Exosomes derived from atorvastatin-modified bone marrow dendritic cells ameliorate experimental autoimmune myasthenia gravis by up-regulated levels of IDO/Treg and partly dependent on FasL/Fas pathway

Simvastatin Prevents and Reverses Depigmentation in a Mouse Model of Vitiligo

(2015) Priti Agarwal et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Immature dendritic cell exosomes suppress experimental autoimmune myasthenia gravis

(2015) Ning Bu et al.   JOURNAL OF NEUROIMMUNOLOGY

Histone deacetylase inhibition regulates inflammation and enhances Tregs after allogeneic hematopoietic cell transplantation in humans

(2014) S. W. Choi et al.   BLOOD

Elevation of MMP-9 and IDO induced by pancreatic cancer cells mediates natural killer cell dysfunction

(2014) Yun-Peng Peng et al.   BMC CANCER

Exosomes As a Short-Range Mechanism to Spread Alloantigen between Dendritic Cells during T Cell Allorecognition

(2014) A. Montecalvo et al.   JOURNAL OF IMMUNOLOGY

Emerging role of extracellular vesicles in inflammatory diseases

(2014) Edit I. Buzas et al.   Nature Reviews Rheumatology

GCN2 kinase plays an important role triggering the remission phase of experimental autoimmune encephalomyelitis (EAE) in mice

(2013) Heloisa Orsini et al.   BRAIN BEHAVIOR AND IMMUNITY

Statins can induce myasthenia gravis

(2013) Jesse Gale et al.   JOURNAL OF CLINICAL NEUROSCIENCE

New treatments for myasthenia: a focus on antisense oligonucleotides

(2013) Corrado Angelini et al.   Drug Design Development and Therapy

A distinct tolerogenic subset of splenic IDO+CD11b+ dendritic cells from orally tolerized mice is responsible for induction of systemic immune tolerance and suppression of collagen-induced arthritis

(2012) Min-Jung Park et al.   CELLULAR IMMUNOLOGY

Plasma-derived MHC class II+ exosomes from tumor-bearing mice suppress tumor antigen-specific immune responses

(2012) Chenjie Yang et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Treatment of Myasthenia Gravis Based on Its Immunopathogenesis

(2012) Jee Young Kim et al.   Journal of Clinical Neurology

CD4+ T cell-released exosomes inhibit CD8+ cytotoxic T-lymphocyte responses and antitumor immunity

(2011) Haifeng Zhang et al.   Cellular & Molecular Immunology

Introduction of theCIITAgene into tumor cells produces exosomes with enhanced anti-tumor effects

(2011) Yeong Shin Lee et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Physiologic Control of the Functional Status of Foxp3+ Regulatory T Cells

(2011) A. L. Mellor et al.   JOURNAL OF IMMUNOLOGY

Tumor-Derived Exosomes Confer Antigen-Specific Immunosuppression in a Murine Delayed-Type Hypersensitivity Model

(2011) Chenjie Yang et al.   PLoS One

Gut CD103+ dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction

(2010) G. Matteoli et al.   GUT

Reprogrammed Foxp3+ Regulatory T Cells Provide Essential Help to Support Cross-presentation and CD8+ T Cell Priming in Naive Mice

(2010) Madhav D. Sharma et al.   IMMUNITY

Exosomes Derived from Immature Bone Marrow Dendritic Cells Induce Tolerogenicity of Intestinal Transplantation in Rats

(2010) Xiaojun Yang et al.   JOURNAL OF SURGICAL RESEARCH

Therapeutic effect of exosomes from indoleamine 2,3-dioxygenase-positive dendritic cells in collagen-induced arthritis and delayed-type hypersensitivity disease models

(2009) Nicole R. Bianco et al.   ARTHRITIS AND RHEUMATISM

Interferon- -triggered indoleamine 2,3-dioxygenase competence in human monocyte-derived dendritic cells induces regulatory activity in allogeneic T cells

(2009) B. Jurgens et al.   BLOOD

Increased immunopotency of monocyte derived dendritic cells from patients with optic neuritis is inhibited in vitro by simvastatin

(2009) Anna Tsakiri et al.   EXPERIMENTAL NEUROLOGY

Suppression of ongoing experimental autoimmune myasthenia gravis by transfer of RelB-silenced bone marrow dentritic cells is associated with a change from a T helper Th17/Th1 to a Th2 and FoxP3+ regulatory T-cell profile

(2009) Huan Yang et al.   INFLAMMATION RESEARCH

Etanercept Treatment in Myasthenia Gravis

(2008) Julie Rowin   Annals of the New York Academy of Sciences

Exosomes as a tumor immune escape mechanism: possible therapeutic implications

(2008) Thomas E Ichim et al.   Journal of Translational Medicine

Statins may aggravate myasthenia gravis

(2008) Shin J. Oh et al.   MUSCLE & NERVE

Different types of in vitro generated human monocyte-derived dendritic cells release exosomes with distinct phenotypes

(2007) Sara M. Johansson et al.   IMMUNOLOGY