NEDD4 ameliorates myocardial reperfusion injury by preventing macrophages pyroptosis

Targeting CaMKII-δ9 Ameliorates Cardiac Ischemia/Reperfusion Injury by Inhibiting Myocardial Inflammation

(2022) Yuan Yao et al.   CIRCULATION RESEARCH

NLRP3 and pyroptosis blockers for treating inflammatory diseases

(2022) Rebecca C. Coll et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis

(2022) Chi G. Weindel et al.   CELL

Beclin-1 overexpression regulates NLRP3 activation by promoting TNFAIP3 in microvascular injury following myocardial reperfusion

(2021) Wenjing Sun et al.   CELLULAR SIGNALLING

Samotolisib Attenuates Acute Liver Injury Through Inhibiting Caspase-11-Mediated Pyroptosis Via Regulating E3 Ubiquitin Ligase Nedd4

(2021) Yang-Yang Zhao et al.   Frontiers in Pharmacology

Beclin1 controls caspase-4 inflammsome activation and pyroptosis in mouse myocardial reperfusion-induced microvascular injury

(2021) Wenjing Sun et al.   Cell Communication and Signaling

Distinct origins and functions of cardiac orthotopic macrophages

(2020) Zhen Wang et al.   BASIC RESEARCH IN CARDIOLOGY

Myocardial ischaemia–reperfusion injury and cardioprotection in perspective

(2020) Gerd Heusch   Nature Reviews Cardiology

Neuraminidase-1 promotes heart failure after ischemia/reperfusion injury by affecting cardiomyocytes and invading monocytes/macrophages

(2020) Maren Heimerl et al.   BASIC RESEARCH IN CARDIOLOGY

Evaluation of Microvascular Injury in Revascularized Patients with ST Elevation Myocardial Infarction Treated with Ticagrelor versus Prasugrel: The REDUCE-MVI Trial

(2019) Maarten A.H. van Leeuwen et al.   CIRCULATION

Multitarget Strategies to Reduce Myocardial Ischemia/Reperfusion Injury

(2019) Sean M. Davidson et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cardiac Hyaluronan Synthesis Is Critically Involved in the Cardiac Macrophage Response and Promotes Healing After Ischemia Reperfusion Injury

(2019) Anne Petz et al.   CIRCULATION RESEARCH

E3 ubiquitin ligase Nedd4 is a key negative regulator for non-canonical inflammasome activation

(2019) Qingjun Liu et al.   CELL DEATH AND DIFFERENTIATION

Gastrodin ameliorates microvascular reperfusion injury–induced pyroptosis by regulating the NLRP3/caspase-1 pathway

(2019) Wenjing Sun et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Cardiac monocytes and macrophages after myocardial infarction

(2019) Claire Peet et al.   CARDIOVASCULAR RESEARCH

HMGB1: LPS Delivery Vehicle for Caspase-11-Mediated Pyroptosis

(2018) Ho Min Kim et al.   IMMUNITY

The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation by promoting proteasomal degradation of NLRP3

(2016) Hui Song et al.   Nature Communications

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese

(2014) Megumi Hirokawa et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

NEDD4 ubiquitinates TRAF3 to promote CD40-mediated AKT activation

(2014) Di-Feng Fang et al.   Nature Communications

Monocyte and Macrophage Heterogeneity in the Heart

(2013) Matthias Nahrendorf et al.   CIRCULATION RESEARCH

Physiological functions of the HECT family of ubiquitin ligases

(2009) Daniela Rotin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells

(2008) Baoli Yang et al.   NATURE IMMUNOLOGY