Article
Endocrinology & Metabolism
Scheine Leite Canhada, Alvaro Vigo, Vivian Cristine Luft, Renata Bertazzi Levy, Sheila Maria Alvim Matos, Maria del Carmen Molina, Luana Giatti, Sandhi Barreto, Bruce Bartholow Duncan, Maria Ines Schmidt
Summary: The study aimed to investigate the association between consumption of ultra-processed food (UPF) and the incidence of metabolic syndrome (MetS). The results showed that for every increase of 150g/day in UPF consumption, there was a 7% higher risk of incident MetS. Compared to the first quartile, those in the fourth quartile had a 33% increased risk. These findings have important implications for diabetes and cardiovascular disease prevention and management.
Article
Clinical Neurology
Deepa Shokeen, Karen Sokal-Gutierrez
Summary: The study found a significant association between cardio-metabolic risk factors and clinically-significant depressive symptoms among US adults, with an increased number of CMR factors correlating with increased odds of CSD symptoms. The findings suggest the importance of comprehensive interventions addressing both mental health and physical health issues.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Review
Nutrition & Dietetics
Isabele Rejane de Oliveira Maranha, Mateus de Lima Macena, Eduardo Andre da Silva Junior, Dafiny Rodrigues Silva Praxedes, Lafs Gomes Lessa Vasconcelos, Nassib Bezerra Bueno
Summary: This meta-analysis aimed to evaluate the effect of early time-restricted feeding (eTRF) on the metabolic profile of adults with excess weight. The results showed potential benefits of eTRF on fasting blood glucose and HOMA-IR, although caution is needed due to the low-quality evidence.
CLINICAL NUTRITION
(2021)
Article
Endocrinology & Metabolism
Lili Liu, Wei Chen, Dan Wu, Fang Hu
Summary: This meta-analysis and systematic review suggests that time-restricted eating may be an effective approach to improving the metabolic state of nonobese individuals, particularly overweight individuals.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Endocrinology & Metabolism
Yanyan Dai, Yujuan Li, Shu Yang, Weiwei Xu, Hong Jia, Chao Yang
Summary: Weight change is associated with the risk of metabolic abnormalities. Long-term excessive weight gain is positively associated with an increased risk of metabolic abnormalities in non-overweight/obese individuals, while long-term weight loss is a protective factor for metabolic health in overweight/obese individuals.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Nutrition & Dietetics
Priscila dos Santos Gomes Olivares, Ana Beatriz Furlanetto Pacheco, Luciana Nicolau Aranha, Bianca da Silva Oliveira, Allan Amorim Santos, Paula Cristina Moreira dos Santos, Jose Firmino Nogueira Neto, Glorimar Rosa, Glaucia Maria Moraes Oliveira
Summary: This study investigated the gut microbiota of individuals with different metabolic phenotypes and found that metabolically healthy individuals had lower saturated fat intake and fasting glycemia. Those with unhealthy phenotypes had inflammation-associated microbiota, lower potential for butyrate production, and reduced bacterial diversity.
Article
Public, Environmental & Occupational Health
Chan Yang, Xiaowei Liu, Yuanyuan Dang, Juan Li, Jingyun Jing, Di Tian, Jiangwei Qiu, Jiaxing Zhang, Ni Yan, Xiuying Liu, Yi Zhao, Yuhong Zhang
Summary: The study found that in a population sample from northwest China, the incidence of type 2 diabetes mellitus (T2DM) was higher in the metabolically healthy overweight/obese (MHO) and metabolically unhealthy overweight/obese (MUO) groups. The co-occurrence of obesity and metabolic abnormalities increased the risk of developing T2DM.
INTERNATIONAL JOURNAL OF PUBLIC HEALTH
(2022)
Review
Cardiac & Cardiovascular Systems
Omid Eslami, Fatemeh Khorramrouz, Mohammadhassan Sohouli, Niloofar Bagheri, Farzad Shidfar, Maria Luz Fernandez
Summary: This systematic review and meta-analysis summarized the effects of incorporating nuts into the diet of healthy adults with overweight/obesity on serum lipid profile, glycemic markers, and blood pressure. The results showed that nut consumption can decrease serum triglycerides and LDL-cholesterol levels, but does not affect serum total cholesterol, high-density lipoprotein cholesterol, glycemic markers, and blood pressure.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2022)
Article
Public, Environmental & Occupational Health
Pravat Bhandari, Ezra Gayawan, Suryakant Yadav
Summary: The study examines the spatial patterns of underweight and overweight among adult men and women in different districts of India, finding that malnutrition burden shows geographical divides across the country. While overweight is prevalent in southern and northern India, underweight risks are higher in central, western, and eastern regions. Despite limited evidence on the double burden of malnutrition, sixty-six districts with double burden have been identified, highlighting the need for specialized policy initiatives to address the coexistence of underweight and overweight issues.
