Review
Oncology
Pierpaolo Biondetti, Lorenzo Saggiante, Anna Maria Ierardi, Massimo Iavarone, Angelo Sangiovanni, Filippo Pesapane, Enrico Maria Fumarola, Pietro Lampertico, Gianpaolo Carrafiello
Summary: Interventional radiology image-guided locoregional therapies for HCC have immunomodulatory effects, with a current interest in combining these therapies with immunotherapy for potential synergistic benefits. Immune activation by locoregional therapies alone may not be sufficient for a systemic antitumor response, leading to interest in combined treatments to improve outcomes.
Review
Medicine, General & Internal
Abdulaziz M. Al-Sharydah, Faisal Khalid BinShaiq, Rayan Ibrahim Aloraifi, Abdulrahman Abdulaziz Almefleh, Saud Abdulaziz Alessa, Adi Saud Alobud, Abdulmonem Mohammed AlSharidah, Abdulmajeed Bin Dahmash, Mohammad S. Al-Aftan, Bander Fuhaid Al-Dhaferi
Summary: Interventional radiology is a fast-paced specialty that utilizes advanced technological solutions. Despite the availability of procedural software, resources and real-world evidence related to such software are limited. This study reviews the current resources and highlights the lack of studies on procedural product software, indicating a need for further research and classification.
Review
Radiology, Nuclear Medicine & Medical Imaging
Kristy K. Brock, Stephen R. Chen, Rahul A. Sheth, Jeffrey H. Siewerdsen
Summary: Interventional radiology has evolved into a distinct clinical discipline with its own training pathway since the early 20th century. It utilizes a variety of imaging technologies, such as x-ray, CT, and MRI, to perform high-precision interventions.
Article
Oncology
Florian Nima Fleckenstein, Maximilian Julius Roesel, Maja Krajewska, Timo Alexander Auer, Federico Collettini, Tazio Maleitzke, Georg Boening, Giovanni Federico Torsello, Uli Fehrenbach, Bernhard Gebauer
Summary: This study analyzed the efficacy and safety of combining transarterial radioembolization (TARE) and CT-guided high-dose-rate interstitial brachytherapy (CT-HDRBT) for the treatment of primary and secondary liver tumors. The results showed that this treatment approach was effective and safe, and early application of TARE may have a positive impact on survival.
Review
Oncology
Hang Li, Li Chen, Guang-Yu Zhu, Xijuan Yao, Rui Dong, Jin-He Guo
Summary: Cholangiocarcinoma is the second most common type of primary liver malignancy, with surgical resection being the preferred treatment for eligible patients. Interventional treatment has become an acceptable palliative option for unresectable CCA, providing locoregional control, symptom relief, and improved quality of life.
FRONTIERS IN ONCOLOGY
(2021)
Review
Oncology
Anne E. Gill, C. Matthew Hawkins
Summary: Interventional radiology is a valuable resource for pediatric solid tumor patients, offering minimally invasive procedures for diagnosis and treatment. Advanced imaging techniques enhance visualization during biopsy procedures, locoregional treatments provide targeted therapy with limited side effects, and thermal ablation can treat chemo-resistant tumors. Interventional radiologists also perform routine procedures and provide support for oncology patients with high success rates and safety profiles.
PEDIATRIC BLOOD & CANCER
(2023)
Review
Medicine, General & Internal
Ferruccio Sgalambro, Luigi Zugaro, Federico Bruno, Pierpaolo Palumbo, Nicola Salducca, Carmine Zoccali, Antonio Barile, Carlo Masciocchi, Francesco Arrigoni
Summary: Interventional radiology (IR) has experienced significant growth and is widely used in the field of musculoskeletal. The main techniques used in IR include ablation, embolization, and cementoplasty. These techniques are used to treat bone metastases by destroying pathological tissue, blocking arterial vessels, and strengthening weakened bone segments.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Fiona Mankertz, Ole Gemeinhardt, Ute Felbor, Stefan Hadlich, Norbert Hosten
Summary: Thermal ablation is a minimally invasive treatment for hepatic tumors, but limited ablation size is a challenge due to the formation of a non-conductive boundary layer. We conducted a study using bovine liver to compare the ablation size created by a stand-alone laser applicator and a laser applicator with a spacer. The presence of a spacer significantly increased ablation volume up to 75.3 cm(3), with the closed spacer producing a significantly larger ablation volume and diameter compared to the open spacer. We conclude that using a spacer has the potential to increase ablation size.
