Fas apoptosis inhibitory molecules: more than death-receptor antagonists in the nervous system

The X-linked inhibitor of apoptosis regulates long-term depression and learning rate

(2016) Julien Gibon et al.   FASEB JOURNAL

Loss of Fas apoptosis inhibitory molecule leads to spontaneous obesity and hepatosteatosis

(2016) J Huo et al.   Cell Death & Disease

The Enemy within: Innate Surveillance-Mediated Cell Death, the Common Mechanism of Neurodegenerative Disease

(2016) Robert I. Richards et al.   Frontiers in Neuroscience

The transmembrane Bax inhibitor motif (TMBIM) containing protein family: Tissue expression, intracellular localization and effects on the ER CA2+-filling state

(2015) Dmitrij A. Lisak et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells

(2015) Jorge Urresti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The contribution of neuroinflammation to amyloid toxicity in Alzheimer's disease

(2015) Myles R. Minter et al.   JOURNAL OF NEUROCHEMISTRY

Immune attack: the role of inflammation in Alzheimer disease

(2015) Frank L. Heppner et al.   NATURE REVIEWS NEUROSCIENCE

High Throughput Sequencing Identifies MicroRNAs Mediating α-Synuclein Toxicity by Targeting Neuroactive-Ligand Receptor Interaction Pathway in Early Stage of Drosophila Parkinson's Disease Model

(2015) Yan Kong et al.   PLoS One

Amyloid-β reduces the expression of neuronal FAIM-L, thereby shifting the inflammatory response mediated by TNFα from neuronal protection to death

(2015) P Carriba et al.   Cell Death & Disease

The neurite growth inhibitory effects of soluble TNFα on developing sympathetic neurons are dependent on developmental age

(2015) Aoife M. Nolan et al.   DIFFERENTIATION

A Global Regulatory Mechanism for Activating an Exon Network Required for Neurogenesis

(2014) Bushra Raj et al.   MOLECULAR CELL

TNF-α/TNFR1 Signaling Is Required for the Development and Function of Primary Nociceptors

(2014) Michael A. Wheeler et al.   NEURON

TMBIM protein family: ancestral regulators of cell death

(2014) D Rojas-Rivera et al.   ONCOGENE

Toso controls encephalitogenic immune responses by dendritic cells and regulatory T cells

(2014) D. Brenner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for a pH-sensitive calcium leak across membranes

(2014) Y. Chang et al.   SCIENCE

MYCN repression of Lifeguard/FAIM2 enhances neuroblastoma aggressiveness

(2014) L Planells-Ferrer et al.   Cell Death & Disease

Structure determination of human Fas apoptosis inhibitory molecule and identification of the critical residues linking the interdomain interaction to the anti-apoptotic activity

(2014) Guoming Li et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Amyloid Beta, TNFα and FAIM-L; Approaching New Therapeutic Strategies for AD

(2014) Paulina Carriba et al.   Frontiers in Neurology

Modulation of Hippocampal Neuroplasticity by Fas/CD95 Regulatory Protein 2 (Faim2) in the Course of Bacterial Meningitis

(2013) Simone C. Tauber et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

FAIM-L Is an IAP-Binding Protein That Inhibits XIAP Ubiquitinylation and Protects from Fas-Induced Apoptosis

(2013) R. S. Moubarak et al.   JOURNAL OF NEUROSCIENCE

TNFα reverse signaling promotes sympathetic axon growth and target innervation

(2013) Lilian Kisiswa et al.   NATURE NEUROSCIENCE

Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death

(2013) Dimitry Ofengeim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Microglial derived tumor necrosis factor-α drives Alzheimer's disease-related neuronal cell cycle events

(2013) Kiran Bhaskar et al.   NEUROBIOLOGY OF DISEASE

Involvement of Toso in activation of monocytes, macrophages, and granulocytes

(2013) K. S. Lang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TNFα induces survival through the FLIP-L-dependent activation of the MAPK/ERK pathway

(2013) F Marques-Fernandez et al.   Cell Death & Disease

Distinct pathways mediate axon degeneration during apoptosis and axon-specific pruning

(2013) Corey L. Cusack et al.   Nature Communications

XIAP Regulates Caspase Activity in Degenerating Axons

(2013) Nicolas Unsain et al.   Cell Reports

Regulation of neurite growth by tumour necrosis superfamily member RANKL

(2013) H. Gutierrez et al.   Open Biology

Role of BI-1 (TEGT)-mediated ERK1/2 activation in mitochondria-mediated apoptosis and splenomegaly in BI-1 transgenic mice

