Reduced glutathione biosynthesis inDrosophila melanogastercauses neuronal defects linked to copper deficiency

X-linked spinal muscular atrophy in mice caused by autonomous loss of ATP7A in the motor neuron

(2015) Victoria L Hodgkinson et al.   JOURNAL OF PATHOLOGY

Copper at synapse: Release, binding and modulation of neurotransmission

(2015) Nadia D'Ambrosi et al.   NEUROCHEMISTRY INTERNATIONAL

Copper overload and deficiency both adversely affect the central nervous system of Drosophila

(2014) Joab E. C. Hwang et al.   Metallomics

Redox sulfur chemistry of the copper chaperone Atox1 is regulated by the enzyme glutaredoxin 1, the reduction potential of the glutathione couple GSSG/2GSH and the availability of Cu(i)

(2014) Jens Brose et al.   Metallomics

FlyBase: introduction of the Drosophila melanogaster Release 6 reference genome assembly and large-scale migration of genome annotations

(2014) G. dos Santos et al.   NUCLEIC ACIDS RESEARCH

Cellular glutathione plays a key role in copper uptake mediated by human copper transporter 1

(2013) Edward B. Maryon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Involvement of Redox State in the Aging of Drosophila melanogaster

(2013) William C. Orr et al.   ANTIOXIDANTS & REDOX SIGNALING

Brain metal accumulation in Wilson's disease

(2013) T. Litwin et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Diminishing glutathione availability and age-associated decline in neuronal excitability

(2013) Shawn N. Watson et al.   NEUROBIOLOGY OF AGING

Glutaredoxins in Thiol/Disulfide Exchange

(2012) Christopher Horst Lillig et al.   ANTIOXIDANTS & REDOX SIGNALING

Inherited Copper Transport Disorders: Biochemical Mechanisms, Diagnosis, and Treatment

(2012) Hiroko Kodama et al.   CURRENT DRUG METABOLISM

Functional Partnership of the Copper Export Machinery and Glutathione Balance in Human Cells

(2012) Yuta Hatori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

γ-Glutamylcysteine detoxifies reactive oxygen species by acting as glutathione peroxidase-1 cofactor

(2012) Ruben Quintana-Cabrera et al.   Nature Communications

Posttranslational Modification of Cysteine in Redox Signaling and Oxidative Stress: Focus on S-Glutathionylation

(2011) John J. Mieyal et al.   ANTIOXIDANTS & REDOX SIGNALING

Unification of the Copper(I) Binding Affinities of the Metallo-chaperones Atx1, Atox1, and Related Proteins

(2011) Zhiguang Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATP7A-related copper transport diseases—emerging concepts and future trends

(2011) Stephen G. Kaler   Nature Reviews Neurology

Detection of Genetically Altered Copper Levels in Drosophila Tissues by Synchrotron X-Ray Fluorescence Microscopy

(2011) Jessica C. Lye et al.   PLoS One

Role of Glutaredoxin1 and Glutathione in Regulating the Activity of the Copper-transporting P-type ATPases, ATP7A and ATP7B

(2010) William C. J. Singleton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tissue-specific interplay between copper uptake and efflux in Drosophila

(2010) Tim Binks et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Affinity gradients drive copper to cellular destinations

(2010) Lucia Banci et al.   NATURE

Menkes disease

(2009) Zeynep Tümer et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Bursicon Functions within the Drosophila CNS to Modulate Wing Expansion Behavior, Hormone Secretion, and Cell Death

(2009) N. C. Peabody et al.   JOURNAL OF NEUROSCIENCE