Article
Radiology, Nuclear Medicine & Medical Imaging
D. Pencharz, T. Wagner
Summary: This study investigated the opinions of clinician referrers on the presence and type of management advice in reports of PET-CT examinations. The results showed that opinions varied among clinicians, but some themes predominated: (1) advice on further imaging tests and areas outside the referrer's expertise were more welcome; (2) a differential diagnosis or clinical significance was considered more valuable than specific management advice; (3) some referrers did not want any further advice. Therefore, reporters should consider clinicians' opinions before providing management advice, and seeking the opinions of clinicians in other hospitals may be necessary. A review of the Royal College of Radiologists Actionable Reports standard to align it with clinicians' opinions could be useful.
CLINICAL RADIOLOGY
(2023)
Article
Oncology
Stephen Hunt, Alireza Zandifar, Abass Alavi
Summary: Interventional oncologists use molecular imaging methods in the management of mCRC, including initial staging and pretreatment planning, predicting molecular subtypes and prognosis, intraoperative guidance, and evaluating treatment response and post-procedural monitoring.
INTERNATIONAL JOURNAL OF HYPERTHERMIA
(2022)
Review
Oncology
Sinan Akay, Janet H. Pollard, Assim Saad Eddin, Aiah Alatoum, Sedat Kandemirli, Ali Gholamrezanezhad, Yusuf Menda, Michael M. Graham, Ahmad Shariftabrizi
Summary: Sinonasal cancers are rare and often diagnosed late, making them difficult to treat. Whole-body F-18-FDG PET/CT is a useful tool in detecting and staging these cancers, while other imaging tracers like C-11-choline and Ga-68-DOTATATE/DOTATOC are helpful in treatment planning and monitoring progress. This review discusses the role of PET/CT in diagnosing, determining disease extent, treatment planning, and evaluating treatment response for different types of sinonasal tumors, as well as the use of newer radiotracers for PET scanning.
Article
Chemistry, Multidisciplinary
Dedai Lu, Mingshu Chen, Lili Yu, Zhengpeng Chen, Hongyun Guo, Yongdong Zhang, Zhiming Han, Tingting Xu, Haijun Wang, Xing Zhou, Zubang Zhou, Gaojun Teng
Summary: The PFP-m-Fe3O4@PGTTC-6.3 nanocomposite demonstrated specific tumor accumulation and embolization effects, inhibiting tumor growth and causing tumors to disappear within weeks after injection. The combination of embolization and magnetic hyperthermia therapy showed promising results in animal experiments, highlighting the potential of this system for solid tumor theranostics.
Review
Biology
Ernesto Punzi, Claudio Carrubba, Andrea Contegiacomo, Alessandro Posa, Pierluigi Barbieri, Davide De Leoni, Giulia Mazza, Alessandro Tanzilli, Alessandro Cina, Luigi Natale, Evis Sala, Roberto Iezzi
Summary: Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease, and only a minority of patients (2-3%) have a resectable disease at diagnosis. Interventional radiology is increasingly important in the treatment of surgically unresectable disease. This narrative review analyzes the safety and efficacy of ablative techniques in the management of borderline resectable and locally advanced diseases and highlights the role of interventional radiologists in managing patients with distant metastases. It also focuses on the synergy between immunotherapy and ablative therapies.
Article
Endocrinology & Metabolism
Ashley Kieran Clift, Robert Thomas, Andrea Frilling
Summary: Neuroendocrine liver metastases are commonly treated with liver-directed interventional therapies that exploit the blood supply characteristics to deliver therapy. Ongoing comparative trials are exploring different techniques and the combination of interventional therapies with systemic treatment in multimodal therapy concepts.
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Francesco Arrigoni, Giampaolo Bianchi, Francesco Formiconi, Pierpaolo Palumbo, Luigi Zugaro, Giovanni Luca Gravina, Antonio Barile, Carlo Masciocchi
Summary: Cryoablation is an advanced thermal ablation technique for managing bone metastases, which has shown effectiveness in pain relief and local disease control. Results of cryoablation procedures in the radiology department over the past seven years confirmed pain palliation and disease control, with minimal complications.