(2012) Jung-Hyun Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Response: antiapoptotic function of Toso (Faim3) in death receptor signaling

(2012) X.-H. Nguyen et al.   BLOOD

Endoplasmic reticulum protein BI-1 regulates Ca2+-mediated bioenergetics to promote autophagy

(2012) R. Sano et al.   GENES & DEVELOPMENT

Axonal transport of neural membrane protein 35 mRNA increases axon growth

(2012) Tanuja T. Merianda et al.   JOURNAL OF CELL SCIENCE

Toso, a Functional IgM Receptor, Is Regulated by IL-2 in T and NK Cells

(2012) Y. Murakami et al.   JOURNAL OF IMMUNOLOGY

A Caspase Cascade Regulating Developmental Axon Degeneration

(2012) D. J. Simon et al.   JOURNAL OF NEUROSCIENCE

MiR-133b Targets Antiapoptotic Genes and Enhances Death Receptor-Induced Apoptosis

(2012) Juan P. Patron et al.   PLoS One

The intracellular portion of GITR enhances NGF-promoted neurite growth through an inverse modulation of Erk and NF-κB signalling

(2012) Laura McKelvey et al.   Biology Open

Toso regulates the balance between apoptotic and nonapoptotic death receptor signaling by facilitating RIP1 ubiquitination

(2011) X.-H. Nguyen et al.   BLOOD

Fas/CD95 Regulatory Protein Faim2 Is Neuroprotective after Transient Brain Ischemia

(2011) A. Reich et al.   JOURNAL OF NEUROSCIENCE

Antiapoptotic protein Lifeguard is required for survival and maintenance of Purkinje and granular cells

(2011) T. Hurtado de Mendoza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of neural process growth, elaboration and structural plasticity by NF-κB

(2011) Humberto Gutierrez et al.   TRENDS IN NEUROSCIENCES

Transactivation of lifeguard (LFG) by Akt-/LEF-1 pathway in MCF-7 and MDA-MB 231 human breast cancer cells

(2010) Vesna Bucan et al.   APOPTOSIS

Caspase-3 Activation via Mitochondria Is Required for Long-Term Depression and AMPA Receptor Internalization

(2010) Zheng Li et al.   CELL

Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization

(2010) L. F. Gumy et al.   RNA

Genetic deletion of faim reveals its role in modulating c-FLIP expression during CD95-mediated apoptosis of lymphocytes and hepatocytes

(2009) J Huo et al.   CELL DEATH AND DIFFERENTIATION

Life and death by death receptors

(2009) Maria Eugenia Guicciardi et al.   FASEB JOURNAL

Fas Apoptosis Inhibitory Molecule Contains a Novel β-Sandwich in Contact with a Partially Ordered Domain

(2009) Michael Hemond et al.   JOURNAL OF MOLECULAR BIOLOGY

Developmental Regulation of Sensory Neurite Growth by the Tumor Necrosis Factor Superfamily Member LIGHT

(2009) N. Gavalda et al.   JOURNAL OF NEUROSCIENCE

Overexpression of the Fas-inhibitory molecule TOSO–a novel antiapoptotic factor in chronic lymphocytic leukemia

(2009) Christian Philipp Pallasch et al.   LEUKEMIA & LYMPHOMA

A global view of protein expression in human cells, tissues, and organs

(2009) Fredrik Pontén et al.   Molecular Systems Biology

XIAP discriminates between type I and type II FAS-induced apoptosis

(2009) Philipp J. Jost et al.   NATURE

SAGE analysis demonstrates increased expression of TOSO contributing to Fas-mediated resistance in CLL

(2008) R. Proto-Siqueira et al.   BLOOD

Overexpression of TOSO in CLL is triggered by B-cell receptor signaling and associated with progressive disease

(2008) C. P. Pallasch et al.   BLOOD

Death Receptors and Caspases But Not Mitochondria Are Activated in the GDNF- or BDNF-Deprived Dopaminergic Neurons

(2008) L.-y. Yu et al.   JOURNAL OF NEUROSCIENCE

IAPs: What's in a Name?

(2008) Srinivasa M. Srinivasula et al.   MOLECULAR CELL

Regulation of axonal and dendritic growth by the extracellular calcium-sensing receptor

(2008) Thomas N Vizard et al.   NATURE NEUROSCIENCE

A Model for Neuronal Competition During Development

(2008) C. D. Deppmann et al.   SCIENCE