Novel Therapeutic Strategies to Reduce Reperfusion Injury After Acute Myocardial Infarction

Hypothermia for Cardioprotection in Patients with St-Elevation Myocardial Infarction: Do Not Give It the Cold Shoulder Yet!

(2022) Mohamed El Farissi et al.   Journal of Clinical Medicine

Percutaneous Transvalvular Microaxial Flow Pump Support in Cardiology

(2022) Enzo Lüsebrink et al.   CIRCULATION

Heart failure-related quality-of-life impairment after myocardial infarction

(2022) Peter Wohlfahrt et al.   Clinical Research in Cardiology

Heart Failure After ST-Elevation Myocardial Infarction: Beyond Left Ventricular Adverse Remodeling

(2022) Marco Giuseppe Del Buono et al.   CURRENT PROBLEMS IN CARDIOLOGY

Left ventricular remodelling post-myocardial infarction: pathophysiology, imaging, and novel therapies

(2022) Stefan Frantz et al.   EUROPEAN HEART JOURNAL

Intracoronary Application of Super-Saturated Oxygen to Reduce Infarct Size Following Myocardial Infarction

(2022) Andreas Schäfer et al.   Journal of Clinical Medicine

Pressure-controlled intermittent coronary sinus occlusion: A novel approach to improve microvascular flow and reduce infarct size in STEMI

(2022) C. Michael Gibson et al.   Cardiovascular Revascularization Medicine

C-Reactive Protein Triggers Cell Death in Ischemic Cells

(2021) Ahmed Sheriff et al.   Frontiers in Immunology

C-Reactive Protein Apheresis as Anti-inflammatory Therapy in Acute Myocardial Infarction: Results of the CAMI-1 Study

(2021) Wolfgang Ries et al.   Frontiers in Cardiovascular Medicine

Selective intracoronary hypothermia in patients with ST-elevation myocardial infarction. Rationale and design of the EURO-ICE trial

(2021) Mohamed El Farissi et al.   EuroIntervention

Pressure‐controlled intermittent coronary sinus occlusion improves the vasodilatory microvascular capacity and reduces myocardial injury in patients with STEMI

(2021) Roberto Scarsini et al.   CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS

Safety of Selective Intracoronary Hypothermia During Primary Percutaneous Coronary Intervention in Patients With Anterior STEMI

(2021) Mohamed El Farissi et al.   JACC-Cardiovascular Interventions

A multicentre, prospective, randomised controlled trial to assess the safety and effectiveness of cooling as an adjunctive therapy to percutaneous intervention in patients with acute myocardial infarction: the COOL AMI EU Pivotal Trial

(2021) Marko Noc et al.   EuroIntervention

Therapeutic Hypothermia Following Cardiac Arrest After the TTM2 trial – More Questions Raised Than Answered

(2021) Andreas Schäfer et al.   CURRENT PROBLEMS IN CARDIOLOGY

Update on Cardioprotective Strategies for STEMI

(2021) Robert A. Kloner et al.   JACC-Basic to Translational Science

Event-Free Survival Following Successful Percutaneous Intervention in Acute Myocardial Infarction Depends on Microvascular Perfusion

(2020) Feng Xie et al.   Circulation-Cardiovascular Imaging

Myocardial ischaemia–reperfusion injury and cardioprotection in perspective

(2020) Gerd Heusch   Nature Reviews Cardiology

Influence of Timing and Predicted Risk on Mortality in Impella-Treated Infarct-Related Cardiogenic Shock Patients

(2020) Andreas Schäfer et al.   Frontiers in Cardiovascular Medicine

Heart failure after myocardial infarction: incidence and predictors

(2020) Dominik Jenča et al.   ESC Heart Failure

Unloading the Left Ventricle Before Reperfusion in Patients With Anterior ST-Segment–Elevation Myocardial Infarction

(2019) Navin K. Kapur et al.   CIRCULATION

Clinical scenarios for use of transvalvular microaxial pumps in acute heart failure and cardiogenic shock – A European experienced users working group opinion

(2019) Andreas Schäfer et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm

(2019) Jean-Baptiste Lascarrou et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of Impella on Coronary Perfusion in Patients With Critical Coronary Artery Stenosis

(2018) Mohammad Alqarqaz et al.   Circulation-Cardiovascular Interventions

Left Ventricular Mechanical Unloading by Total Support of Impella in Myocardial Infarction Reduces Infarct Size, Preserves Left Ventricular Function, and Prevents Subsequent Heart Failure in Dogs

(2018) Keita Saku et al.   Circulation-Heart Failure

Indication and short-term clinical outcomes of high-risk percutaneous coronary intervention with microaxial Impella® pump: results from the German Impella® registry

(2018) Stefan Baumann et al.   Clinical Research in Cardiology

Impact of treatment delay on mortality in ST-segment elevation myocardial infarction (STEMI) patients presenting with and without haemodynamic instability: results from the German prospective, multicentre FITT-STEMI trial

