Novel therapy of hyperhomocysteinemia in mild cognitive impairment, Alzheimer’s disease, and other dementing disorders

Hyperhomocysteinemia and Risk of Cognitive Decline: A Meta-Analysis of Prospective Cohort Studies

(2017) Tian Nie et al.   EUROPEAN NEUROLOGY

Lifetime requirement of the methionine cycle for neuronal development and maintenance

(2014) Thomas B. Shea et al.   CURRENT OPINION IN PSYCHIATRY

Impaired one carbon metabolism and DNA methylation in alcohol toxicity

(2014) Inna I. Kruman et al.   JOURNAL OF NEUROCHEMISTRY

24-Hour Rhythms of DNA Methylation and Their Relation with Rhythms of RNA Expression in the Human Dorsolateral Prefrontal Cortex

(2014) Andrew S. P. Lim et al.   PLoS Genetics

Plasma homocysteine, Alzheimer and cerebrovascular pathology: a population-based autopsy study

(2013) Babak Hooshmand et al.   BRAIN

Interactions between plasma concentrations of folate and markers of vitamin B12 status with cognitive performance in elderly people not exposed to folic acid fortification: the Hordaland Health Study

(2013) Esmée L. Doets et al.   BRITISH JOURNAL OF NUTRITION

Aberrant DNA methylation of miR-219 promoter in long-term night shiftworkers

(2013) Fengqin Shi et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

N-acetyl-cysteine prevents pyramidal cell disarray and reelin-immunoreactive neuron deficiency in CA3 after prenatal immune challenge in rats

(2013) Aline Rideau Batista Novais et al.   PEDIATRIC RESEARCH

Chronic homocysteine exposure causes changes in the intrinsic electrophysiological properties of cultured hippocampal neurons

(2013) Christina Schaub et al.   EXPERIMENTAL BRAIN RESEARCH

Risk Profiles for Mild Cognitive Impairment Vary by Age and Sex: The Sydney Memory and Ageing Study

(2012) Perminder S. Sachdev et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Conversion from mild cognitive impairment to dementia: Influence of folic acid and vitamin B12 use in the vita cohort

(2012) Imrich Blasko et al.   Journal of Nutrition Health & Aging

Homocysteine, Frailty, and All-Cause Mortality in Older Men: The Health in Men Study

(2012) Y. Y. E. Wong et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Rescue from a two hit, high-throughput model of neurodegeneration with N-acetyl cysteine

(2012) Ajay S. Unnithan et al.   NEUROCHEMISTRY INTERNATIONAL

Comparison of the Memory Performance Index With Standard Neuropsychological Measures of Cognition

(2011) Michael Rafii et al.   American Journal of Alzheimers Disease and Other Dementias

Vitamin B-12 and homocysteine status in a folate-replete population: results from the Canadian Health Measures Survey

(2011) Amanda J MacFarlane et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

A randomized placebo controlled trial of homocysteine lowering to reduce cognitive decline in older demented people

(2011) T. Kwok et al.   CLINICAL NUTRITION

Cognitive and clinical outcomes of homocysteine-lowering B-vitamin treatment in mild cognitive impairment: a randomized controlled trial

(2011) Celeste A. Jager et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Epigenetic regulation in obesity

(2011) C Lavebratt et al.   INTERNATIONAL JOURNAL OF OBESITY

N-acetyl Cysteine Treatment Rescues Cognitive Deficits Induced by Mitochondrial Dysfunction in G72/G30 Transgenic Mice

(2011) David-Marian Otte et al.   NEUROPSYCHOPHARMACOLOGY

Proteomic analysis of brain proteins in APP/PS-1 human double mutant knock-in mice with increasing amyloid β-peptide deposition: Insights into the effects of in vivo treatment with N-acetylcysteine as a potential therapeutic intervention in mild cognitive

(2011) Renã A. S. Robinson et al.   PROTEOMICS

Epigenetic priming of the metabolic syndrome

(2011) Kimberley D Bruce et al.   TOXICOLOGY MECHANISMS AND METHODS

Epigenetics and cardiovascular disease

(2010) José M. Ordovás et al.   Nature Reviews Cardiology

Development and validation of the Memory Performance Index: Reducing measurement error in recall tests

(2009) William R. Shankle et al.   Alzheimers & Dementia

Metabolic evidence of vitamin B-12 deficiency, including high homocysteine and methylmalonic acid and low holotranscobalamin, is more pronounced in older adults with elevated plasma folate

(2009) Joshua W Miller et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Homocysteine and Cognitive Impairment

(2008) Isabel Sala et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Homocysteine inhibits proliferation of neuronal precursors in the mouse adult brain by impairing the basic fibroblast growth factor signaling cascade and reducing extracellular regulated kinase 1/2-dependent cyclin E expression

(2008) Luis G. Rabaneda et al.   FASEB JOURNAL

B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteine, depletes brain S-adenosylmethionine, and enhances PS1 and BACE expression and amyloid-β deposition in mice

(2008) Andrea Fuso et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Homocysteine, Folate and Cognition in a Large Community-Based Sample of Elderly People – The 3C Dijon Study

(2008) Jean-Sébastien Vidal et al.   NEUROEPIDEMIOLOGY

A pilot study for circadian gene disturbance in dementia patients

(2008) Hsing-Cheng Liu et al.   NEUROSCIENCE LETTERS