PUBLIC HEALTH NUTRITION
(2021)
Article
Medicine, Research & Experimental
Haoneng Tang, Ning Liu, Xiaojing Feng, Yanyi Yang, Yiyuan Fang, Siqi Zhuang, Yufeng Dai, Meilian Liu, Lingli Tang
Summary: This study revealed that circulating levels of IL-33 were significantly elevated in overweight/obese Chinese adults with metabolic disorders, and increased levels of IL-33 were positively associated with metabolically unhealthy overweight/obese phenotype and several metabolic syndrome risk factors.
JOURNAL OF TRANSLATIONAL MEDICINE
(2021)
Article
Medicine, General & Internal
Wenjing Zhao, Cheng Zhao
Summary: This study investigates the phenotypic transition characteristics of metabolic obesity in Chinese adults and its association with hyperuricemia. Results show that metabolic obesity phenotype is associated with an increased risk of hyperuricemia, regardless of body weight. The study emphasizes the importance of monitoring the transition of metabolic health status over time and implementing individualized prevention strategies for metabolically unhealthy and obese individuals.
Article
Environmental Sciences
Qianfeng Liu, Dan Wang, Wen Li, Xiaoyu Li, Ze Yang, Ai Zhang, Jiayu He, Xu Chen, Ying Chang, Xi Chen, Nai-jun Tang
Summary: Prenatal exposure to heavy metals poses multiple hazards to fetal growth and development. This study found a positive association between metal mixtures and the risk of fetal chromosomal abnormalities, with antimony (Sb) being the primary contributing factor. Furthermore, Sb levels were associated with Klinefelter syndrome and Turner syndrome, providing a genetic perspective on the effects of heavy metals on sexual development in humans.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Engineering, Environmental
Donghai Liang, Kaitlin Taibl, Anne Dunlop, Dana Boyd Barr, P. Barry Ryan, Todd Everson, Anke Huels, Youran Tan, Parinya Panuwet, Kurunthachalam Kannan, Carmen Marsit, Dean Jones, Stephanie Eick
Summary: Prenatal exposure to PFAS mixture affects the metabolome and is associated with systemic inflammation and oxidative stress. This study demonstrates the feasibility and utility of using metabolomics to assess the joint effects of multiple PFAS chemicals on human health.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Multidisciplinary Sciences
Jennifer L. Kuk, Simone B. Daniels, Chris I. Ardern, Rubin Pooni
Summary: There were differences in the types of weight loss strategies used by individuals over time, with variations in their popularity of use by sex and obesity status. Women and those with obesity were more likely to engage in weight loss practices, with diet-related weight loss being the most common and the use of weight loss drugs and products being the least common. The prevalence of exercise weight loss practices increased significantly among women with obesity.
Article
Medicine, General & Internal
Felix Teufel, Jacqueline A. Seiglie, Pascal Geldsetzer, Michaela Theilmann, Maja E. Marcus, Cara Ebert, William Andres Lopez Arboleda, Kokou Agoudavi, Glennis Andall-Brereton, Krishna K. Aryal, Brice Wilfried Bicaba, Garry Brian, Pascal Bovet, Maria Dorobantu, Mongal Singh Gurung, David Guwatudde, Corine Houehanou, Dismand Houinato, Jutta M. Adelin Jorgensen, Gibson B. Kagaruki, Khem B. Karki, Demetre Labadarios, Joao S. Martins, Mary T. Mayige, Roy Wong McClure, Joseph Kibachio Mwangi, Omar Mwalim, Bolormaa Norov, Sarah Crooks, Farshad Farzadfar, Sahar Saeedi Moghaddam, Bahendeka K. Silver, Lela Sturua, Chea Stanford Wesseh, Andrew C. Stokes, Utibe R. Essien, Jan-Walter De Neve, Rifat Atun, Justine I. Davies, Sebastian Vollmer, Till W. Barnighausen, Mohammed K. Ali, James B. Meigs, Deborah J. Wexler, Jennifer Manne-Goehler
Summary: The prevalence of overweight, obesity, and diabetes is increasing rapidly in low-income and middle-income countries, with BMI affecting the risk of diabetes, but there are significant regional variations in this association.
