Review
Chemistry, Analytical
Andrea Demeco, Laura Zola, Antonio Frizziero, Chiara Martini, Arrigo Palumbo, Ruben Foresti, Giovanni Buccino, Cosimo Costantino
Summary: In recent years, new technologies, such as fully immersive virtual reality (FIVR), have been applied in stroke rehabilitation alongside conventional techniques. This study aimed to investigate the effectiveness of FIVR in stroke rehabilitation. A total of 12 randomized controlled trials (RCTs) involving 350 post-acute and chronic stroke survivors were included, and the results showed that FIVR provides additional benefits compared to standard rehabilitation, improving upper limb dexterity, gait performance, and dynamic balance, and influencing patient independence. Therefore, FIVR represents a versatile rehabilitation tool that can improve treatment compliance and the functioning and quality of life of stroke survivors.
Review
Behavioral Sciences
Adriana Salatino, Claudio Zavattaro, Roberto Gammeri, Emanuele Cirillo, Maria Luisa Piatti, Maria Pyasik, Hilary Serra, Lorenzo Pia, Giuliano Geminiani, Raffaella Ricci
Summary: In recent decades, new virtual reality (VR)-based protocols have been proposed for the rehabilitation of Unilateral Spatial Neglect (USN). However, the optimal type of VR protocol and level of immersion remain unclear. In this systematic review, 26 studies were identified and improvements were found in 84.6% of the reviewed studies. Further randomized control trials are needed to validate the clinical efficacy of VR protocols for USN rehabilitation.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Article
Medicine, General & Internal
Janita Pak Chun Chau, Suzanne Hoi Shan Lo, Alexander Yuk Lun Lau, Vivian Wing Yan Lee, Kai Chow Choi, Eddie Chi Fai Kwok, David R. Thompson
Summary: This study aims to develop and evaluate the effectiveness of a social participation-focused virtual reality intervention on the physical, psychological, and social outcomes of community-dwelling stroke survivors with physical disabilities. A randomized controlled clinical trial will be conducted with 250 stroke survivor-caregiver pairs, and data will be collected at baseline, immediately after the intervention, and 3 months later.
Editorial Material
Computer Science, Information Systems
Francesco Arcuri, Camillo Porcaro, Irene Ciancarelli, Paolo Tonin, Antonio Cerasa
Summary: This review discusses the use of EEG as a neuroimaging method for extracting neuroplasticity in stroke patients undergoing VR rehabilitation, highlighting the challenges and potential benefits of combining VR therapy with EEG analysis.
Article
Medicine, General & Internal
Marie Bougeard, Isabelle Hauret, Mathilde Pelletier-Visa, Anne Plan-Paquet, Pascale Givron, Marin Badin, Bruno Pereira, Charlotte Lanhers, Emmanuel Coudeyre
Summary: Botulinum toxin injection is a common method to reduce spasticity caused by central neurological damage. Immersive virtual reality can help adults cope with the stress and pain of botulinum toxin treatment injection.
Review
Rehabilitation
Jie Hao, Haoyu Xie, Kimberly Harp, Zhen Chen, Ka-Chun Siu
Summary: This article systematically reviews and examines the effects of virtual reality (VR)-based rehabilitation on neural plasticity changes in survivors of stroke. The main neurophysiological changes observed after VR intervention include improved interhemispheric balance, enhanced cortical connectivity, increased cortical mapping of the affected limb muscles, increased activation of regions in the frontal cortex, and possible involvement of the mirror neuron system. This suggests that VR-based rehabilitation has a positive impact on neural plasticity changes in stroke survivors.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Article
Health Care Sciences & Services
Andy Wai Kan Yeung, Anela Tosevska, Elisabeth Klager, Fabian Eibensteiner, Daniel Laxar, Jivko Stoyanov, Marija Glisic, Sebastian Zeiner, Stefan Tino Kulnik, Rik Crutzen, Oliver Kimberger, Maria Kletecka-Pulker, Atanas G. Atanasov, Harald Willschke
Summary: Using a bibliometric approach, this study analyzed the scientific literature on VR and AR research in medicine, revealing that major themes include diagnostic and surgical procedures, as well as the investigation of medical conditions such as pain, stroke, anxiety, depression, fear, cancer, and neurodegenerative disorders. Contributions to the literature were globally distributed, with the United States and United Kingdom being the top contributors.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Engineering, Biomedical
Gauthier Everard, Yasmine Otmane-Tolba, Zelie Rosselli, Thomas Pellissier, Khawla Ajana, Stephanie Dehem, Edouard Auvinet, Martin Gareth Edwards, Julien Lebleu, Thierry Lejeune
Summary: This study developed an immersive virtual reality version of the Box and Block Test (BBT-VR) and assessed its concurrent validity and usability among patients with stroke and healthy participants. The results showed that BBT-VR is a reliable test that can effectively evaluate manual dexterity and provide kinematic parameters.
