In vivo and in vitro effects of multiple sclerosis immunomodulatory therapeutics on glutamatergic excitotoxicity

Excitatory amino acid transporters: recent insights into molecular mechanisms, novel modes of modulation and new therapeutic possibilities

(2015) Anders A Jensen et al.   CURRENT OPINION IN PHARMACOLOGY

DMF, but not other fumarates, inhibits NF-κB activity in vitro in an Nrf2-independent manner

(2015) Geoffrey O. Gillard et al.   JOURNAL OF NEUROIMMUNOLOGY

FRET based ratiometric Ca2+ imaging to investigate immune-mediated neuronal and axonal damage processes in experimental autoimmune encephalomyelitis

(2015) Volker Siffrin et al.   JOURNAL OF NEUROSCIENCE METHODS

Molecular mechanisms linking neuroinflammation and neurodegeneration in MS

(2014) Erik Ellwardt et al.   EXPERIMENTAL NEUROLOGY

Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis

(2014) Manuel A. Friese et al.   Nature Reviews Neurology

Spatiotemporal Imaging of Glutamate-Induced Biophotonic Activities and Transmission in Neural Circuits

(2014) Rendong Tang et al.   PLoS One

Effects of antagonists of glutamate receptors on pro-inflammatory cytokines in the brain cortex of rats subjected to experimental autoimmune encephalomyelitis

(2013) Grzegorz Sulkowski et al.   JOURNAL OF NEUROIMMUNOLOGY

Excitotoxicity and stroke: Identifying novel targets for neuroprotection

(2013) Ted Weita Lai et al.   PROGRESS IN NEUROBIOLOGY

Neurons as targets for T cells in the nervous system

(2013) Roland S. Liblau et al.   TRENDS IN NEUROSCIENCES

Correlating Calcium Binding, Förster Resonance Energy Transfer, and Conformational Change in the Biosensor TN-XXL

(2012) Anselm Geiger et al.   BIOPHYSICAL JOURNAL

Three-dimensional cell culture: the missing link in drug discovery

(2012) Susan Breslin et al.   DRUG DISCOVERY TODAY

Effects of dimethyl fumarate on neuroprotection and immunomodulation

(2012) Philipp Albrecht et al.   Journal of Neuroinflammation

Fingolimod protects cultured cortical neurons against excitotoxic death

(2012) Luisa Di Menna et al.   PHARMACOLOGICAL RESEARCH

Oral fingolimod rescues the functional deficits of synapses in experimental autoimmune encephalomyelitis

(2011) S Rossi et al.   BRITISH JOURNAL OF PHARMACOLOGY

A new vicious cycle involving glutamate excitotoxicity, oxidative stress and mitochondrial dynamics

(2011) D Nguyen et al.   Cell Death & Disease

Expanding Two-Photon Intravital Microscopy to the Infrared by Means of Optical Parametric Oscillator

(2010) Josephine Herz et al.   BIOPHYSICAL JOURNAL

In Vivo Imaging of Partially Reversible Th17 Cell-Induced Neuronal Dysfunction in the Course of Encephalomyelitis

(2010) Volker Siffrin et al.   IMMUNITY

Multiple sclerosis – candidate mechanisms underlying CNS atrophy

(2010) Volker Siffrin et al.   TRENDS IN NEUROSCIENCES

Glutamate receptors on myelinated spinal cord axons: I. GluR6 kainate receptors

(2009) Mohamed Ouardouz et al.   ANNALS OF NEUROLOGY

Glutamate receptors on myelinated spinal cord axons: II. AMPA and GluR5 receptors

(2009) Mohamed Ouardouz et al.   ANNALS OF NEUROLOGY

AIF: Not Just an Apoptosis-Inducing Factor

(2009) Nicholas Joza et al.   Annals of the New York Academy of Sciences

Differential immune cell dynamics in the CNS cause CD4+ T cell compartmentalization

(2009) Volker Siffrin et al.   BRAIN

Sphingosine-1-phosphate receptors mediate neuromodulatory functions in the CNS

(2009) Laura J. Sim-Selley et al.   JOURNAL OF NEUROCHEMISTRY

A genetically encoded calcium indicator for chronic in vivo two-photon imaging

(2008) Marco Mank et al.   NATURE METHODS

Glutamate Receptor Expression in Multiple Sclerosis Lesions

(2007) Jia Newcombe et al.   BRAIN PATHOLOGY