Review
Clinical Neurology
Luca Prosperini, Valentina Tomassini, Letizia Castelli, Andrea Tacchino, Giampaolo Brichetto, Davide Cattaneo, Claudio Marcello Solaro
Summary: The study found that exergames have a moderate effect on improving balance dysfunction in neurological conditions. Higher frequency interventions were associated with larger effects, but overall intervention duration and session intensity did not affect the outcome. The beneficial effects of exergames may be maintained for at least 4 weeks after discontinuation, but further research is needed to explore this retention effect.
JOURNAL OF NEUROLOGY
(2021)
Review
Neurosciences
Sean L. Thompson, Georgia H. O'Leary, Christopher W. Austelle, Elise Gruber, Alex T. Kahn, Andrew J. Manett, Baron Short, Bashar W. Badran
Summary: Vagus nerve stimulation (VNS) is a well-established form of neuromodulation with potential applications in various disorders, but there is currently a lack of consensus on the optimal stimulation parameters. This therapy has shown promise in treating conditions such as epilepsy, depression, and post-stroke rehabilitation. The article provides a historical perspective on the evolution and applications of VNS in different fields.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Clinical Neurology
Ismael Conejero, Laurent Collombier, Jorge Lopez-Castroman, Thibault Mura, Sandrine Alonso, Emilie Olie, Vincent Boudousq, Fabrice Boulet, Caroline Arquizan, Charlotte Boulet, Anne Wacongne, Camille Heitz, Christel Castelli, Stephane Mouchabac, Philippe Courtet, Mocrane Abbar, Eric Thouvenot
Summary: This study investigates the alterations of resting brain metabolism in motor functional neurological disorder patients and finds associations between brain activity and persistent disability as well as motor recovery.
Review
Geriatrics & Gerontology
Fengwu Li, Xiaokun Geng, Ho Jun Yun, Yazeed Haddad, Yuhua Chen, Yuchuan Ding
Summary: Physical exercise has been shown to induce remodeling and proliferation of astrocytes, which potentially affect the recruitment and function of neurons. The interactions between astrocytes, microglia, and neurons may enhance neuroplasticity, ultimately impacting neural circuit function.
Article
Neurosciences
Sara Izadi-Najafabadi, Jill G. Zwicker
Summary: The study found that children with DCD showed significant improvement in white matter microstructure in multiple brain regions after the Cognitive Orientation to Occupational Performance intervention, which positively affected attention, self-regulation, and motor planning. In contrast, children with co-occurring DCD and ADHD did not show any brain changes following the intervention. Modifications to the treatment protocol might help address the attentional and self-regulatory needs of children with a dual diagnosis.
FRONTIERS IN HUMAN NEUROSCIENCE
(2021)
Editorial Material
Clinical Neurology
Mark J. Edwards
Summary: Patients with medically unexplained or functional symptoms, often avoided by health professionals, may hold the key to a more successful, meaningful, and just system of medical practice. They prompt us to consider the human and participatory aspect of illness, which is often neglected in medical training and practice. There is room for improvement in addressing this aspect in healthcare.
Review
Engineering, Biomedical
Ahad Behboodi, Walker A. Lee, Victoria S. Hinchberger, Diane L. Damiano
Summary: This scoping review examines the effectiveness of BCI-based neurofeedback methods for improving motor outcomes in adults with non-progressive neurological injuries, particularly stroke. The findings confirm previous evidence of the effectiveness of BCI-based neurofeedback training in improving motor outcomes and suggest the potential for enhanced neuroplasticity. The emergence of associative learning paradigms may offer feasible and effective methods for neurorehabilitation. Further clinical trials are needed, particularly in pediatric and adult neurorehabilitation, to refine methods and compare with other evidence-based training strategies.
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2022)
Review
Neurosciences
Robert A. Morrison, Seth A. Hays, Michael P. Kilgard
Summary: Stroke often results in lasting orofacial impairments, and while speech therapy can improve function, many patients only see modest improvements. The combination of vagus nerve stimulation (VNS) with traditional speech therapy holds promise in enhancing recovery of speech motor function post-stroke. Further research and development are needed to establish and optimize this approach for individuals with motor speech disorders.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Orthopedics
Sarah M. Schwab, Sarah Dugan, Michael A. Riley
Summary: Mobility and speech-language impairments in adults with neurological conditions do not manifest in isolated anatomical components, but are task-dependent and require interprofessional care for optimization. Despite the benefits of cotreatment between physical therapists and speech-language pathologists, there are still limitations in this collaboration. Enhanced cotreatment and collaboration between these disciplines can improve function and task-relevant conditions.