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2022)
Review
Engineering, Biomedical
Jamille A. Feitosa, Corina A. Fernandes, Raphael F. Casseb, Gabriela Castellano
Summary: Virtual reality (VR) rehabilitation has been shown to improve motor and cognitive abilities in different populations. This study systematically reviewed the effects of VR intervention on cortical reorganization and functional improvement. The results demonstrated changes in brain activation and reorganization patterns in stroke patients, older adults, and patients with other neurological conditions, which were associated with functional improvement after VR intervention.
JOURNAL OF NEURAL ENGINEERING
(2022)
Review
Rehabilitation
Yi Li, Jiashang Huang, Xiaohong Li, Jia Qiao, Xin Huang, Lining Yang, Heping Yu
Summary: This study found that virtual reality (VR) is more effective than time-dose-matched conventional therapy (CT) in recovering upper limb motor function in stroke patients, especially when a virtual environment is used or VR is mixed with CT. However, VR (VR only or mixed with CT) does not improve patients' daily activity performance and participation compared with CT. Overall, VR appears to be safe and acceptable as CT.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Article
Rehabilitation
Busra Kayabinar, Ipek Alemdaroglu-Gurbuz, Oznur Yilmaz
Summary: This study found that VR augmented RAGT improved dual-task gait speeds and dual-task performance in chronic stroke patients, but there were no significant differences between the two groups after the treatment.
EUROPEAN JOURNAL OF PHYSICAL AND REHABILITATION MEDICINE
(2021)
Article
Computer Science, Information Systems
Che-Wei Lin, Li-Chieh Kuo, Yu-Ching Lin, Fong-Chin Su, Yu-An Lin, Hsiu-Yun Hsu
Summary: The study found that the virtual reality mirror therapy system has a positive impact on the sensorimotor performance of hands in healthy participants, and also provides beneficial effects on motor function of the upper extremity in chronic stroke patients.
Article
Neurosciences
Joon-Ho Shin, Mingyu Kim, Ji-Yeong Lee, Mi-Young Kim, Yu-Jin Jeon, Kwanguk Kim
Summary: In this study, a virtual reality-visual exploration therapy combining elements from the FOPR test and visual exploration therapy (VET) was developed for HSN rehabilitation following stroke. The VR-VET significantly improved clinical assessments and FOPR test results compared to waiting without VR-VET, with more pronounced improvements in the left hemispace.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Medicine, General & Internal
Zhi-Qing Zhou, Xu-Yun Hua, Jia-Jia Wu, Jing-Jing Xu, Meng Ren, Chun-Lei Shan, Jian-Guang Xu
Summary: This study aims to explore the effectiveness and neurological mechanisms of combining robot motor assistance and neural circuit-based virtual reality lower extremity rehabilitation training in patients after stroke.
Article
Medicine, General & Internal
Birgit Maria Vahlberg, Erik Lundstrom, Staffan Eriksson, Ulf Holmback, Tommy Cederholm
Summary: The study evaluated the effects of mobile phone text-messaging exercise instructions on body composition, cardiometabolic risk markers, and self-reported health at 3 months after stroke. The results showed no clear effect of daily mobile phone-delivered training instructions on body composition, cardiovascular biochemical risk factors, or self-perceived health. Further research is needed to evaluate secondary prevention efforts in larger populations after recent stroke.
Review
Clinical Neurology
Marc W. Slutzky
Article
Clinical Neurology
Jing Xu, Meret Branscheidt, Heidi Schambra, Levke Steiner, Mario Widmer, Jorn Diedrichsen, Jeff Goldsmith, Martin Lindquist, Tomoko Kitago, Andreas R. Luft, John W. Krakauer, Pablo A. Celnik
ANNALS OF NEUROLOGY
(2019)
Article
Clinical Neurology
Nick S. Ward, Fran Brander, Kate Kelly
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2019)
Article
Engineering, Biomedical
Martina Maier, Belen Rubio Ballester, Nuria Banuelos, Esther Oller, Paul F. M. J. Verschure
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2020)
Review
Neurosciences
Silvestro Micera, Matteo Caleo, Carmelo Chisari, Friedhelm C. Hummel, Alessandra Pedrocchi
Article
Chemistry, Analytical
Jingjing Luo, Junjie Zhen, Peng Zhou, Wei Chen, Yuzhu Guo
Summary: This study developed a video-based facial iPPG detecting equipment that provides multi-dimensional spatiotemporal hemodynamic pulsations for high portability and self-monitoring needs. A series of algorithms were also created for physiological indices extraction and visualization of hemodynamic pulsation distribution. The new device offers a reliable measurement of cardiovascular hemodynamics and, combined with advanced computing techniques, presents a promising solution for user-friendly pervasive healthcare.
