Dexmedetomidine Postconditioning Reduces Brain Injury after Brain Hypoxia-Ischemia in Neonatal Rats

Dexmedetomidine improves early postoperative cognitive dysfunction in aged mice

(2015) Xiao-Lan Qian et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Autoregulation of Inducible Nitric Oxide Synthase Expression by RNA Interference Provides Neuroprotection in Neonatal Rats

(2015) Zhi Wang et al.   Theranostics

Inhibition of Brain Ischemia-Caused Notch Activation in Microglia May Contribute to Isoflurane Postconditioning-Induced Neuroprotection in Male Rats

(2014) Jinbo Yin et al.   CNS & Neurological Disorders-Drug Targets

Perineural Dexmedetomidine Attenuates Inflammation in Rat Sciatic Nerve via the NF-κB Pathway

(2014) Yan Huang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Intranasal pyrrolidine dithiocarbamate decreases brain inflammatory mediators and provides neuroprotection after brain hypoxia–ischemia in neonatal rats

(2013) Zhi Wang et al.   EXPERIMENTAL NEUROLOGY

Isoflurane postconditioning reduces ischemia-induced nuclear factor-κB activation and interleukin 1β production to provide neuroprotection in rats and mice

(2013) Hong Li et al.   NEUROBIOLOGY OF DISEASE

Dexmedetomidine is neuroprotective in an in vitro model for traumatic brain injury

(2012) Marc Schoeler et al.   BMC Neurology

Both PI3K/Akt and ERK1/2 pathways participate in the protection by dexmedetomidine against transient focal cerebral ischemia/reperfusion injury in rats

(2012) Yong-Man Zhu et al.   BRAIN RESEARCH

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Pyrrolidine dithiocarbamate attenuates brain Aβ increase and improves long-term neurological outcome in rats after transient focal brain ischemia

(2011) Jiejie Li et al.   NEUROBIOLOGY OF DISEASE

Isoflurane induces hippocampal cell injury and cognitive impairments in adult rats

(2011) Daowei Lin et al.   NEUROPHARMACOLOGY

The combined neuroprotective effects of lidocaine and dexmedetomidine after transient forebrain ischemia in rats

(2009) T. GOYAGI et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Dexmedetomidine provides cortical neuroprotection: impact on anaesthetic-induced neuroapoptosis in the rat developing brain

(2009) R. D. SANDERS et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Dexmedetomidine-induced cerebral hypoperfusion exacerbates ischemic brain injury in rats

(2009) Takaaki Nakano et al.   Journal of Anesthesia

Inflammatory mechanisms in ischemic stroke: therapeutic approaches

(2009) Shaheen E Lakhan et al.   Journal of Translational Medicine

Isoflurane preconditioning improves short-term and long-term neurological outcome after focal brain ischemia in adult rats

(2009) L. Li et al.   NEUROSCIENCE

Moderate Hypothermia to Treat Perinatal Asphyxial Encephalopathy

(2009) Denis V. Azzopardi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Animal Models of Perinatal Hypoxic-Ischemic Brain Damage

(2009) Jerome Y. Yager et al.   PEDIATRIC NEUROLOGY

Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations

(2009) Marc Fisher et al.   STROKE

The neuroprotective effect of dexmedetomidine in the hippocampus of rabbits after subarachnoid hemorrhage

(2008) Murat Cosar et al.   SURGICAL NEUROLOGY