Toll‐like receptor‐2 in cardiomyocytes and macrophages mediates isoproterenol‐induced cardiac inflammation and remodeling

Toll-like receptor 2 signaling deficiency in cardiac cells ameliorates Ang II-induced cardiac inflammation and remodeling

(2021) Shiju Ye et al.   Translational Research

Quantitative Proteomics Reveal That Metabolic Improvement Contributes to the Cardioprotective Effect of T89 on Isoproterenol-Induced Cardiac Injury

(2021) Xiao-Hong Wei et al.   Frontiers in Physiology

Innate Immune Cells in Pressure Overload-Induced Cardiac Hypertrophy and Remodeling

(2021) Xin Liu et al.   Frontiers in Cell and Developmental Biology

Macrophage-derived myeloid differentiation protein 2 plays an essential role in ox-LDL-induced inflammation and atherosclerosis

(2020) Taiwei Chen et al.   EBioMedicine

Resveratrol prevents ISO-induced myocardial remodeling associated with regulating polarization of macrophages through VEGF-B/AMPK/NF-kB pathway

(2020) Yafei Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Cells of the adult human heart

(2020) Monika Litviňuková et al.   NATURE

Transmembrane tumor necrosis factor alpha attenuates pressure-overload cardiac hypertrophy via tumor necrosis factor receptor 2

(2020) Kun Miao et al.   PLOS BIOLOGY

HuR regulates phospholamban expression in isoproterenol-induced cardiac remodelling

(2019) Han Hu et al.   CARDIOVASCULAR RESEARCH

Targeting Extracellular Heat Shock Protein 70 Ameliorates Doxorubicin‐Induced Heart Failure Through Resolution of Toll‐Like Receptor 2–Mediated Myocardial Inflammation

(2019) Peng Liu et al.   Journal of the American Heart Association

Systemic inflammation and functional capacity in elderly heart failure patients

(2018) Sara Radenovic et al.   Clinical Research in Cardiology

Targeting HMGB1 ameliorates cardiac fibrosis through restoring TLR2-mediated autophagy suppression in myocardial fibroblasts

(2018) Ri-Na Wu et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Toll-like receptor 2 deficiency hyperactivates the FoxO1 transcription factor and induces aging-associated cardiac dysfunction in mice

(2018) Kondapalli Mrudula Spurthi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toll-like receptor expression and apoptosis morphological patterns in female rat hearts with takotsubo syndrome induced by isoprenaline

(2018) Agnieszka Kołodzińska et al.   LIFE SCIENCES

The Role of Toll-Like Receptor Signaling in the Progression of Heart Failure

(2018) Lili Yu et al.   MEDIATORS OF INFLAMMATION

Fibronectin (FN) cooperated with TLR2/TLR4 receptor to promote innate immune responses of macrophages via binding to integrin β1

(2018) Dongsheng Fei et al.   Virulence

Saturated palmitic acid induces myocardial inflammatory injuries through direct binding to TLR4 accessory protein MD2

(2017) Yi Wang et al.   Nature Communications

Toll-Like Receptor 4 Inhibition Improves Oxidative Stress and Mitochondrial Health in Isoproterenol-Induced Cardiac Hypertrophy in Rats

(2017) Parmeshwar B. Katare et al.   Frontiers in Immunology

Leukocytic Toll-Like Receptor 2 Deficiency Preserves Cardiac Function And Reduces Fibrosis In Sustained Pressure Overload

(2017) Jiong-Wei Wang et al.   Scientific Reports

NF-κB inhibition attenuates LPS-induced TLR4 activation in monocyte cells

(2016) Jian Wan et al.   Molecular Medicine Reports

Mechanotransduction in Cardiac Hypertrophy and Failure

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Restoring Anticancer Immune Response by Targeting Tumor-Derived Exosomes With a HSP70 Peptide Aptamer

(2015) Jessica Gobbo et al.   JNCI-Journal of the National Cancer Institute

Restoring Anticancer Immune Response by Targeting Tumor-Derived Exosomes With a HSP70 Peptide Aptamer

(2015) Jessica Gobbo et al.   JNCI-Journal of the National Cancer Institute

Toll-like receptor 2/4 heterodimer mediates inflammatory injury in intracerebral hemorrhage

(2014) Yan-Chun Wang et al.   ANNALS OF NEUROLOGY

Toll-Like Receptor 4 Knockout Protects Against Isoproterenol-Induced Cardiac Fibrosis

(2014) Rui-qing Dong et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Inhibition of Toll-like receptor 2 reduces cardiac fibrosis by attenuating macrophage-mediated inflammation

(2013) Lei Wang et al.   CARDIOVASCULAR RESEARCH

CpG-ODN Attenuates Pathological Cardiac Hypertrophy and Heart Failure by Activation of PI3Kα-Akt Signaling

(2013) Liang Yang et al.   PLoS One

Unique mechanistic insights into the beneficial effects of soluble epoxide hydrolase inhibitors in the prevention of cardiac fibrosis

(2013) P. Sirish et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toll‐Like Receptor‐2 Mediates Adaptive Cardiac Hypertrophy in Response to Pressure Overload Through Interleukin‐1β Upregulation via Nuclear Factor κB Activation

(2013) Yasutomi Higashikuni et al.   Journal of the American Heart Association

Inhibition of high glucose-induced inflammatory response and macrophage infiltration by a novel curcumin derivative prevents renal injury in diabetic rats

(2012) Yong Pan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Rodent models of heart failure: an updated review

(2012) A. C. Gomes et al.   HEART FAILURE REVIEWS

Multiple Facets of NF-κB in the Heart

(2011) Joseph W. Gordon et al.   CIRCULATION RESEARCH

Arteriogenesis requires toll-like receptor 2 and 4 expression in bone-marrow derived cells

(2010) Daphne de Groot et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Pressure-Mediated Hypertrophy and Mechanical Stretch Induces IL-1 Release and Subsequent IGF-1 Generation to Maintain Compensative Hypertrophy by Affecting Akt and JNK Pathways

(2009) Shoken Honsho et al.   CIRCULATION RESEARCH

TOLL-LIKE RECEPTORS IN ISCHEMIA-REPERFUSION INJURY

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Beneficial effects of bisoprolol on the survival of hypertensive diastolic heart failure model rats

(2008) Mayu Nishio et al.   EUROPEAN JOURNAL OF HEART FAILURE

A GRK5 polymorphism that inhibits β-adrenergic receptor signaling is protective in heart failure

(2008) Stephen B Liggett et al.   NATURE MEDICINE