The RNA-binding protein CSTF2 regulates BAD to inhibit apoptosis in glioblastoma

Hallmarks of Cancer: New Dimensions

(2022) Douglas Hanahan   Cancer Discovery

Cleavage stimulation factor 2 promotes malignant progression of liver hepatocellular carcinoma by activating phosphatidylinositol 3′-kinase/protein kinase B/mammalian target of rapamycin pathway

(2022) Meng-Hui Zhang et al.   Bioengineered

RNA‐binding protein ELAVL2 plays post‐transcriptional roles in the regulation of spermatogonia proliferation and apoptosis

(2021) Chao Yang et al.   CELL PROLIFERATION

RNA ‐binding protein RBM38 inhibits colorectal cancer progression by partly and competitively binding to PTEN 3′ UTR with miR ‐92a‐3p

(2021) Bugao Guan et al.   ENVIRONMENTAL TOXICOLOGY

The 2021 WHO Classification of Tumors of the Central Nervous System: a summary

(2021) David N Louis et al.   NEURO-ONCOLOGY

CstF64-Induced Shortening of the BID 3′UTR Promotes Esophageal Squamous Cell Carcinoma Progression by Disrupting ceRNA Cross-talk with ZFP36L2

(2021) Ai Lin et al.   CANCER RESEARCH

CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2014–2018

(2021) Quinn T Ostrom et al.   NEURO-ONCOLOGY

Management of glioblastoma: State of the art and future directions

(2020) Aaron C. Tan et al.   CA-A CANCER JOURNAL FOR CLINICIANS

RND2 attenuates apoptosis and autophagy in glioblastoma cells by targeting the p38 MAPK signalling pathway

(2020) Yang Xu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The mTOR regulated RNA-binding protein LARP1 requires PABPC1 for guided mRNA interaction

(2020) Ewan M Smith et al.   NUCLEIC ACIDS RESEARCH

Clinical practice guidelines for the management of adult diffuse gliomas

(2020) Tao Jiang et al.   CANCER LETTERS

Tissue-specific mechanisms of alternative polyadenylation: Testis, brain, and beyond (2018 update)

(2019) Clinton C. MacDonald   Wiley Interdisciplinary Reviews-RNA

TIPE3 is a regulator of cell apoptosis in glioblastoma

(2019) Fanen Yuan et al.   CANCER LETTERS

Bad phosphorylation as a target of inhibition in oncology

(2018) Ngoc-Linh-Chi Bui et al.   CANCER LETTERS

CSTF2-induced shortening of the RAC1 3'UTR promotes the pathogenesis of urothelial carcinoma of the bladder

(2018) Xin Chen et al.   CANCER RESEARCH

What Are 3′ UTRs Doing?

(2018) Christine Mayr   Cold Spring Harbor Perspectives in Biology

GlioVis data portal for visualization and analysis of brain tumor expression datasets

(2016) Robert L. Bowman et al.   NEURO-ONCOLOGY

Glioblastoma: pathology, molecular mechanisms and markers

(2015) Kenneth Aldape et al.   ACTA NEUROPATHOLOGICA

CstF-64 and 3′-UTRcis-element determine Star-PAP specificity for target mRNA selection by excluding PAPα

(2015) Divya T. Kandala et al.   NUCLEIC ACIDS RESEARCH

Targeting proapoptotic protein BAD inhibits survival and self-renewal of cancer stem cells

(2014) K S R Sastry et al.   CELL DEATH AND DIFFERENTIATION

CFIm25 links alternative polyadenylation to glioblastoma tumour suppression

(2014) Chioniso P. Masamha et al.   NATURE

Dynamic analyses of alternative polyadenylation from RNA-seq reveal a 3′-UTR landscape across seven tumour types

(2014) Zheng Xia et al.   Nature Communications

Deregulated Signaling Pathways in Glioblastoma Multiforme: Molecular Mechanisms and Therapeutic Targets

(2012) Hua Mao et al.   CANCER INVESTIGATION

Mechanistic Insights into the Antileukemic Activity of Hyperforin

(2012) C. Billard et al.   CURRENT CANCER DRUG TARGETS

Transcriptome-wide analyses of CstF64-RNA interactions in global regulation of mRNA alternative polyadenylation

(2012) C. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

JC-1: alternative excitation wavelengths facilitate mitochondrial membrane potential cytometry

(2012) A Perelman et al.   Cell Death & Disease

Glioblastoma: From Molecular Pathology to Targeted Treatment

(2011) Timothy F. Cloughesy et al.   Annual Review of Pathology-Mechanisms of Disease

Targeting apoptosis pathways in glioblastoma

(2011) Günter Eisele et al.   CANCER LETTERS

Characterization of a Cleavage Stimulation Factor, 3′ pre-RNA, Subunit 2, 64 kDa (CSTF2) as a Therapeutic Target for Lung Cancer

(2011) Masato Aragaki et al.   CLINICAL CANCER RESEARCH

Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics

(2010) Camilla Krakstad et al.   Molecular Cancer

Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

(2009) Christine Mayr et al.   CELL

The Hinge Domain of the Cleavage Stimulation Factor Protein CstF-64 Is Essential for CstF-77 Interaction, Nuclear Localization, and Polyadenylation

(2009) J. Andrew Hockert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BAD: undertaker by night, candyman by day

(2009) N N Danial   ONCOGENE