Article
Urology & Nephrology
Clement Michiels, Zine-Eddine Khene, Thomas Prudhomme, Astrid Boulenger de Hauteclocque, Francois H. Cornelis, Melanie Percot, Helene Simeon, Laure Dupitout, Henri Bensadoun, Gregoire Capon, Eric Alezra, Vincent Estrade, Franck Bladou, Gregoire Robert, Jean-Marie Ferriere, Nicolas Grenier, Nicolas Doumerc, Karim Bensalah, Jean-Christophe Bernhard
Summary: In robot-assisted partial nephrectomy (RAPN), using three-dimensional model reconstructions for preoperative planning and intraoperative guidance can reduce complications and improve perioperative clinical outcomes.
WORLD JOURNAL OF UROLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Eslam Youssef, Ernesto Santos, Amgad M. Moussa, Eric Lis, Maksim Vaynrub, Ori Barzilai, Mark Bilsky, Francois H. Cornelis
Summary: The purpose of this study was to evaluate the safety and effectiveness of preoperative embolization with nBCA in limiting blood loss during surgery for MSCC. The results showed that preoperative embolization with nBCA can effectively reduce tumor vascularity and is a safe procedure with acceptable blood loss and operative time.
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Leo Razakamanantsoa, Neeraj R. Rajagopalan, Yasushi Kimura, Michele Sabbah, Isabelle Thomassin-Naggara, Francois H. Cornelis, Govindarajan Srimathveeravalli
Summary: Irreversible electroporation (IRE) can cause apoptosis, necrosis, oncosis, or pyroptosis. The mode of cell death following IRE is determined by intracellular ATP levels. Cell death after IRE is insensitive to caspase inhibition and is correlated with ATP loss, which cannot be rescued by ATP supplementation.
BIOELECTROCHEMISTRY
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Vlasios Sotirchos, Constantinos T. Sofocleous
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Mahdi Zirakchian Zadeh, Randy Yeh, Assen S. Kirov, Henry S. Kunin, Mithat Gonen, Vlasios S. Sotirchos, Kevin S. Soares, Constantinos T. Sofocleous
Summary: This study aimed to evaluate the optimal segmentation method for colorectal liver metastasis (CLM) on immediate pre-ablation PET scans and assess the prognostic value of pre-ablation PET parameters in terms of local tumor control. The study also aimed to correlate the size estimation of target tumors by PET methods with tumor measurements on anatomical imaging.
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Amgad M. Moussa, Ahmed K. Aly, Majid Maybody, Juan C. Camacho, Fourat Ridouani, Adrian J. Gonzalez-Aguirre, Ernesto Santos
Summary: This study compared the safety and efficacy of sclerotherapy and lymphatic embolization (LE) in the treatment of symptomatic iatrogenic lymphoceles following percutaneous drain placement. The study found that LE had a higher clinical success rate after the first procedure and a shorter time to drain removal compared with sclerotherapy. There was no difference in the rate of adverse events between both groups. Further prospective studies are needed to compare the efficacy of both treatment modalities.
DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY
(2023)
Letter
Radiology, Nuclear Medicine & Medical Imaging
Omar Dzaye, Joseph P. Erinjeri, T. Peter Kingham, Francois H. Cornelis
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Milan Najdawi, Leo Razakamanantsoa, Cyril Mousseaux, Sofiane Bendifallah, Cyril Touboul, Isabelle Thomassin-Naggara, Marc Bazot, Matthias Barral, Francois H. Cornelis
Summary: This study retrospectively evaluated the relief of pain after percutaneous image-guided cryoablation of symptomatic extraperitoneal endometriosis. The results showed that cryoablation was effective in reducing pain and avoiding secondary surgery. The study concluded that percutaneous cryoablation is a safe and effective treatment for pain relief and local control of endometriosis.