Article
Neurosciences
Chenxi Chu, Jingjing Luo, Xiwei Tian, Xiangke Han, Shijie Guo
Summary: This study introduced a novel tactile-stimuli P300 paradigm for BCI targeting individuals with learning difficulties or attention deficits. The paradigm utilized a combination of spatial and frequency information to distinguish targets, achieving high classification accuracy.
FRONTIERS IN HUMAN NEUROSCIENCE
(2021)
Article
Neurosciences
Youhao Wang, Jingjing Luo, Yuzhu Guo, Qiang Du, Qiying Cheng, Hongbo Wang
Summary: The study demonstrated that for the neurofeedback group, ERP brain network parameters showed significant changes and trends, while for the non-feedback group, most network parameters did not change significantly. The short-term effects of MI-BCI training were not observed significantly in ERD analysis, but could be detected significantly by ERP-based network analysis.
FRONTIERS IN HUMAN NEUROSCIENCE
(2021)
Letter
Clinical Neurology
Belen Rubio Ballester, Nick S. Ward, Fran Brander, Martina Maier, Kate Kelly, Paul F. M. J. Verschure
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2022)
Review
Engineering, Biomedical
Jingjing Luo, Zhengrong Yan, Shijie Guo, Wei Chen
Summary: Atherosclerosis screening plays an important role in the transformation of the medical model from therapeutic medicine to preventive medicine. This study introduces five cutting-edge pervasive technologies for atherosclerosis screening, including iPPG, laser Doppler, RF, TI, optical fiber sensing, and piezoelectric sensor. These noninvasive and mobile technologies can detect physiological parameters related to atherosclerosis.
IEEE REVIEWS IN BIOMEDICAL ENGINEERING
(2022)
Article
Robotics
Fuhao Wang, Hongbo Wang, Jingjing Luo, Xiaoyang Kang, Haoyang Yu, Hao Lu, Yu Dong, Xiaoxu Jia
Summary: This letter presents a flexible tendon-driven continuum surgical manipulator called FLORA, which aims to solve the problems of low flexibility, poor internal extension, and chopstick effect in most laparoscopic surgical robots. The manipulator is composed of three independent flexible segments in series, driven by twelve tendons, and has good flexibility and rigidity. It also features a compact actuation unit and a kinematic modeling method based on piecewise constant curvature model, which can accurately model and fast decouple the manipulator.
IEEE ROBOTICS AND AUTOMATION LETTERS
(2022)
Article
Engineering, Electrical & Electronic
Qiliang Chen, Yulin Huang, Xing Zhu, Hong Lu, Zhongzhi Ji, Jiacheng Yang, Jingjing Luo
Summary: In this paper, a regression model using 3D convolution neural networks (CNN) for locating radial artery upon radius at the wrist using near-infrared picture sequences is proposed. Compared to previous 2D models, the 3D CNN model achieved superior performance accuracy and highlighted dynamic changes within image sequences.
EURASIP JOURNAL ON IMAGE AND VIDEO PROCESSING
(2022)
Article
Engineering, Electrical & Electronic
Yunjie Li, Min Wei, Qiliang Chen, Xing Zhu, Hui Li, Hongbo Wang, Jingjing Luo
Summary: Camera-based image sequences can be used to measure blood pressure continuously and noncontactly using a deep-learning approach called Hybrid D1DCnet. The model can predict systolic and diastolic blood pressure by analyzing forehead imaging photoplethysmography (iPPG) waveforms and personal information. The research demonstrates the feasibility and advantages of using this model to monitor circulatory health and contribute to the prevention and intervention of cardiovascular diseases.
IEEE SENSORS JOURNAL
(2023)
Article
Engineering, Electrical & Electronic
Jingjing Luo, Min Wei, Moyi Shi, Yunjie Li, Xing Zhu, Yang Zhou
Summary: This study proposes a novel cardiovascular health state detection procedure based on camera-based iPPG monitoring. The method achieves high accuracy in predicting whether subjects are CVDs relevant patients. The study emphasizes the advantages of using noncontact and high-dimensional features for cardiovascular health assessment.
IEEE SENSORS JOURNAL
(2023)
Review
Clinical Neurology
Martina Maier, Belen Rubio Ballester, Armin Duff, Esther Duarte Oller, Paul F. M. J. Verschure
NEUROREHABILITATION AND NEURAL REPAIR
(2019)