Etifoxine improves sensorimotor deficits and reduces glial activation, neuronal degeneration, and neuroinflammation in a rat model of traumatic brain injury
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Title
Etifoxine improves sensorimotor deficits and reduces glial activation, neuronal degeneration, and neuroinflammation in a rat model of traumatic brain injury
Authors
Keywords
Traumatic brain injury, Etifoxine, Neuroinflammation, TSPO, Neurosteroids, Functional recovery, Cytokines, Astrogliosis, Neuronal degeneration, Microglia
Journal
Journal of Neuroinflammation
Volume 13, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-08-26
DOI
10.1186/s12974-016-0687-3
References
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Note: Only part of the references are listed.- Microglia in the TBI brain: The good, the bad, and the dysregulated
- (2016) David J. Loane et al. EXPERIMENTAL NEUROLOGY
- Differential efficacy of the TSPO ligands etifoxine and XBD-173 in two rodent models of Multiple Sclerosis
- (2016) Brinda Ravikumar et al. NEUROPHARMACOLOGY
- Etifoxine Versus Alprazolam for the Treatment of Adjustment Disorder with Anxiety: a Randomized Controlled Trial
- (2015) Dan J. Stein ADVANCES IN THERAPY
- Acute neuroinflammation in a clinically relevant focal cortical ischemic stroke model in rat: longitudinal positron emission tomography and immunofluorescent tracking
- (2015) Miklós Tóth et al. Brain Structure & Function
- Biomarkers of Traumatic Injury Are Transported from Brain to Blood via the Glymphatic System
- (2015) B. A. Plog et al. JOURNAL OF NEUROSCIENCE
- Temporal profile of M1 and M2 responses in the hippocampus following early 24h of neurotrauma
- (2015) Mubeen A. Ansari JOURNAL OF THE NEUROLOGICAL SCIENCES
- Enhancing neurosteroid synthesis – Relationship to the pharmacology of translocator protein (18 kDa) (TSPO) ligands and benzodiazepines
- (2015) L Wolf et al. PHARMACOPSYCHIATRY
- The Non-Benzodiazepine Anxiolytic Drug Etifoxine Causes a Rapid, Receptor-Independent Stimulation of Neurosteroid Biosynthesis
- (2015) Jean Luc do Rego et al. PLoS One
- Oxidative Stress in Traumatic Brain Injury
- (2014) Ana Rodriguez-Rodriguez et al. CURRENT MEDICINAL CHEMISTRY
- PET imaging of neuroinflammation in a rat traumatic brain injury model with radiolabeled TSPO ligand DPA-714
- (2014) Yu Wang et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Macrophagic and microglial responses after focal traumatic brain injury in the female rat
- (2014) L Turtzo et al. Journal of Neuroinflammation
- Reduced GABAergic Inhibition in the Basolateral Amygdala and the Development of Anxiety-Like Behaviors after Mild Traumatic Brain Injury
- (2014) Camila P. Almeida-Suhett et al. PLoS One
- A TSPO ligand is protective in a mouse model of multiple sclerosis
- (2013) Daniel J. Daugherty et al. EMBO Molecular Medicine
- Traumatic brain injury induces macrophage subsets in the brain
- (2013) Christine L. Hsieh et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Minocycline plus N-acetylcysteine synergize to modulate inflammation and prevent cognitive and memory deficits in a rat model of mild traumatic brain injury
- (2013) Margalit Haber et al. EXPERIMENTAL NEUROLOGY
- Microglia/Macrophage Polarization Dynamics in White Matter after Traumatic Brain Injury
- (2013) Guohua Wang et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Inflammatory Consequences in a Rodent Model of Mild Traumatic Brain Injury
- (2013) J. Regino Perez-Polo et al. JOURNAL OF NEUROTRAUMA
- Revisiting the roles of progesterone and allopregnanolone in the nervous system: Resurgence of the progesterone receptors
- (2013) M. Schumacher et al. PROGRESS IN NEUROBIOLOGY