Article
Medicine, General & Internal
Maoxiang Zhao, Lulu Song, Qianqian Zhao, Yating Chen, Bin Li, Zhonghui Xie, Zihao Fu, Nan Zhang, Xiaowei Cheng, Xiaoqian Li, Miao Wang, Shouling Wu, Hao Xue, Yang Li
Summary: This study aimed to evaluate the impacts of obesity and variability of body mass index (BMI) and waist circumference (WC) on the risk of atrial fibrillation (AF). The results showed that elevated levels of BMI and WC were associated with an increased risk of AF, while variability in BMI and WC were not. Therefore, controlling BMI and WC levels may be beneficial for AF prevention.
Article
Cardiac & Cardiovascular Systems
Dankang Li, Lulin Wang, Ziyi Zhou, Lulu Song, Shuohua Chen, Yingping Yang, Yonghua Hu, Youjie Wang, Shouling Wu, Yaohua Tian
Summary: This study aimed to explore the role of socioeconomic, lifestyle, and clinical risk factors in the progression of cardiometabolic multimorbidity. The study found that socioeconomic and lifestyle factors were not only important predictors of multimorbidity in those with existing cardiometabolic disease, but also important in shaping risk of mortality.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2022)
Article
Respiratory System
Feipeng Cui, Yu Sun, Junqing Xie, Dankang Li, Mingyang Wu, Lulu Song, Yonghua Hu, Yaohua Tian
Summary: This study aimed to explore the association between air pollutants and the risk of idiopathic pulmonary fibrosis (IPF), as well as the modification effect of genetic susceptibility. The results showed that long-term exposure to air pollutants may increase the risk of incident IPF, with additive effects between air pollutants and genetic susceptibility.
EUROPEAN RESPIRATORY JOURNAL
(2023)
Article
Engineering, Environmental
Liqin Hu, Bin Zhou, Yaping Li, Lulu Song, Jin Wang, Meng Yu, Xiang Li, Ling Liu, Jing Kou, Youjie Wang, Xijiang Hu, Surong Mei
Summary: This study conducted in Liuzhou, China, involved 1156 children and adolescents aged 6-18 years. The findings suggest that exposure to organophosphate esters (OPEs) may have adverse effects on thyroid function, especially in children and adolescents. The study also found that OPE exposure was associated with increased levels of triiodothyronine (T3) and free triiodothyronine (FT3) in males, and decreased levels of free thyroxine (FT4) in females.
ENVIRONMENTAL GEOCHEMISTRY AND HEALTH
(2023)
Article
Environmental Sciences
Yunyun Liu, Lulu Song, Mingyang Wu, Jianing Bi, Lulin Wang, Qing Liu, Chao Xiong, Zhongqiang Cao, Shunqing Xu, Youjie Wang
Summary: This study investigates the association between prenatal rare earth elements (REE) exposure and newborn telomere length (TL), and finds a significant correlation between second trimester REE concentration and increased TL in newborns.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Nutrition & Dietetics
Dankang Li, Lulu Song, Lulin Wang, Shuohua Chen, Yingping Yang, Yonghua Hu, Youjie Wang, Shouling Wu, Yaohua Tian
Summary: This study used multiple measurements of fasting plasma glucose to identify different trajectories and their association with lifetime risk of cardiovascular disease. The study found that both a decrease in fasting plasma glucose over time and consistently lower levels were associated with lower lifetime risk of cardiovascular disease.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Infectious Diseases
Yi Guo, Hao Wang, Mingzhong Xiao, Xin Guan, Yanshou Lei, Tingyue Diao, Pinpin Long, Rui Zeng, Xuefeng Lai, Hao Cai, Yutong You, Yuying Wen, Wenhui Li, Xi Wang, Yufei Wang, Qinlin Chen, Yuchan Yang, Yutong Qiu, Jishuai Chen, Huidan Zeng, Wei Ni, Youyun Zhao, Kani Ouyang, Jingzhi Wang, Qi Wang, Li Liu, Lulu Song, Youjie Wang, Huan Guo, Xiaodong Li, Tangchun Wu, Yu Yuan
Summary: This study aimed to describe the long-term outcomes and ongoing pathophysiological alterations among COVID-19 survivors. A longitudinal cohort of 208 convalescents were followed up at different time points. Most convalescents showed improved physical and psychological health, but a small proportion still had sequelae symptoms, residual lung lesions, exercise impairment, and mental health disorders at 18.5 months.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Cardiac & Cardiovascular Systems