Article
Health Care Sciences & Services
Nikolai Shcherbakov, Nataliya Varako, Maria Kovyazina, Yulia Zueva, Maria Baulina, Anatoliy Skvortsov, Daria Chernikova
Summary: This study investigated the effectiveness of group training for executive function disorder rehabilitation in neurological patients. Positive trends were observed in the evaluation methods, although not all reached statistical significance. Results indicated a positive dynamic in the state of executive functions.
Review
Neurosciences
Fang Yu, Tingting Huang, Yuanyuan Ran, Da Li, Lin Ye, Guiqin Tian, Jianing Xi, Zongjian Liu
Summary: This passage discusses the interaction between microglial activation and endogenous neuroplasticity, focusing on plastic alterations in the overall brain network and their implications for structural and functional restoration after stroke. It also summarizes recent advances in the impacts of microglial phenotype polarization on brain plasticity, aiming to discuss the potential efficacy of microglia-based extrinsic restorative interventions in promoting post-stroke recovery.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2021)
Review
Biochemistry & Molecular Biology
Chenye Qiao, Zongjian Liu, Shuyan Qie
Summary: Stroke can cause neurological deficits and dysfunctions at different stages of pathological development. Neuroprotection is the main treatment in the acute phase, while functional recovery becomes the focus in the subacute and chronic phases. Neuroplasticity, including dendritic and axonal remodeling, synapse shaping, and neurogenesis, is considered the basis for post-stroke restoration. Microglia play a crucial role in regulating brain inflammation and neurological recovery after stroke, and their activation and phagocytic function are closely related to neuroplasticity. This review explores the impact of neuroplasticity on post-stroke restoration and discusses the functions and mechanisms of microglial activation, polarization, and phagocytosis, as well as microglia-targeted rehabilitative interventions that promote stroke recovery.
Article
Neurosciences
Kamaldeep K. Gill, Donna Lang, Jill G. Zwicker
Summary: The study aimed to investigate the effects of CO-OP intervention on cerebellar volume in children with DCD. The results showed that children with DCD who received CO-OP intervention demonstrated improved motor outcomes and structural changes in the brain.
Article
Clinical Neurology
Ginger Polich, Stacey Zalanowski, Julie Maney, David L. Perez, Gaston Baslet, Julie Maggio, Mary A. O'Neal, Barbara Dworetzky, Seth Herman
Summary: This article describes the efforts of an inpatient rehabilitation facility to design and implement a clinical pathway for patients with acute-onset motor FND. The article highlights the need for further research to determine the optimal duration and intensity of inpatient rehabilitation treatment for patients with motor FND.
NEUROREHABILITATION
(2022)
Review
Clinical Neurology
Caoimhe McLoughlin, Ingrid Hoeritzauer, Veronica Cabreira, Selma Aybek, Caitlin Adams, Jane Alty, Harriet A. Ball, Janet Baker, Kim Bullock, Chrissie Burness, Barbara A. Dworetzky, Sara Finkelstein, Beatrice Garcin, Jeannette Gelauff, Laura H. Goldstein, Anika Jordbru, Anne-Catherine M. L. Huys, Aoife Laffan, Sarah C. Lidstone, Stefanie Caroline Linden, Lea Ludwig, Julie Maggio, Francesca Morgante, Elizabeth Mallam, Clare Nicholson, Mary O'Neal, Suzanne O'Sullivan, Isabel Parees, Panayiota Petrochilos, Susannah Pick, Wendy Phillips, Karin Roelofs, Rachel Newby, Biba Stanton, Cordelia Gray, Eileen M. Joyce, Marina A. J. Tijssen, Trudie Chalder, Maxanne McCormick, Paula Gardiner, Indrit Begue, Margaret C. Tuttle, Isobel Williams, Sarah McRae, Valerie Voon, Laura McWhirter
Summary: Functional neurological disorder (FND) is often overlooked and misunderstood by clinicians, despite being a common and accurately diagnosable condition based on clinical signs. People with FND face discrimination from healthcare providers, researchers, and the public, reflecting the neglect of disorders primarily affecting women. We argue that FND is a feminist issue, drawing on historical and contemporary perspectives from clinical, research, and social domains. We call for equal attention and support for FND in medical education, research, and clinical services to ensure adequate care for those affected.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2023)
Article
Clinical Neurology
Maya G. Panisset, Doa El-Ansary, Sarah Alison Dunlop, Ruth Marshall, Jillian Clark, Leonid Churilov, Mary P. Galea
Summary: This study conducted a per-protocol analysis on thigh muscle volume outcomes in patients with spinal cord injury who participated in functional electrical stimulation-assisted cycling or passive cycling for 12 weeks. The results showed that 42% of the patients had a partial response and 25% had a beneficial response, regardless of the mode of intervention. The study also found a significant correlation between exercise frequency and thigh muscle volumes.
