services
Gemma Clarke, Jumilla Akhtar Hussain, Matthew John Allsop, Michael Bennett
Summary: Complete and valid ethnicity data are crucial for monitoring racial and ethnic disparities, and palliative care could potentially lead in this area.
BMJ SUPPORTIVE & PALLIATIVE CARE
(2022)
Article
Oncology
S. Pini, H. L. Bekker, M. Bennett, L. Ziegler
Summary: The aim of this study was to test an intervention to facilitate timely conversations about palliative care between patients and clinicians. The STEP intervention generated important early conversations about end-of-life care that may otherwise not have occurred.
Article
Nursing
Natasha Campling, Jacqueline Birtwistle, Alison Richardson, I. Michael Bennett, David Meads, Miriam Santer, Sue Latter
Summary: This study evaluates patient and carer access to medicines at the end of life and includes case studies of different service delivery models. The findings highlight the complexity of accessing medicines and the importance of coordination between patients, carers, and healthcare professionals.
INTERNATIONAL JOURNAL OF NURSING STUDIES
(2022)
Article
Gastroenterology & Hepatology
Roberta Jordan, Yousuf ElMokhallalati, Lynsey Corless, Michael Bennett
Summary: Patients with liver disease face difficulties in accessing end-of-life care, with a higher percentage of them dying in hospitals and receiving less specialized palliative care compared to those with malignant liver disease. Caregivers of patients with non-malignant liver disease were less likely to rate the quality of end-of-life care as outstanding/excellent.
LIVER INTERNATIONAL
(2023)
Article
Health Care Sciences & Services
Andrew J. Page, Katie Spencer, Matthew R. Mulvey, Barry J. A. Laird, Michael Bennett
Summary: This study analyzed a database from a regional radiotherapy center and found that using NSAIDs as adjuncts for cancer-induced bone pain is feasible, with 65.3% of patients dying within one year of radiotherapy.
PALLIATIVE MEDICINE
(2022)
Article
Primary Health Care
Yousuf ElMokhallalati, Emma Chapman, Samuel Relton, Michael Bennett, Lucy Ziegler
Summary: Recently, there has been a focus on providing good-quality end-of-life care for patients living at home. This study used data from a national survey in England to determine the characteristics of good-quality end-of-life care for home-based patients. The results showed that patients who had good continuity of primary care and palliative care support experienced better overall quality of end-of-life care. Patients with cancer and those who died outside of hospital were more likely to receive good end-of-life care. Older age, being female, living in areas with lower socioeconomic deprivation, and being White were associated with better overall end-of-life care.
BRITISH JOURNAL OF GENERAL PRACTICE
(2023)
Letter
Health Care Sciences & Services
Karen Neoh, Andrew Page, Nicolas Chin-Yee, Carolyn Doree, Michael Bennett
PALLIATIVE MEDICINE
(2023)
Article
Primary Health Care
Yousuf ElMokhallalati, Emma Chapman, Samuel D. Relton, Michael I. Bennett, Lucy Ziegler
Summary: Receiving good continuity of primary care and palliative care support, as well as dying outside of hospital, are characteristics of good-quality end-of-life care for patients living at home. Being older, female, from areas with less socioeconomic deprivation, and being White are associated with better overall end-of-life care. However, disparities still exist for patients from minority ethnic groups and living in areas of socioeconomic deprivation.
BRITISH JOURNAL OF GENERAL PRACTICE
(2023)
Review
Medicine, General & Internal
Mia Schmidt-Hansen, Michael Bennett, Stephanie Arnold, Nathan Bromham, Jennifer S. Hilgart, Andrew J. Page, Yuan Chi
Summary: The study assessed the effectiveness and tolerability of oxycodone compared to other analgesic options for cancer pain relief in adults, finding little to no difference between oxycodone and other strong opioids including morphine in terms of pain intensity, pain relief, and adverse events.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2022)