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Review
Obstetrics & Gynecology
J. L. Brun, G. Plu-Bureau, C. Huchon, X. Ah-Kit, M. Barral, P. Chauvet, F. Cornelis, M. Cortet, P. Crochet, V. Delporte, G. Dubernard, G. Giraudet, A. Gosset, O. Graesslin, J. Hugon-Rodin, L. Lecointre, G. Legendre, L. Maitrot-Mantelet, L. Marcellin, L. Miquel, M. Le Mitouard, C. Proust, A. Roquette, P. Rousset, E. Sangnier, M. Sapoval, T. Thubert, A. Torre, F. Tremollieres, H. Vernhet-Kovacsik, F. Vidal, H. Marret
Summary: This study aims to provide French guidelines for the management of abnormal uterine bleeding (AUB). A committee of 26 experts developed recommendations independently of any industry funding, using the GRADE system to evaluate evidence quality. A total of 36 recommendations were formulated.
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
(2023)
Letter
Radiology, Nuclear Medicine & Medical Imaging
Jeffrey Sung, Britney Scott, Evan Matros, Jonas A. Nelson, Marc A. Cohen, Francois H. Cornelis
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Agnieszka Witkowska, Elena N. Petre, Amgad M. Moussa, Ernesto Santos, Debkumar Sarkar, Eric Lis, Francois H. Cornelis
Summary: This retrospective study evaluated the feasibility and safety of percutaneous CT-guided bone biopsies using a patient-mounted robotic system. The study found that this technique has a high technical success rate, adequate diagnostic yield, and favorable safety profile.
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Omar Dzaye, Akshaar Brahmbhatt, Aaron Abajian, Amgad M. Moussa, Kenny K. H. Yu, Nelson S. Moss, William C. Newman, Eric Lis, Viviane Tabar, Francois H. Cornelis
Summary: The purpose of this study was to evaluate the safety and efficacy of middle meningeal artery embolization performed under cone-beam computed tomography guidance in cancer patients. The results showed a 100% technical success rate and significant reduction in subdural hematoma size in the majority of cases.
DIAGNOSTIC AND INTERVENTIONAL IMAGING
(2023)
Review
Oncology
Samagra Jain, Harrison Blume, Lee Rodriguez, Elena Petre, Amgad Moussa, Ken Zhao, Vlasios Sotirchos, Nitya Raj, Diane Reidy, Etay Ziv, Erica Alexander
Summary: This study aimed to investigate the effectiveness and safety of hepatic hilar nerve blocks (HHNB) as analgesia for patients with neuroendocrine tumors (NET) treated with transarterial embolization (TAE). A retrospective study was conducted on NET patients who received TAE or TAE + HHNB between January 2020 and August 2022. The results showed that HHNB can be safely performed in NET patients, and there was no significant difference in the incidence of major complications or length of hospital stay between TAE and TAE + HHNB groups. However, HHNB recipients were more likely to use analgesic patches. Further study is needed to explore pain management after TAE.
Article
Radiology, Nuclear Medicine & Medical Imaging
Raphael Lehrer, Francois Cornelis, Jean-Christophe Bernhard, Pierre Bigot, Cecile Champy, Franck Bruyere, Morgan Roupret, Nicolas Doumerc, Charles-Karim Bensalah, Jonathan Olivier, Francois Audenet, Thibault Tricard, Bastien Parier, Xavier Durand, Matthieu Durand, Thomas Charles, Nicolas Branger, Louis Surlemont, Evanguelos Xylinas, Jean-Baptiste Beauval, Matthias Barral
Summary: This study compared the oncological and perioperative outcomes of robot-assisted partial nephrectomy (RPN) and percutaneous thermal ablation (PTA) for T1 renal cell cancer (RCC) in elderly patients. The results showed similar oncological outcomes between PTA and RPN in elderly patients.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ken Zhao, Joseph P. P. Erinjeri, Vlasios S. S. Sotirchos, Erica S. S. Alexander, Amgad M. M. Moussa, Brett Marinelli, Etay Ziv, Constantinos T. T. Sofocleous, Ghassan K. K. Abou-Alfa, William R. R. Jarnagin, Anita Karimi, Hooman Yarmohammadi
Summary: This study evaluated factors affecting the outcomes of transarterial radioembolization (TARE) in heavily pretreated intrahepatic cholangiocarcinoma (ICC) patients. The results showed that prior treatments, genomic status, and tumor size were associated with the efficacy of TARE. TARE may serve as a salvage therapy for heavily pretreated ICC patients.
ABDOMINAL RADIOLOGY
(2023)