- Three-dimensional Confocal Analysis of Microglia/macrophage Markers of Polarization in Experimental Brain Injury
- (2013) Carlo Perego et al. Jove-Journal of Visualized Experiments
- Microglia Activation as a Biomarker for Traumatic Brain Injury
- (2013) Diana G. Hernandez-Ontiveros et al. Frontiers in Neurology
- The Role of Markers of Inflammation in Traumatic Brain Injury
- (2013) Thomas Woodcock et al. Frontiers in Neurology
- Decreased neuroinflammation and increased brain energy homeostasis following environmental enrichment after mild traumatic brain injury is associated with improvement in cognitive function
- (2013) Teresita L Briones et al. Acta Neuropathologica Communications
- Neuroinflammation after traumatic brain injury: Opportunities for therapeutic intervention
- (2012) Alok Kumar et al. BRAIN BEHAVIOR AND IMMUNITY
- Treatment of Mild Traumatic Brain Injury with an Erythropoietin-Mimetic Peptide
- (2012) Claudia S. Robertson et al. JOURNAL OF NEUROTRAUMA
- The cytokine temporal profile in rat cortex after controlled cortical impact
- (2012) Clifton L. Dalgard et al. Frontiers in Molecular Neuroscience
- Axonal Regeneration and Neuroinflammation: Roles for the Translocator Protein 18 kDa
- (2011) C. Girard et al. JOURNAL OF NEUROENDOCRINOLOGY
- The Effect of Progesterone Dose on Gene Expression after Traumatic Brain Injury
- (2011) Gail D. Anderson et al. JOURNAL OF NEUROTRAUMA
- Cytokines and innate inflammation in the pathogenesis of human traumatic brain injury
- (2011) Adel Helmy et al. PROGRESS IN NEUROBIOLOGY
- A Neurovascular Perspective for Long-Term Changes After Brain Trauma
- (2011) V. Pop et al. Translational Stroke Research
- Early TBI-Induced Cytokine Alterations are Similarly Detected by Two Distinct Methods of Multiplex Assay
- (2011) Sanjib Mukherjee et al. Frontiers in Molecular Neuroscience
- COG1410, an apolipoprotein E-based peptide, improves cognitive performance and reduces cortical loss following moderate fluid percussion injury in the rat
- (2010) Nicholas A. Kaufman et al. BEHAVIOURAL BRAIN RESEARCH
- In vivo imaging of neuroinflammation in the rodent brain with [11C]SSR180575, a novel indoleacetamide radioligand of the translocator protein (18 kDa)
- (2010) Fabien Chauveau et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Role of CCL2 (MCP-1) in Traumatic Brain Injury (TBI): Evidence from Severe TBI Patients and CCL2−/− Mice
- (2010) Bridgette D Semple et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders
- (2010) Rainer Rupprecht et al. NATURE REVIEWS DRUG DISCOVERY
- Involvement of pro- and anti-inflammatory cytokines and chemokines in the pathophysiology of traumatic brain injury
- (2010) Jenna M. Ziebell et al. Neurotherapeutics
- Treadmill exercise inhibits traumatic brain injury-induced hippocampal apoptosis
- (2010) Dong-Hyun Kim et al. PHYSIOLOGY & BEHAVIOR
- Translocator protein (18 kDa) TSPO: An emerging therapeutic target in neurotrauma
- (2009) Vassilios Papadopoulos et al. EXPERIMENTAL NEUROLOGY
- PREVENTIVE AND CURATIVE EFFECTS OF ETIFOXINE IN A RAT MODEL OF BRAIN OEDEMA
- (2008) Philippe Girard et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Traumatic brain injury causes a long-lasting calcium (Ca2+)-plateau of elevated intracellular Ca levels and altered Ca2+homeostatic mechanisms in hippocampal neurons surviving brain injury
- (2008) David A. Sun et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Etifoxine improves peripheral nerve regeneration and functional recovery
- (2008) C. Girard et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Acute, regional inflammatory response after traumatic brain injury: Implications for cellular therapy
- (2008) Matthew T. Harting et al. SURGERY
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