Article
Medicine, General & Internal
Meghann Pasternak, Ping Liu, Robert Quinn, Meghan Elliott, Tyrone Gorden Harrison, Brenda Hemmelgarn, Ngan Lam, Paul Ronksley, Marcello Tonelli, Pietro Ravani
Summary: This study aims to assess the 5-year probability of CKD regression in patients with newly diagnosed CKD, taking into account the competing risks of CKD progression and death, and investigate the association between albuminuria level and CKD regression.
Editorial Material
Urology & Nephrology
Sho Hasegawa, Masaomi Nangaku
Summary: This study suggests that SGLT2 inhibitors, such as dapagliflozin, may reduce the risk of abrupt declines in kidney function in patients with chronic kidney disease.
KIDNEY INTERNATIONAL
(2022)
Article
Medical Laboratory Technology
Sushma Thimmaiah Kanakalakshmi, Shilna Muttickal Swaminathan, Pooja Basthi Mohan, Shankar Prasad Nagaraju, Mohan Bhojaraja, Sindhura Lakshmi Koulmane Laxminarayana
Summary: Diabetic kidney disease (DKD) is a common cause of renal failure in chronic kidney disease (CKD) patients. The limitations of current diagnostic markers call for the search of novel biomarkers. Microparticles, which play a role in cell-to-cell communication, show potential in early diagnosis and prognosis of DKD.
CLINICA CHIMICA ACTA
(2022)
Article
Urology & Nephrology
Qi Li, Hiroshi Nishi, Reiko Inoue, Sae Ueda, Masaomi Nangaku
Summary: A study in Japan found a correlation between the prevalence and awareness of chronic kidney disease among the elderly population. By analyzing nationwide health checkup data, researchers discovered that the rate of kidney dysfunction was positively correlated with the percentage of individuals aware of their condition.
Article
Multidisciplinary Sciences
Temesgen Fiseha, Ermiyas Ahmed, Semagn Chalie, Angesom Gebreweld
Summary: A study in Northeast Ethiopia found a high prevalence of impaired renal function and albuminuria among adult patients admitted to the internal medicine wards. However, awareness of the condition was low among patients. Older age, family history of kidney disease, diabetes, hypertension, and HIV were identified as factors associated with impaired renal function and albuminuria. Early detection and intervention strategies are needed to address this issue in inpatient settings.
Article
Medicine, General & Internal
Hui-Ju Tsai, Chih-Hsing Hung, Chih-Wen Wang, Hung-Pin Tu, Chiu-Hui Li, Chun-Chi Tsai, Wen-Yi Lin, Szu-Chia Chen, Chao-Hung Kuo
Summary: This study found significant associations between high blood lead and high urine nickel, manganese, copper, and cadmium with proteinuria in the general population in Southern Taiwan. Additionally, interactions between blood lead and urine chromium, and between urine cadmium and copper, had significant effects on proteinuria.
Article
Pediatrics
Katarzyna Mackowiak-Lewandowicz, Danuta Ostalska-Nowicka, Katarzyna Zaorska, Elzbieta Kaczmarek, Jacek Zachwieja, Martin Witt, Michal Nowicki
Summary: By studying the expression pattern of lipid metabolism and kidney damage markers in obese adolescents, it is possible to predict the risk of developing CKD. Increased serum concentrations of cholesterol, triglycerides, and urine concentration of neutrophil gelatinase-associated lipocalin may serve as potential predictors for CKD development in obese adolescents.
PEDIATRIC NEPHROLOGY
(2022)
Letter
Medicine, General & Internal
Jennifer Bragg-Gresham, Xiaosong Zhang, Dao Le, Michael Heung, Vahakn Shahinian, Hal Morgenstern, Rajiv Saran
Summary: This cross-sectional study investigates the impact of removing the Black race coefficient from a GFR estimating equation on the estimated prevalence of chronic kidney disease in the general Black population and among Black veterans in the US.
Article
Nutrition & Dietetics
Anthony Kityo, Sang-Ah Lee
Summary: This cross-sectional study investigated the association between the consumption of ultra-processed food (UPF) and chronic kidney disease (CKD) in Korea. The results showed that a higher proportion of UPF intake was associated with an increased prevalence of CKD and a decreased glomerular filtration rate (eGFR).
