Cell death caused by the synergistic effects of zinc and dopamine is mediated by a stress sensor gene Gadd45b - implication in the pathogenesis of Parkinson's disease

Gadd45b prevents autophagy and apoptosis against rat cerebral neuron oxygen-glucose deprivation/reperfusion injury

(2016) Guoqian He et al.   APOPTOSIS

Zinc preconditioning protects against neuronal apoptosis through the mitogen-activated protein kinase-mediated induction of heat shock protein 70

(2015) Jeong-Min Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oxidative stress and Parkinson’s disease

(2015) Javier Blesa et al.   Frontiers in Neuroanatomy

Sex differences in Parkinson’s disease

(2014) Glenda E. Gillies et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Induction of GADD45α protects M17 neuroblastoma cells against MPP*

(2014) Xiao-Feng Wang et al.   IUBMB LIFE

The JNK inhibitor, SP600125, potentiates the glial response and cell death induced by methamphetamine in the mouse striatum

(2013) Andres Urrutia et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Role of Oxidative Stress in Parkinson's Disease

(2013) Onyou Hwang   Experimental Neurobiology

Zinc chloride exposure increases heme oxygenase-1 expression in MDPC-23 odontoblast-like cells

(2012) Hiroyo Karube et al.   ARCHIVES OF ORAL BIOLOGY

Gadd45a and Gadd45b modulate innate immune functions of granulocytes and macrophages by differential regulation of p38 and JNK signaling

(2012) Dominic M. Salerno et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mitochondrial Inhibitor Models of Huntington’s Disease and Parkinson’s Disease Induce Zinc Accumulation and Are Attenuated by Inhibition of Zinc Neurotoxicity in vitro or in vivo

(2012) Christian T. Sheline et al.   Neurodegenerative Diseases

Zinc homeostasis and signaling in health and diseases

(2011) Toshiyuki Fukada et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Induction of DNA Damage-Inducible Gene GADD45  Contributes to Sorafenib-Induced Apoptosis in Hepatocellular Carcinoma Cells

(2010) D.-L. Ou et al.   CANCER RESEARCH

Gadd45  is a novel mediator of cardiomyocyte apoptosis induced by ischaemia/hypoxia

(2010) M.-Y. Kim et al.   CARDIOVASCULAR RESEARCH

Cytosolic zinc buffering and muffling: Their role in intracellular zinc homeostasis

(2010) Robert A. Colvin et al.   Metallomics

Parkinson’s disease: oxidative stress and therapeutic approaches

(2010) Sankar Surendran et al.   NEUROLOGICAL SCIENCES

Cytosolic labile zinc accumulation in degenerating dopaminergic neurons of mouse brain after MPTP treatment

(2009) Joo-Yong Lee et al.   BRAIN RESEARCH

Gadd45 Proteins as Critical Signal Transducers Linking NF-κB to MAPK Cascades

(2009) Z. Yang et al.   CURRENT CANCER DRUG TARGETS

Environmental-induced oxidative stress in neurodegenerative disorders and aging

(2008) Lucia Migliore et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Metallothionein redox biology in the cytoprotective and cytotoxic functions of zinc

(2007) Wolfgang Maret   EXPERIMENTAL GERONTOLOGY