(2018) Karl Heinrich Scholz et al.   EUROPEAN HEART JOURNAL

Evaluation of intracoronary hyperoxemic oxygen therapy in acute anterior myocardial infarction: The IC-HOT study

(2018) Shukri W. David et al.   CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS

Mortality in Patients With Out-of-Hospital Cardiac Arrest Undergoing a Standardized Protocol Including Therapeutic Hypothermia and Routine Coronary Angiography

(2018) Muharrem Akin et al.   JACC-Cardiovascular Interventions

Left Ventricular Unloading Before Reperfusion Promotes Functional Recovery After Acute Myocardial Infarction

(2018) Michele L. Esposito et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome

(2018) Gregory G. Schwartz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Relationship between microvascular obstruction and adverse events following primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: an individual patient data pooled analysis from seven randomized trials

(2017) Suzanne de Waha et al.   EUROPEAN HEART JOURNAL

Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease

(2017) Marc S. Sabatine et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rivaroxaban with or without Aspirin in Stable Cardiovascular Disease

(2017) John W. Eikelboom et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease

(2017)   NEW ENGLAND JOURNAL OF MEDICINE

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

(2017) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy of prasugrel administration immediately after percutaneous coronary intervention in ST-elevation myocardial infarction

(2017) Ulrike Flierl et al.   THROMBOSIS AND HAEMOSTASIS

Cardioprotection: Where to from here?

(2016) Robert A. Kloner et al.   CARDIOVASCULAR DRUGS AND THERAPY

Relationship Between Infarct Size and Outcomes Following Primary PCI

(2016) Gregg W. Stone et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Total Mechanical Unloading Minimizes Metabolic Demand of Left Ventricle and Dramatically Reduces Infarct Size in Myocardial Infarction

(2016) Keita Saku et al.   PLoS One

EMBRACE STEMI study: a Phase 2a trial to evaluate the safety, tolerability, and efficacy of intravenous MTP-131 on reperfusion injury in patients undergoing primary percutaneous coronary intervention

(2015) C. Michael Gibson et al.   EUROPEAN HEART JOURNAL

Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction

(2015) Marc P. Bonaca et al.   NEW ENGLAND JOURNAL OF MEDICINE

Selective apheresis of C-reactive protein: A new therapeutic option in myocardial infarction?

(2014) Ahmed Sheriff et al.   JOURNAL OF CLINICAL APHERESIS

Rationale and design of the EMBRACE STEMI Study: A phase 2a, randomized, double-blind, placebo-controlled trial to evaluate the safety, tolerability and efficacy of intravenous Bendavia on reperfusion injury in patients treated with standard therapy including primary percutaneous coronary intervention and stenting for ST-segment elevation myocardial infarction

(2013) Anjan K. Chakrabarti et al.   AMERICAN HEART JOURNAL

Myocardial ischemia-reperfusion injury: a neglected therapeutic target

(2013) Derek J. Hausenloy et al.   JOURNAL OF CLINICAL INVESTIGATION

The Current Use of Impella 2.5 in Acute Myocardial Infarction Complicated by Cardiogenic Shock: Results from the USpella Registry

(2013) WILLIAM W. O'NEILL et al.   JOURNAL OF INTERVENTIONAL CARDIOLOGY

A pooled analysis of the effect of endovascular cooling on infarct size in patients with ST-elevation myocardial infarction

(2013) David Erlinge et al.   EuroIntervention

A Prospective, Randomized Clinical Trial of Hemodynamic Support With Impella 2.5 Versus Intra-Aortic Balloon Pump in Patients Undergoing High-Risk Percutaneous Coronary Intervention

(2012) William W. O'Neill et al.   CIRCULATION

Vorapaxar in the Secondary Prevention of Atherothrombotic Events

(2012) David A. Morrow et al.   NEW ENGLAND JOURNAL OF MEDICINE

Reduction of Ischemia/Reperfusion Injury With Bendavia, a Mitochondria‐Targeting Cytoprotective Peptide

(2012) Robert A. Kloner et al.   Journal of the American Heart Association

The mitochondrial permeability transition pore and ischemia-reperfusion injury

(2009) Christopher P. Baines   BASIC RESEARCH IN CARDIOLOGY

Effect of Supersaturated Oxygen Delivery on Infarct Size After Percutaneous Coronary Intervention in Acute Myocardial Infarction

(2009) Gregg W. Stone et al.   Circulation-Cardiovascular Interventions

Time to Take Myocardial Reperfusion Injury Seriously

(2008) Derek J. Hausenloy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effect of Cyclosporine on Reperfusion Injury in Acute Myocardial Infarction

(2008) Christophe Piot et al.   NEW ENGLAND JOURNAL OF MEDICINE