Article
Medicine, General & Internal
Rihwa Choi, Sang Gon Lee, Eun Hee Lee
Summary: This retrospective study reviewed the estimated glomerular filtration rates (eGFR) calculated by three equations and investigated the changes in prevalence of chronic kidney diseases. The study found that the prevalence of decreased eGFR increased with age and that the equation based on CKD-EPI 2021 had a lower prevalence compared to the other equations.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Jinsung Park, Dong Wook Shin, Kyungdo Han, Dahye Kim, Sohyun Chun, Hye Ryoun Jang
Summary: The study found that milder stages of chronic kidney disease are associated with an increased risk of kidney cancer. Additionally, lower estimated glomerular filtration rate and severity of proteinuria are positively correlated with the risk of kidney cancer, with a possible synergistic effect between the two factors leading to an increased incidence of kidney cancer.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Urology & Nephrology
Carla Santos-Araujo, Luis Mendonca, Daniel Seabra Carvalho, Filipa Bernardo, Marisa Pardal, Joao Couceiro, Hugo Martinho, Cristina Gavina, Tiago Taveira-Gomes, Ricardo Jorge Dinis-Oliveira
Summary: This study provides the first real-world based estimation of the prevalence of chronic kidney disease (CKD) in a large, unselected Portuguese population. The overall estimated prevalence of CKD was 9.8% and was higher in females than males. This study may help healthcare providers in formulating policies and strategies focused on preventing CKD and improving cardiovascular outcomes.
CLINICAL KIDNEY JOURNAL
(2023)
Article
Nutrition & Dietetics
Young Su Joo, Hyung Woo Kim, Sangmi Lee, Ki Heon Nam, Hae-Ryong Yun, Jong Hyun Jhee, Seung Hyeok Han, Tae-Hyun Yoo, Shin-Wook Kang, Jung Tak Park
Summary: This study used data from the Korean Genome and Epidemiology Study to show that low dietary zinc intake may increase the risk of chronic kidney disease in individuals with normal renal function.
CLINICAL NUTRITION
(2021)
Article
Medicine, General & Internal
Ping Liu, Rob R. Quinn, Ngan N. Lam, Huda Al-Wahsh, Manish M. Sood, Navdeep Tangri, Marcello Tonelli, Pietro Ravani
Summary: This study found that with advancing age, CKD regression and death were more likely than CKD progression or kidney failure. These findings have important implications for patient care and for assessing the potential effect of population aging on the burden of CKD.
Review
Food Science & Technology
Lajos Zsom, Marianna Zsom, Sohail Abdul Salim, Tibor Fulop
Summary: Estimated GFR (eGFR) is widely used to predict the progression of chronic kidney disease (CKD) and the need for dialysis, but it has several limitations, including only reflecting one physiological function of the kidney, depending on non-renal factors, being influenced by dietary intake and cardiovascular status, and not correlating with GFR in certain conditions. Many clinicians rely too heavily on eGFR as a valid reflection of renal function and a reliable diagnostic tool for CKD.
Article
Gastroenterology & Hepatology
Jae-woo Lee, Eun-A Choi, Ye-Seul Kim, Yonghwan Kim, Hyo-Sun You, Ye-Eun Han, Hyeong-Seop Kim, Yoon-Jong Bae, Joungyoun Kim, Hee-Taik Kang
Summary: This study found that individuals with diabetes who use metformin have a significantly lower risk of developing colorectal cancer compared to those who do not use metformin.
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
(2021)
Article
Nutrition & Dietetics
Woojung Yang, Jong Hun Lee, Jae-woo Lee, Yonghwan Kim, Ye-Seul Kim, Hyo-Sun You, Hee-Taik Kang
Summary: The study found an association between omega 3FA ratio and subclinical inflammation in men, with a decrease in prevalence of subclinical inflammation in males as the omega 3FA ratio increased. However, there was no significant difference in prevalence among quartile groups in females.
Article
Multidisciplinary Sciences
Joungyoun Kim, Hyeong-Seop Kim, Yun-Jong Bae, Hyeong-Chul Lee, Jae-woo Lee, Hee-Taik Kang
Summary: This study found no significant differences in efficacy between statins in preventing recurrence of CCVD events and/or death in CCVD patients.
Article
Environmental Sciences
Yonghwan Kim, Hee-Taik Kang, Duk-Chul Lee
Summary: Melatonin supplementation improved sleep quality but did not show significant effects on cardiometabolic parameters like arterial stiffness, mtDNA, or insulin resistance. Further research, including longer-term studies with higher doses of melatonin, is needed to confirm these findings.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Medicine, General & Internal
Joungyoun Kim, Yoon-Jong Bae, Jae-woo Lee, Ye-seul Kim, Yonghwan Kim, Hyo-Sun You, Hyeong-Seop Kim, Eun-A Choi, Ye-Eun Han, Hee-Taik Kang
Summary: The study showed that metformin use in diabetic cancer survivors reduced all-cause mortality rates. Particularly, metformin use after cancer diagnosis, rather than before, was inversely associated with overall mortality. Active treatment with metformin for diabetic cancer survivors after cancer diagnosis can improve their survival rates.
Article
Health Care Sciences & Services
Moon Kyung Joo, Ji Won Yoo, Zahra Mojtahedi, Pearl Kim, Jinwook Hwang, Ja Seol Koo, Hee-Taik Kang, Jay J. Shen
Summary: This study analyzed the hospitalization and palliative care consultation trends of gastric cancer patients in the US from 2009 to 2018. It found a decrease in hospitalizations, but an increase in the utilization of palliative care and procedures. The study suggests that palliative care consultation can help reduce medical resource utilization and hospital costs for patients with gastric cancer.
