Novel pathways of fluoride-induced hepatotoxicity: P53-dependent ferroptosis induced by the SIRT1/FOXOs pathway and Nrf2/HO-1 pathway

Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway

(2022) Ruozhi Dang et al.   Journal of Neuroinflammation

Sirtuin1 (SIRT1) is involved in the anticancer effect of black raspberry anthocyanins in colorectal cancer

(2022) Lili Chen et al.   EUROPEAN JOURNAL OF NUTRITION

PARP inhibition promotes ferroptosis via repressing SLC7A11 and synergizes with ferroptosis inducers in BRCA-proficient ovarian cancer

(2021) Ting Hong et al.   Redox Biology

ROS-Induced Hepatotoxicity under Cypermethrin: Involvement of the Crosstalk between Nrf2/Keap1 and NF-κB/iκB-α Pathways Regulated by Proteasome

(2021) Hongjing Zhao et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

The link between deacetylation and hepatotoxicity induced by exposure to hexavalent chromium

(2021) Qingyue Yang et al.   Journal of Advanced Research

Distribution of Fluoride in Plasma, Brain, and Bones and Associated Oxidative Damage After Induced Chronic Fluorosis in Wistar Rats

(2021) Priyanka Sharma et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Proteomics and transcriptomics jointly identify the key role of oxidative phosphorylation in fluoride-induced myocardial mitochondrial dysfunction in rats

(2021) Jiaxin Xie et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Recent advances in cellular effects of fluoride: an update on its signalling pathway and targeted therapeutic approaches

(2021) Apoorva H. Nagendra et al.   MOLECULAR BIOLOGY REPORTS

Exposure to Fluoride induces apoptosis in liver of ducks by regulating Cyt-C/Caspase 3/9 signaling pathway

(2021) Zhuanxu Ouyang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Cetuximab promotes RSL3-induced ferroptosis by suppressing the Nrf2/HO-1 signalling pathway in KRAS mutant colorectal cancer

(2021) Jiawen Yang et al.   Cell Death & Disease

Keratinocyte death by ferroptosis initiates skin inflammation after UVB exposure

(2021) Kavita Vats et al.   Redox Biology

Evaluation of Protective Effects of Curcumin and Nanocurcumin on Aluminium Phosphide‑Induced Subacute Lung Injury in Rats: Modulation of Oxidative Stress through SIRT1/FOXO3 Signalling Pathway

(2021) Mohammad Ali Mahlooji et al.   Drug Research

PACAP ameliorates fertility in obese male mice via PKA/CREB pathway‐dependent Sirt1 activation and p53 deacetylation

(2020) Qiuxia Yan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Chicken thalamic injury induced by copper (II) or / and arsenite exposure involves oxidative stress and inflammation-induced apoptosis

(2020) Dongxu Wang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Drp1/Mff signaling pathway is involved in fluoride-induced abnormal fission of hepatocyte mitochondria in mice

(2020) Bian-hua Zhou et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Iron and liver fibrosis: Mechanistic and clinical aspects

(2019) Kosha J Mehta et al.   WORLD JOURNAL OF GASTROENTEROLOGY

The pathogenesis of endemic fluorosis: Research progress in the last 5 years

(2019) Wei Wei et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway

(2019) Bo Chu et al.   NATURE CELL BIOLOGY

Resveratrol attenuates myocardial hypoxia/reoxygenation-induced cell apoptosis through DJ-1-mediated SIRT1-p53 pathway

(2019) Rui-Yuan Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Co-exposure to Arsenic-Fluoride Results in Endoplasmic Reticulum Stress-Induced Apoptosis Through the PERK Signaling Pathway in the Liver of Offspring Rats

(2019) Nisha Dong et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

p53 Suppresses Metabolic Stress-Induced Ferroptosis in Cancer Cells

(2018) Amy Tarangelo et al.   Cell Reports

Pre-and postnatal exposition to fluorides induce changes in rats liver morphology by impairment of antioxidant defense mechanisms and COX induction

(2018) K. Dec et al.   CHEMOSPHERE

Trehalose prevents cadmium-induced hepatotoxicity by blocking Nrf2 pathway, restoring autophagy and inhibiting apoptosis

(2018) Zhong-Gui Gong et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

High-fluoride promoted phagocytosis-induced apoptosis in a matured ameloblast-like cell line

(2015) Ting Yang et al.   ARCHIVES OF ORAL BIOLOGY

Dynamic roles of p53-mediated metabolic activities in ROS-induced stress responses

(2015) Le Jiang et al.   CELL CYCLE

Ferroptosis as a p53-mediated activity during tumour suppression

(2015) Le Jiang et al.   NATURE

Proteomic Analysis of Hippocampus in Offspring Male Mice Exposed to Fluoride and Lead

(2014) Ruiyan Niu et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Ameliorative effects of oleanolic acid on fluoride induced metabolic and oxidative dysfunctions in rat brain: Experimental and biochemical studies

(2014) Chaitali Sarkar et al.   FOOD AND CHEMICAL TOXICOLOGY

Effects of fluoride on liver apoptosis and Bcl-2, Bax protein expression in freshwater teleost, Cyprinus carpio

(2013) Jinling Cao et al.   CHEMOSPHERE

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Sirtuins as regulators of metabolism and healthspan

(2012) Riekelt H. Houtkooper et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Preclinical evaluation of a novel SIRT1 modulator SRT1720 in multiple myeloma cells

(2011) Dharminder Chauhan et al.   BRITISH JOURNAL OF HAEMATOLOGY