Yingping Yang, Lulu Song, Lulin Wang, Dankang Li, Shuohua Chen, Shouling Wu, Yaohua Tian
Summary: This study aimed to identify the trajectory of body mass index (BMI) and explore its association with cardiovascular disease (CVD) in the Chinese population. Long-term overweight and obesity were found to be associated with an increased lifetime risk of CVD. These findings are important for predicting the population burden of CVD.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2023)
Article
Oncology
Hao Wang, Yu Yuan, Bihao Wu, Mingzhong Xiao, Zhen Wang, Tingyue Diao, Rui Zeng, Li Chen, Yanshou Lei, Pinpin Long, Yi Guo, Xuefeng Lai, Yuying Wen, Wenhui Li, Hao Cai, Lulu Song, Wei Ni, Youyun Zhao, Kani Ouyang, Jingzhi Wang, Qi Wang, Li Liu, Chaolong Wang, An Pan, Xiaodong Li, Rui Gong, Tangchun Wu
Summary: A long-term study on 208 COVID-19 convalescents found that administration of two doses of inactivated vaccine enhanced neutralization against highly mutated SARS-CoV-2 variants and memory B cell responses. It is recommended to update vaccination guidelines and policies to include two doses of inactivated vaccine for COVID-19 convalescents in order to prevent further spread of the pandemic.
FRONTIERS OF MEDICINE
(2023)
Article
Environmental Sciences
Yaping Li, Liqin Hu, Bin Zhou, Zhiyi Zheng, Qitong Xu, Jun Liu, Lulu Song, Youjie Wang, Surong Mei
Summary: This study investigates the association between organophosphate esters (OPEs) and body mass index (BMI) z-score in children and adolescents, and explores the mediating role of sex hormones. The results show that certain OPE metabolites are negatively associated with BMI z-score, and sex hormones mediate this association. The findings suggest that OPEs may impair growth and development in children by disrupting sex hormone levels.
Article
Environmental Sciences
Zhengce Wan, Mingyang Wu, Qing Liu, Gaojie Fan, Qing Fang, Xiya Qin, Xukuan Zhang, Yongman Lv, Youjie Wang, Jianing Bi, Lulu Song
Summary: This study investigated the independent and joint associations of metal exposure with arterial stiffness. The results showed that the concentrations of copper and chromium were associated with an increased risk of arterial stiffness. These findings provide a target for preventative strategies against cardiovascular aging.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Environmental Sciences
Mingye Zhang, Limei Wang, Xiang Li, Lulu Song, Dan Luo, Qiang Li, Youjie Wang, Zhengce Wan, Surong Mei
Summary: This study investigated the association between individual and combined exposure to PCBs and OCPs and the risk of metabolic syndrome (MetS) in Wuhan, China. The results showed that PCBs and OCPs were commonly detected in the samples and were positively correlated with increased odds of MetS. Furthermore, the mixture of PCBs and OCPs, with p,p'-DDE being the largest contributor, was also associated with the risk of MetS.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Clinical Neurology
Qing Liu, Lulu Song, Gaojie Fan, Mingyang Wu, Jianing Bi, Luli Xu, Chao Xiong, Wei Xia, Zhongqiang Cao, Shunqing Xu, Youjie Wang
Summary: Long sleep duration and poor sleep quality during late pregnancy were associated with shorter newborn telomere length.
Article
Environmental Sciences
Xiya Qin, Lulu Song, Gaojie Fan, Qing Liu, Mingyang Wu, Jianing Bi, Qing Fang, Zhengce Wan, Yongman Lv, Youjie Wang
Summary: This study aimed to investigate the effect of metal co-exposure on sex-specific handgrip strength. Linear regression, restricted cubic spline (RCS) model, and weighted quantile sum (WQS) regression were used to evaluate the association of single metal as well as metal mixture with handgrip strength. The results showed that several metallic elements were adversely associated with handgrip strength, especially among men, and cadmium (Cd) may contribute most to the conjunct risk.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)