Nanocapillary sampling coupled to liquid chromatography mass spectrometry delivers single cell drug measurement and lipid fingerprints

On-capillary Cell Lysis Enables Top-down Proteomic Analysis of Single Mammalian Cells by CE-MS/MS

(2022) Kendall R. Johnson et al.   ANALYTICAL CHEMISTRY

Anomalous collapses of Nares Strait ice arches leads to enhanced export of Arctic sea ice

(2021) G. W. K. Moore et al.   Nature Communications

Correlative light electron ion microscopy reveals in vivo localisation of bedaquiline in Mycobacterium tuberculosis–infected lungs

(2021) Antony Fearns et al.   PLOS BIOLOGY

Spatially Resolved Mass Spectrometry at the Single Cell: Recent Innovations in Proteomics and Metabolomics

(2021) Michael J. Taylor et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

High‐throughput Single‐cell Mass Spectrometry Reveals Abnormal Lipid Metabolism in Pancreatic Ductal Adenocarcinoma

(2021) Qinlei Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multiplexed single-cell proteomics using SCoPE2

(2021) Aleksandra A. Petelski et al.   Nature Protocols

Lipidomics reveals carnitine palmitoyltransferase 1C protects cancer cells from lipotoxicity and senescence

(2020) Huizhen Zhang et al.   Journal of Pharmaceutical Analysis

Imaging Mass Spectrometry Reveals Tumor Metabolic Heterogeneity

(2020) Yang Zhang et al.   iScience

Single-cell screening of tamoxifen abundance and effect using mass spectrometry and Raman-spectroscopy

(2019) Ahmed Ali et al.   ANALYTICAL CHEMISTRY

Accurate mass and retention time library of serum lipids for type 1 diabetes research

(2019) Ngoc Vu et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Nanoextraction Coupled to Liquid Chromatography Mass Spectrometry Delivers Improved Spatially Resolved Analysis

(2019) Holly-May Lewis et al.   ANALYTICAL CHEMISTRY

Relative bioavailability of bedaquiline tablets suspended in water: implications for dosing in children

(2018) Elin M. Svensson et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Single-Cell Mass Spectrometry Reveals Changes in Lipid and Metabolite Expression in RAW 264.7 Cells upon Lipopolysaccharide Stimulation

(2018) Bo Yang et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Application of Various Normalization Methods for Microscale Analysis of Tissues Using Direct Analyte Probed Nanoextraction

(2018) Janella de Jesus et al.   ANALYTICAL CHEMISTRY

Live single cell mass spectrometry reveals cancer‐specific metabolic profiles of circulating tumor cells

(2018) Yasmine Abouleila et al.   CANCER SCIENCE

DAPNe with micro-capillary separatory chemistry-coupled to MALDI-MS for the analysis of polar and non-polar lipid metabolism in one cell

(2017) Jason S. Hamilton et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

The 3D OrbiSIMS—label-free metabolic imaging with subcellular lateral resolution and high mass-resolving power

(2017) Melissa K Passarelli et al.   NATURE METHODS

Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness

(2017) Michiru Nishita et al.   Scientific Reports

Phytochemical profiling in single plant cell by high performance liquid chromatography-mass spectrometry

(2016) Fang Yuan et al.   ANALYST

Fast Single-Cell Patterning for Study of Drug-Induced Phenotypic Alterations of HeLa Cells Using Time-of-Flight Secondary Ion Mass Spectrometry

(2016) Lu Huang et al.   ANALYTICAL CHEMISTRY

Development of Visible-Wavelength MALDI Cell Mass Spectrometry for High-Efficiency Single-Cell Analysis

(2016) Caiqiao Xiong et al.   ANALYTICAL CHEMISTRY

Recent Advances in the Analysis of Single Cells

(2016) Lucas Armbrecht et al.   ANALYTICAL CHEMISTRY

Inflammatory signaling in human tuberculosis granulomas is spatially organized

(2016) Mohlopheni J Marakalala et al.   NATURE MEDICINE

A lipidomics demonstration of the importance of single cell analysis

(2015) Mandy S. Phelps et al.   Analytical Methods

Nanomanipulation-Coupled Matrix-Assisted Laser Desorption/ Ionization-Direct Organelle Mass Spectrometry: A Technique for the Detailed Analysis of Single Organelles

(2015) Mandy S. Phelps et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

The Single-Probe: A Miniaturized Multifunctional Device for Single Cell Mass Spectrometry Analysis

(2014) Ning Pan et al.   ANALYTICAL CHEMISTRY

Bedaquiline: a review of human pharmacokinetics and drug-drug interactions

(2014) R. P. G. van Heeswijk et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Nanomanipulation-coupled nanospray mass spectrometry as an approach for single cell analysis

(2014) Mandy Phelps et al.   REVIEW OF SCIENTIFIC INSTRUMENTS

Single-Cell Lipidomics: Characterizing and Imaging Lipids on the Surface of Individual Aplysia californica Neurons with Cluster Secondary Ion Mass Spectrometry

(2013) Melissa K. Passarelli et al.   ANALYTICAL CHEMISTRY

Direct Drug Metabolism Monitoring in a Live Single Hepatic Cell by Video Mass Spectrometry

(2012) Sachiko DATE et al.   ANALYTICAL SCIENCES

Metabolite analyses of single cells

(2012) Akira Oikawa et al.   PLANT JOURNAL

Compositional Mapping of the Surface and Interior of Mammalian Cells at Submicrometer Resolution

(2011) Christopher Szakal et al.   ANALYTICAL CHEMISTRY

Single-Cell MALDI-MS as an Analytical Tool for Studying Intrapopulation Metabolic Heterogeneity of Unicellular Organisms

(2010) Andrea Amantonico et al.   ANALYTICAL CHEMISTRY

Mass Spectrometric Imaging for Biomedical Tissue Analysis

(2010) Kamila Chughtai et al.   CHEMICAL REVIEWS

Live Single-cell Mass Spectrometry

(2009) Tsutomu MASUJIMA   ANALYTICAL SCIENCES

Quantitative Measurements of Cell−Cell Signaling Peptides with Single-Cell MALDI MS

(2008) Stanislav S. Rubakhin et al.   ANALYTICAL CHEMISTRY

Live Single-Cell Molecular Analysis by Video-Mass Spectrometry

(2008) Naohiro TSUYAMA et al.   ANALYTICAL SCIENCES