DecreasedNpas4andArcmRNA Levels in the Hippocampus of Aged Memory-Impaired Wild-Type But Not Memory Preserved 11β-HSD1 Deficient Mice

Intrahippocampal glucocorticoids generated by 11β-HSD1 affect memory in aged mice

(2015) Joyce L.W. Yau et al.   NEUROBIOLOGY OF AGING

Short-term inhibition of 11β-hydroxysteroid dehydrogenase type 1 reversibly improves spatial memory but persistently impairs contextual fear memory in aged mice

(2015) Nicola Wheelan et al.   NEUROPHARMACOLOGY

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

A fine balance: Regulation of hippocampal Arc/Arg3.1 transcription, translation and degradation in a rat model of normal cognitive aging

(2014) Bonnie R. Fletcher et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Towards a better understanding of cognitive behaviors regulated by gene expression downstream of activity-dependent transcription factors

(2014) Mio Nonaka et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Glucocorticoid-Dependent Hippocampal Transcriptome in Male Rats: Pathway-Specific Alterations With Aging

(2013) Kuey-Chu Chen et al.   ENDOCRINOLOGY

Sustained Transcription of the Immediate Early Gene Arc in the Dentate Gyrus after Spatial Exploration

(2013) V. Ramirez-Amaya et al.   JOURNAL OF NEUROSCIENCE

The activity-dependent transcription factor NPAS4 regulates domain-specific inhibition

(2013) Brenda L. Bloodgood et al.   NATURE

Reduced neuroplasticity in aged rats: a role for the neurotrophin brain-derived neurotrophic factor

(2013) Francesca Calabrese et al.   NEUROBIOLOGY OF AGING

Behaviorally Activated mRNA Expression Profiles Produce Signatures of Learning and Enhanced Inhibition in Aged Rats with Preserved Memory

(2013) Rebecca P. Haberman et al.   PLoS One

Activity-DependentNPAS4Expression and the Regulation of Gene Programs Underlying Plasticity in the Central Nervous System

(2013) José Fernando Maya-Vetencourt   NEURAL PLASTICITY

Transcriptional suppression of the neuronal PAS domain 4 (Npas4) gene by stress via the binding of agonist-bound glucocorticoid receptor to its promoter

(2012) Yoko Furukawa-Hibi et al.   JOURNAL OF NEUROCHEMISTRY

Memory aging and brain maintenance

(2012) Lars Nyberg et al.   TRENDS IN COGNITIVE SCIENCES

Local amplification of glucocorticoids in the aging brain and impaired spatial memory

(2012) Joyce L. W. Yau et al.   Frontiers in Aging Neuroscience

11 -Hydroxysteroid Dehydrogenase Type 1 Deficiency Prevents Memory Deficits with Aging by Switching from Glucocorticoid Receptor to Mineralocorticoid Receptor-Mediated Cognitive Control

(2011) J. L. W. Yau et al.   JOURNAL OF NEUROSCIENCE

The Neuronal PAS Domain Protein 4 (Npas4) Is Required for New and Reactivated Fear Memories

(2011) Jonathan E. Ploski et al.   PLoS One

Npas4 Regulates a Transcriptional Program in CA3 Required for Contextual Memory Formation

(2011) K. Ramamoorthi et al.   SCIENCE

11β-Hydroxysteroid dehydrogenases and the brain: From zero to hero, a decade of progress

(2010) Caitlin S. Wyrwoll et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Chronic restraint stress impairs neurogenesis and hippocampus-dependent fear memory in mice: possible involvement of a brain-specific transcription factor Npas4

(2010) Jaesuk Yun et al.   JOURNAL OF NEUROCHEMISTRY

11 -Hydroxysteroid Dehydrogenase Type 1 Expression Is Increased in the Aged Mouse Hippocampus and Parietal Cortex and Causes Memory Impairments

(2010) M. C. Holmes et al.   JOURNAL OF NEUROSCIENCE

Partial Deficiency or Short-Term Inhibition of 11 -Hydroxysteroid Dehydrogenase Type 1 Improves Cognitive Function in Aging Mice

(2010) K. Sooy et al.   JOURNAL OF NEUROSCIENCE

Age-related changes in Arc transcription and DNA methylation within the hippocampus

(2010) M.R. Penner et al.   NEUROBIOLOGY OF AGING

Hypothalamic-Pituitary-Adrenal Axis Abnormalities in Response to Deletion of 11β-HSD1 is Strain-Dependent

(2009) R. N. Carter et al.   JOURNAL OF NEUROENDOCRINOLOGY

Prominent hippocampal CA3 gene expression profile in neurocognitive aging

(2009) Rebecca P. Haberman et al.   NEUROBIOLOGY OF AGING

Memory-enhancing corticosterone treatment increases amygdala norepinephrine and Arc protein expression in hippocampal synaptic fractions

(2009) Jayme R. McReynolds et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

The Arc of synaptic memory

(2009) Clive R. Bramham et al.   EXPERIMENTAL BRAIN RESEARCH

A comparison of meta-analysis methods for detecting differentially expressed genes in microarray experiments

(2008) Fangxin Hong et al.   BIOINFORMATICS

Shared Gene Expression Alterations in Schizophrenia and Bipolar Disorder

(2008) Ling Shao et al.   BIOLOGICAL PSYCHIATRY

Hippocampal gene expression changes during age-related cognitive decline

(2008) Traci L. Pawlowski et al.   BRAIN RESEARCH

Immediate-Early Gene Expression at Rest Recapitulates Recent Experience

(2008) D. F. Marrone et al.   JOURNAL OF NEUROSCIENCE

Activity-dependent regulation of inhibitory synapse development by Npas4

(2008) Yingxi Lin et al.   NATURE

Genome-wide analysis of aging and learning-related genes in the hippocampal dentate gyrus

(2008) Corinna Burger et al.   NEUROBIOLOGY OF LEARNING AND MEMORY