A decreasing CD4/CD8 ratio over time and lower CSF-penetrating antiretroviral regimens are associated with a higher risk of neurocognitive deterioration, independently of viral replication

Virologically suppressed patients with asymptomatic and symptomatic HIV-associated neurocognitive disorders do not display the same pattern of immune activation

(2015) M Vassallo et al.   HIV MEDICINE

Reliability and Clinical Relevance of the HIV-1 Drug Resistance Test in Patients With Low Viremia Levels

(2014) Maria Mercedes Santoro et al.   CLINICAL INFECTIOUS DISEASES

Neurocognitive Change in the Era of HIV Combination Antiretroviral Therapy: The Longitudinal CHARTER Study

(2014) R. K. Heaton et al.   CLINICAL INFECTIOUS DISEASES

Antiretroviral Treatment of Adult HIV Infection

(2014) Huldrych F. Günthard et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Increased Risk of Serious Non-AIDS-Related Events in HIV-Infected Subjects on Antiretroviral Therapy Associated with a Low CD4/CD8 Ratio

(2014) Sergio Serrano-Villar et al.   PLoS One

Clinical, Immunological and Treatment-Related Factors Associated with Normalised CD4+/CD8+ T-Cell Ratio: Effect of Naïve and Memory T-Cell Subsets

(2014) Willard Tinago et al.   PLoS One

Adjunctive and long-acting nanoformulated antiretroviral therapies for HIV-associated neurocognitive disorders

(2014) Howard E. Gendelman et al.   Current Opinion in HIV and AIDS

Association of HIV clinical disease progression with profiles of early immune activation

(2013) Roksana Karim et al.   AIDS

Can high central nervous system penetrating antiretroviral regimens protect against the onset of HIV-associated neurocognitive disorders?

(2013) Matteo Vassallo et al.   AIDS

Randomized Trial of Central Nervous System–Targeted Antiretrovirals for HIV-Associated Neurocognitive Disorder

(2013) Ronald J. Ellis et al.   CLINICAL INFECTIOUS DISEASES

The CD4:CD8 ratio is associated with markers of age-associated disease in virally suppressed HIV-infected patients with immunological recovery

(2013) S Serrano-Villar et al.   HIV MEDICINE

Relevance of lipopolysaccharide levels in HIV-associated neurocognitive impairment: the Neuradapt study

(2013) Matteo Vassallo et al.   JOURNAL OF NEUROVIROLOGY

Human T Cell Aging and the Impact of Persistent Viral Infections

(2013) T. Fülöp et al.   Frontiers in Immunology

Plasma HIV-1 RNA Levels During Antiretroviral Therapy: How Low Is Low Enough?

(2012) R. T. Gandhi et al.   CLINICAL INFECTIOUS DISEASES

Plasma HIV-1 RNA Detection Below 50 Copies/mL and Risk of Virologic Rebound in Patients Receiving Highly Active Antiretroviral Therapy

(2012) T. Doyle et al.   CLINICAL INFECTIOUS DISEASES

Defining Neurocognitive Impairment in HIV: Deficit Scores Versus Clinical Ratings

(2012) K. Blackstone et al.   CLINICAL NEUROPSYCHOLOGIST

The CD4/CD8 ratio in HIV-infected subjects is independently associated with T-cell activation despite long-term viral suppression

(2012) Sergio Serrano-Villar et al.   JOURNAL OF INFECTION

Role of obesity, metabolic variables, and diabetes in HIV-associated neurocognitive disorder

(2012) J. A. McCutchan et al.   NEUROLOGY

CD4 nadir is a predictor of HIV neurocognitive impairment in the era of combination antiretroviral therapy

(2011) Ronald J. Ellis et al.   AIDS

HIV-associated neurocognitive disorders: ‘mind the gap’

(2010) Justin C McArthur et al.   ANNALS OF NEUROLOGY

HIV Infection, Inflammation, Immunosenescence, and Aging

(2010) Steven G. Deeks   Annual Review of Medicine

HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors

(2010) Robert K. Heaton et al.   JOURNAL OF NEUROVIROLOGY

HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study

(2010) R. K. Heaton et al.   NEUROLOGY

Impact of combination antiretroviral therapy on cerebrospinal fluid HIV RNA and neurocognitive performance

(2009) Christina M Marra et al.   AIDS

Hodgkin lymphoma in the Swiss HIV Cohort Study

(2009) G. M. Clifford et al.   BLOOD

Dynamics of cognitive change in impaired HIV-positive patients initiating antiretroviral therapy

(2009) L. A. Cysique et al.   NEUROLOGY

Cognitive Neuropsychology of HIV-Associated Neurocognitive Disorders

(2009) Steven Paul Woods et al.   NEUROPSYCHOLOGY REVIEW

Validation of the CNS Penetration-Effectiveness Rank for Quantifying Antiretroviral Penetration Into the Central Nervous System

(2008) Scott Letendre   ARCHIVES OF NEUROLOGY