Design and methods of an open-label, randomized controlled trial to evaluate the effect of pemafibrate on proteinuria in CKD patients (PROFIT-CKD)

Relationship between serum lipid concentrations and impaired renal function in patients with chronic kidney disease: the Fukuoka Kidney Disease Registry Study

(2021) Toshiaki Nakano et al.   Clinical and Experimental Nephrology

Long-Term Efficacy and Safety of Pemafibrate, a Novel Selective Peroxisome Proliferator-Activated Receptor-α Modulator (SPPARMα), in Dyslipidemic Patients with Renal Impairment

(2019) Koutaro Yokote et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Lipids, Apolipoproteins, and Risk of Atherosclerotic Cardiovascular Disease in Persons With CKD

(2019) Archna Bajaj et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Lipotoxicity in Kidney, Heart, and Skeletal Muscle Dysfunction

(2019) Hiroshi Nishi et al.   Nutrients

Effects of Pemafibrate, a Novel Selective PPARα Modulator, on Lipid and Glucose Metabolism in Patients With Type 2 Diabetes and Hypertriglyceridemia: A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial

(2018) Eiichi Araki et al.   DIABETES CARE

Efficacy and Safety of Pemafibrate Versus Fenofibrate in Patients with High Triglyceride and Low HDL Cholesterol Levels: A Multicenter, Placebo-Controlled, Double-Blind, Randomized Trial

(2018) Hidenori Arai et al.   Journal of Atherosclerosis and Thrombosis

Effects of pemafibrate (K-877) on cholesterol efflux capacity and postprandial hyperlipidemia in patients with atherogenic dyslipidemia

(2018) Shizuya Yamashita et al.   Journal of Clinical Lipidology

Efficacy and safety of pemafibrate (K-877), a selective peroxisome proliferator-activated receptor α modulator, in patients with dyslipidemia: Results from a 24-week, randomized, double blind, active-controlled, phase 3 trial

(2018) Shun Ishibashi et al.   Journal of Clinical Lipidology

Effect of atorvastatin on iron metabolism regulation in patients with chronic kidney disease – a randomized double blind crossover study

(2018) Anna Masajtis-Zagajewska et al.   RENAL FAILURE

Renoprotective effect of a novel selective PPARα modulator K-877 in db/db mice: A role of diacylglycerol-protein kinase C-NAD(P)H oxidase pathway

(2017) Toshinobu Maki et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Renoprotective effects of atorvastatin compared with pravastatin on progression of early diabetic nephropathy

(2014) Akiko Takazakura et al.   Journal of Diabetes Investigation

Association Between Plasma Triglycerides and High-Density Lipoprotein Cholesterol and Microvascular Kidney Disease and Retinopathy in Type 2 Diabetes Mellitus

(2013) Frank M. Sacks et al.   CIRCULATION

Chronic Kidney Disease, Dyslipidemia, and Atherosclerosis

(2011) Tetsuo Shoji et al.   Journal of Atherosclerosis and Thrombosis

Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis

(2010)   LANCET

Effects of statins in patients with chronic kidney disease: meta-analysis and meta-regression of randomised controlled trials

(2008) Giovanni F M Strippoli et al.   BMJ-British Medical Journal