JOURNAL OF SPINAL CORD MEDICINE
(2022)
Article
Rehabilitation
Julie Louie, Katherine Baquie, Justin Offerman, Catherine L. Granger, Fary Khan, Kelly J. Bower
Summary: The study aimed to investigate the feasibility and preliminary efficacy of a group self-management exercise and education program for people with multiple sclerosis. The results showed that the program was feasible and safe, with high adherence rates for exercise and education sessions. The intervention group demonstrated positive changes in walking endurance, Functional Reach, and fatigue compared to the control group.
CLINICAL REHABILITATION
(2022)
Review
Clinical Neurology
Bhasker Amatya, Fary Khan
Summary: The evidence for the effect of dietary interventions on MS-related health outcomes is currently uncertain.
NEUROREHABILITATION
(2022)
Review
Public, Environmental & Occupational Health
Jean Wu, Michael McCullough, Maya G. Panisset, Mary P. Galea
Summary: Musculoskeletal disorders (MSDs) are common among dental professionals. Current evidence suggests that the use of ergonomic equipment can help prevent MSDs, but there are knowledge gaps in the areas of exercise, therapy, and education.
WORK-A JOURNAL OF PREVENTION ASSESSMENT & REHABILITATION
(2022)
Article
Rehabilitation
Marlena Klaic, Justin Fong, Vincent Crocher, Katie Davies, Kim Brock, Emma Sutton, Denny Oetomo, Ying Tan, Mary P. Galea
Summary: This study aimed to identify the factors influencing clinician adoption of robotic devices into practice by using the technology acceptance model as a framework. The results showed that rehabilitation clinicians perceived robotic devices as complex to use, which influenced their intention to use them. Lack of experience and time to learn also affected their confidence to implement robotic devices into practice. Therefore, improving perceived usefulness and ease of use through experience, training, and embedded technological support is necessary.
DISABILITY AND REHABILITATION-ASSISTIVE TECHNOLOGY
(2022)
Review
Rehabilitation
Bhasker Amatya, Fary Khan
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2023)
Article
Clinical Neurology
Jamie Ellis, Erin Garner, Kate E. Webster, Susan Darzins, Mary P. Galea, Adam Scheinberg
Summary: This study collected perspectives on the development of a national register for pediatric spinal cord disorders and developed a minimum dataset for an Australian register. It is recommended to link the pediatric register to an adult database to ensure coverage across the lifespan. Review and refinement of the minimum dataset are suggested to make it more practical for use.
JOURNAL OF SPINAL CORD MEDICINE
(2022)
Review
Multidisciplinary Sciences
Vandana Vasudevan, Bhasker Amatya, Fary Khan
Summary: There is limited evidence to guide clinicians in managing common complications associated with Traumatic Brain Injury (TBI). A systematic review of published studies on the management of common TBI complications found that only a few studies met the criteria. The findings suggest that anti-epileptic drugs may be beneficial in reducing seizure incidence, but more research is needed for other TBI-related complications.
Article
Rehabilitation
Bhasker Amatya, Michael Dickinson, Fary Khan
Summary: This study assessed the long-term outcomes in terms of function, psychosocial well-being, and participation in a cohort of non-Hodgkin lymphoma (NHL) survivors in Australia. The findings showed that despite good functional recovery and adjustment in the community, survivors reported ongoing physical and cognitive issues, highlighting the need for long-term rehabilitation-inclusive management.
JOURNAL OF REHABILITATION MEDICINE
(2023)
Review
Rehabilitation
Bhasker Amatya, Fary Khan
Summary: With the increasing frequency of disasters, the importance of rehabilitation in disaster management is being recognized. However, rehabilitation is still not prioritized in disaster management, despite evidence supporting its early involvement. Strong leadership and effective action are needed to strengthen rehabilitation capacity and implement comprehensive disaster management plans.
ANNALS OF REHABILITATION MEDICINE-ARM
(2023)
Article
Rehabilitation
Bhasker Amatya, Alaeldin Elmalik, Krystal Song, Su Yi Lee, Mary P. Galea, Fary Khan
Summary: The study examined the responsiveness of the ICF ClinFIT in routine clinical practice in Australia. The results showed that ClinFIT is useful in evaluating patient functioning and can detect changes in functioning over time and across different health conditions.
JOURNAL OF REHABILITATION MEDICINE
(2022)
Article
Rehabilitation
Bhasker Amatya, Alaeldin Elmalik, Su Yi Lee, Krystal Song, Mary P. Galea, Fary Khan
Summary: The modified Post-Stroke Checklist (mPSC) is a feasible tool in inpatient rehabilitation settings to identify stroke-related problems and facilitate targeted intervention. In this study, the mPSC was administered at hospital discharge and 3 months post-discharge, and it successfully identified the majority of stroke-related problems. Participants showed improvement in function after targeted interventions such as physiotherapy and occupational therapy.
JOURNAL OF REHABILITATION MEDICINE
(2022)