BMC HEALTH SERVICES RESEARCH
(2022)
Article
Medicine, General & Internal
Hyun Jeong Lee, Young Ae Kim, Seong Yeob Ryu, Mison Chun, Chang-Yeol Yim, Hee-Taik Kang, Jung Hun Kang, Jung-Sik Huh, Jong-Heun Kim, Kyu-Hyoung Lim, So-Youn Jung, Hyoung-Cheol Kwon, Eurah Goh, Yeon-Seung Lee, Hee Young Ju, E. Hwa Yun, Yoon Jung Chang
Summary: This study investigates the effects of the services provided by the Korean Cancer Survivorship Center Pilot Project on distress among cancer survivors. The results indicate that psychosocial and medical support can reduce the distress and physical and mental symptoms of cancer survivors.
FRONTIERS IN MEDICINE
(2022)
Article
Endocrinology & Metabolism
Yoon-Jong Bae, Sang-Jun Shin, Hee-Taik Kang
Summary: This study based on the Korean National Health Insurance Service-Health Screening cohort found an association between body mass index (BMI) and diabetes mellitus, cardio-cerebrovascular diseases, and mortality rate, showing a J-shaped relationship. Lower BMI and obesity were both associated with higher risks.
BMC ENDOCRINE DISORDERS
(2022)
Article
Public, Environmental & Occupational Health
Joungyoun Kim, Sang-Jun Shin, Jihyun Yoon, Hyeong-Seop Kim, Jae-Woo Lee, Ye-Seul Kim, Yongwhan Kim, Hyo-Sun You, Hee-Taik Kang
Summary: The consumption of opioids in Korea significantly increased over the 14-year study period, with a rising trend in the number of prescriptions and morphine milligram equivalent (MME) among registered individuals. The highest change was observed in the elderly population (60-69 years) and patients treated at general hospitals, and fentanyl prescriptions showed the most rapid increase.
EPIDEMIOLOGY AND HEALTH
(2022)
Review
Primary Health Care
Hee-Taik Kang
Summary: Health check-ups are an effective way to prevent diseases and maintain health by screening for risk factors and diagnosing diseases early. The National Health Screening Programs (NHSPs) in Korea contribute to improved cancer survival rates and control of chronic diseases. However, there is a need for improvement in various aspects of these programs.
KOREAN JOURNAL OF FAMILY MEDICINE
(2022)
Article
Primary Health Care
Joungyoun Kim, Yoon-Jong Bae, Hee-Taik Kang
Summary: This study investigated the association between metformin use and pancreatic cancer risk, finding that female diabetic patients using metformin are more likely to develop pancreatic cancer, while male diabetic patients using metformin have a similar risk to those not using it.
KOREAN JOURNAL OF FAMILY MEDICINE
(2022)
Article
Hematology
Hyo-Sun You, Sang-Jun Shin, Joungyoun Kim, Hee-Taik Kang
Summary: This study investigated the potential association between polycythemia and ischemic stroke. The results showed that participants with polycythemia had a higher risk of ischemic stroke compared to those with normal red blood cell levels.
EXPERT REVIEW OF HEMATOLOGY
(2023)
Article
Pharmacology & Pharmacy
Yonghwan Kim, Sang-Jun Shin, Jae-woo Lee, Ye-Seul Kim, Hyo-Sun You, Joungyoun Kim, Hee-Taik Kang
Summary: This study aimed to investigate the association between migraine and ischemic cardio-cerebrovascular disease (CCVD). The results showed that migraine increased the risk of CCVDs, and migraineurs treated with triptans and ergotamine had a lower risk compared to those who did not take these medications, especially in women.
CLINICAL DRUG INVESTIGATION
(2023)
Review
Peripheral Vascular Disease
Sungha Park, Jinho Shin, Sang Hyun Ihm, Kwang-il Kim, Hack-Lyoung Kim, Hyeon Chang Kim, Eun Mi Lee, Jang Hoon Lee, Shin Young Ahn, Eun Joo Cho, Ju Han Kim, Hee-Taik Kang, Hae-Young Lee, Sunki Lee, Woohyeun Kim, Jong-Moo Park
Summary: The prevalence of resistant hypertension is expected to rise due to the increasing prevalence of obesity, chronic kidney disease, and diabetes, all of which are associated with resistant hypertension. Common issues in patients with apparent treatment-resistant hypertension include pseudoresistant hypertension and non-adherence. Screening for secondary causes and emphasizing drug adherence through methods such as home blood pressure monitoring are important in managing resistant hypertension.
CLINICAL HYPERTENSION
(2023)
Article
Urology & Nephrology
Hyo-Sun You, Sang-Jun Shin, Joungyoun Kim, Hee-Taik Kang
Summary: Dyslipidemia is a known risk factor for chronic kidney disease (CKD). However, the use of statins in patients with hypercholesterolemia and normal renal function does not show a clear relationship with the incidence of CKD.
AMERICAN JOURNAL OF NEPHROLOGY
(2022)